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Modeling single molecule detection probabilities in microdroplets. Final report

Technical Report ·
DOI:https://doi.org/10.2172/206995· OSTI ID:206995

Numerical tools for modeling the fluorescence collected from a single molecule within a microsphere as a function of it`s position and orientation, the size of the droplet, the numerical aperture of the lens, the detection geometry, type of illumination, and the linewidth of the emitting molecule, are described.

Research Organization:
Army Research Lab., White Sands Missile Range, NM (United States)
Sponsoring Organization:
USDOE, Washington, DC (United States)
DOE Contract Number:
AI05-95OR22401
OSTI ID:
206995
Report Number(s):
DOE/OR/22401--T1; ON: DE96008232
Country of Publication:
United States
Language:
English

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