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Title: Apparatus and method for performing microfluidic manipulations for chemical analysis and synthesis

Patent ·
OSTI ID:20014014

A microchip laboratory system and method proved fluid manipulations for a variety of applications, including sample injection for microchip chemical separations. The microchip is fabricated using standard photolithographic procedures and chemical wet etching, with the substrate and cover plate joined using direct bonding. Capillary electrophoresis and electrochromatography are performed in channels formed in the substrate. Analytes are loaded into a four-way intersection of channels by electrokinetically pumping the analyte through the intersection, followed by switching of the potentials to force an analyte plug into the separation channel.

Sponsoring Organization:
USDOE
DOE Contract Number:
AC05-84OR21400
OSTI ID:
20014014
Resource Relation:
Other Information: PBD: 4 Jan 2000
Country of Publication:
United States
Language:
English