An evaluation of forward and inverse radiotherapy planning using Uelax-TMS (version 6.0) for lung cancer patients treated with rtog 93-11 dose-escalation protocol

Journal Article · Tue Sep 30 04:00:00 EDT 2003 · Medical Dosimetry

DOI:https://doi.org/10.1016/S0958-3947(03)00067-0· OSTI ID:20655452

Underwood, Lori J; Murray, Brad R; Robinson, Donald M; Field, G Colin; Roa, Wilson H

This study investigated the dosimetric advantages of inversely planned intensity-modulated radiotherapy (IMRT) over forward-planned conventional 3D conformal radiotherapy (3D-CRT) in treating lung cancer patients at escalated dose. Three consecutively accrued patients on the RTOG 93-11 dose-escalation protocol were replanned using IMRT with the same dosimetric rules, so that the isodose distributions and dose-volume histograms could be generated and compared. The Helax-TMS treatment planning system, with an IMRT optimization module (version 6.0), was used. In all cases, a consistent approach of inverse planning and set of dose-volume constraints (DVCs) provided improved critical structure sparing. However, the minimum dose in PTV was generally below that achieved with the corresponding forward planned 3D-CRT.

• OSTI ID: 20655452
• Journal Information: Medical Dosimetry, Journal Name: Medical Dosimetry Journal Issue: 3 Vol. 28; ISSN 0958-3947; ISSN MEDOEJ
• Country of Publication: United States
• Language: English

Related Subjects

62 RADIOLOGY AND NUCLEAR MEDICINE
CARCINOMAS
DOSIMETRY
EVALUATION
LUNGS
OPTIMIZATION
PATIENTS
PLANNING
RADIATION DOSE DISTRIBUTIONS
RADIATION DOSES
RADIOTHERAPY