Treatment of absolute painful glaucoma with dynamic arcs using novalis shaped beam radiosurgery

Journal Article · Wed Nov 15 04:00:00 EST 2006 · International Journal of Radiation Oncology, Biology and Physics

DOI:https://doi.org/10.1016/j.ijrobp.2006.04.060· OSTI ID:20850194

Gonzalez-Olhovich, Irene ^[1]; Celis, Miguel Angel ^[2]; Larraga-Gutierrez, Jose ^[2]; Lopez-Ayala, Temuchino ^[3]; Suarez-Campos, Jose ^[2]; Garcia-Garduno, Amanda ^[2]; Herrera-Gomez, Leopoldo ^[2]; Hernandez-Bojorquez, Mariana B.Sc. ^[2]

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1. Departamento de Neurooftalmologia, Instituto Nacional de Neurologia y Neurocirugia, Mexico DF (Mexico)
2. Unidad de Radioneurocirugia, Instituto Nacional de Neurologia y Neurocirugia, Mexico DF (Mexico)
3. Departamento de Neurocirugia, Instituto Nacional de Neurologia y Neurocirugia, Mexico DF (Mexico)

Purpose: We assessed the effect of shaped beam conformal stereotactic radiosurgery (SRS) in 1 patient with chronic painful glaucoma in one eye refractory to medical treatment. Methods and Materials: Left eye ciliary body was targeted at 18 Gy (90% isodose curve) with a dedicated linear accelerator (Novalis, BrainLAB, Germany) SRS. Interval follow-up was performed weekly for the first month, and every 2 months until 1 year was completed with clinical examinations and intraocular pressure (IOP) measurements. Results: Ocular pain resolved at 6 weeks after SRS treatment. IOP decreased and normalized at 1 year. Conclusions: We present a case in which SRS appears to be an effective treatment of chronic refractory painful glaucoma. Further Phase I studies are needed to know the best parameters for radiation dose, tolerance of organs at risk, and pathophysiologic effects.

• OSTI ID: 20850194
• Journal Information: International Journal of Radiation Oncology, Biology and Physics, Journal Name: International Journal of Radiation Oncology, Biology and Physics Journal Issue: 4 Vol. 66; ISSN IOBPD3; ISSN 0360-3016
• Country of Publication: United States
• Language: English

Related Subjects

62 RADIOLOGY AND NUCLEAR MEDICINE
BEAMS
HEALTH HAZARDS
ISODOSE CURVES
LINEAR ACCELERATORS
ORGANS
PAIN
PATIENTS
RADIATION DOSES
RADIOTHERAPY
REFRACTORIES
SURGERY
TOLERANCE