Clinical outcomes of patients treated with the cutting balloon and Sr-90 {beta}-irradiation for instent restenosis
Journal Article
·
· Cardiovascular Radiation Medicine
Background: The cutting balloon (CB) is an emerging therapy for the treatment of instent restenosis (ISR), but its impact on the clinical outcomes of patients treated with intracoronary radiation therapy (IRT) with Sr-90 compared with conventional PTCA and IRT is not clearly defined. Methods: We compared the baseline demographics, angiographic characteristics and clinical outcomes of 102 consecutive patients with ISR treated either with CB+IRT (n=45) or with conventional PTCA+IRT (n=57). The combined endpoint was the occurrence of major adverse cardiac events (MACE), which was defined as a composite of death, myocardial infarction (MI) or target vessel revascularization (TVR) at 6 months. Results: The CB+IRT group had a shorter mean lesion length (14.3{+-}6.5 vs. 21.1{+-}15.7, P=.009), and greater utilization of glycoprotein IIb/IIIa inhibitors during the procedure (48.9% vs. 26.3%, P=.02) compared to the PTCA+IRT group. There were no significant differences in the baseline demographics, angiographic and procedural results, or subsequent MACE at 6 months between the two groups. Conclusion: The strategy of CB+IRT using Sr-90 for ISR is associated with similar procedural and clinical outcomes compared to conventional PTCA+IRT. Further study is warranted to determine which patient subgroups would derive the most benefit from this approach.
- OSTI ID:
- 20650535
- Journal Information:
- Cardiovascular Radiation Medicine, Journal Name: Cardiovascular Radiation Medicine Journal Issue: 1 Vol. 3; ISSN 1522-1865
- Country of Publication:
- United States
- Language:
- English
Similar Records
Predictors of late cardiac events following treatment with Sr-90 {beta}-irradiation for instent restenosis
Beta-radiation therapy for long lesions in native coronary vessels A matched comparison between de novo and in-stent restenotic lesions
Usefulness of tomographic thallium-201 imaging for detection of restenosis after percutaneous transluminal coronary angioplasty
Journal Article
·
Fri Feb 28 23:00:00 EST 2003
· Cardiovascular Radiation Medicine
·
OSTI ID:20650552
Beta-radiation therapy for long lesions in native coronary vessels A matched comparison between de novo and in-stent restenotic lesions
Journal Article
·
Fri Feb 28 23:00:00 EST 2003
· Cardiovascular Radiation Medicine
·
OSTI ID:20650554
Usefulness of tomographic thallium-201 imaging for detection of restenosis after percutaneous transluminal coronary angioplasty
Journal Article
·
Fri Nov 30 23:00:00 EST 1990
· American Journal of Cardiology; (USA)
·
OSTI ID:6273417