Comparison between Theoretical Calculation and Experimental Results of Excitation Functions for Production of Relevant Biomedical Radionuclides

Journal Article · Tue May 24 00:00:00 EDT 2005 · AIP Conference Proceedings

DOI:https://doi.org/10.1063/1.1945321· OSTI ID:20722505

Menapace, E ^[1]; Birattari, C; Bonardi, M L; Groppi, F; Morzenti, S; Zona, C ^[2]

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1. ENEA, Division for Advanced Physics Technologies, via Don Fiammelli 2, I-40128 Bologna (Italy)
2. Universita degli Studi di Milano, via F.lli Cervi 201, I-20090 Segrate, Milan (Italy)

The radionuclide production for biomedical applications has been brought up in the years, as a special nuclear application, at INFN LASA Laboratory, particularly in co-operation with the JRC-Ispra of EC. Mainly scientific aspects concerning radiation detection and the relevant instruments, the measurements of excitation functions of the involved nuclear reactions, the requested radiochemistry studies and further applications have been investigated. On the side of the nuclear data evaluations, based on nuclear model calculations and critically selected experimental data, the appropriate competence has been developed at ENEA Division for Advanced Physics Technologies. A series of high specific activity accelerator-produced radionuclides in no-carrier-added (NCA) form, for uses in metabolic radiotherapy and for PET radiodiagnostics, are investigated. In this work, last revised measurements and model calculations are reviewed for excitation functions of natZn(d,X)64Cu, 66Ga reactions, referring to irradiation experiments at K=38 variable energy Cyclotron of JRC-Ispra. Concerning the reaction data for producing 186gRe and 211At/211gPo (including significant emission spectra) and 210At, most recent and critically selected experimental results are considered and discussed in comparison with model calculations paying special care to pre-equilibrium effects estimate and to the appropriate overall parameterization. Model calculations are presented for 226Ra(p,2n)225Ac reaction, according to the working program of the ongoing IAEA CRP on the matter.

• OSTI ID: 20722505
• Journal Information: AIP Conference Proceedings, Vol. 769, Issue 1; Conference: International conference on nuclear data for science and technology, Santa Fe, NM (United States), 26 Sep - 1 Oct 2004; Other Information: DOI: 10.1063/1.1945321; (c) 2005 American Institute of Physics; Country of input: International Atomic Energy Agency (IAEA); ISSN 0094-243X
• Country of Publication: United States
• Language: English

Related Subjects

73 NUCLEAR PHYSICS AND RADIATION PHYSICS
ACTINIUM 225
ASTATINE 210
ASTATINE 211
COMPARATIVE EVALUATIONS
COPPER 64
DEUTERON REACTIONS
EMISSION SPECTRA
EXCITATION FUNCTIONS
GALLIUM 66
NUCLEAR MODELS
POTASSIUM 38
PROTON REACTIONS
PROTON-NUCLEON INTERACTIONS
RADIATION DETECTION
RADIOCHEMISTRY
RADIOTHERAPY
RADIUM 226
VARIABLE ENERGY CYCLOTRONS