Liquid–Liquid Microfluidic Flows for Ultrafast 5-Hydroxymethyl Furfural Extraction

Chen, Tai-Ying; Desir, Pierre; Bracconi, Mauro; Saha, Basudeb; Maestri, Matteo; Vlachos, Dionisios G.

doi:10.1021/acs.iecr.0c05759

Liquid–Liquid Microfluidic Flows for Ultrafast 5-Hydroxymethyl Furfural Extraction

Journal Article · Tue Feb 23 00:00:00 EST 2021 · Industrial and Engineering Chemistry Research

DOI:https://doi.org/10.1021/acs.iecr.0c05759· OSTI ID:2007312

Chen, Tai-Ying ^[1]; Desir, Pierre ^[2]; ^[3]; Saha, Basudeb ^[4]; ^[3]; ^[5]

University of Delaware, Newark, DE (United States); University of Delaware
University of Delaware, Newark, DE (United States)
Politecnico di Milano (Italy)
Delaware Energy Institute (DEI), Newark, DE (United States)
University of Delaware, Newark, DE (United States); Delaware Energy Institute (DEI), Newark, DE (United States)

We study the effects of liquid–liquid flow patterns on the extraction of 5-hydroxymethyl furfural from the aqueous phase into an organic phase (methyl isobutyl ketone, ethyl acetate, and 2-pentanol) at ultrashort residence times of 0.2–20 s in a coiled capillary microchannel. Slug, droplet, slug-droplet, dispersed, parallel, annular, and irregular two-phase flow patterns are generated. We evaluate the extraction efficiency and the volumetric mass transfer coefficient via experiments and computational fluid dynamics (CFD). The CFD predictions are in quantitative agreement with the experimental data. The convective and diffusive contributions to the mass transfer of different flow patterns are analyzed. For all solvent pairs, the extraction efficiency varies irregularly with increasing flow rate due to changes in the mass transfer mechanism caused by a transition between flow regimes. Overall, we demonstrate >90% extraction efficiencies with high volumetric mass transfer coefficients ranging from 0.006 to 2.17 s–1. Furthermore, a merit index is defined to assess the trade-off between the fast mass transfer and the pressure drop in biphasic microchannels. In general, the mass transfer rate increases significantly at high flow rates at the expense of a high-pressure drop. Furthermore, the ethyl acetate/water irregular flow pattern is optimal due to a large throughput, extraction efficiency, and mass transfer coefficient, with a minimal pressure drop.

View Accepted Manuscript (DOE)

Research Organization:: RAPID Manufacturing Institute, New York, NY (United States)

Sponsoring Organization:: USDOE Office of Energy Efficiency and Renewable Energy (EERE), Energy Efficiency Office. Advanced Materials & Manufacturing Technologies Office (AMMTO)

Grant/Contract Number:: EE0007888

OSTI ID:: 2007312

Alternate ID(s):: OSTI ID: 1848631

Journal Information:: Industrial and Engineering Chemistry Research, Journal Name: Industrial and Engineering Chemistry Research Journal Issue: 9 Vol. 60; ISSN 0888-5885

Publisher:: American Chemical Society (ACS)Copyright Statement

Country of Publication:: United States

Language:: English

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