High Activity and Selectivity for Catalytic Alkane–Alkene Transfer (De)hydrogenation by (tBuPPP)Ir and the Importance of Choice of a Sacrificial Hydrogen Acceptor

Gordon, Benjamin M.; Parihar, Ashish; Hasanayn, Faraj; Goldman, Alan S.

doi:10.1021/acs.organomet.2c00401

High Activity and Selectivity for Catalytic Alkane–Alkene Transfer (De)hydrogenation by (^tBuPPP)Ir and the Importance of Choice of a Sacrificial Hydrogen Acceptor

Journal Article · Wed Oct 12 00:00:00 EDT 2022 · Organometallics

DOI:https://doi.org/10.1021/acs.organomet.2c00401· OSTI ID:2001037

^[1]; Parihar, Ashish ^[2]; ^[3]; ^[2]

Rutgers, The State University of New Jersey, Piscataway, NJ (United States); Rutgers University, New Brunswick, NJ (USA)
Rutgers, The State University of New Jersey, Piscataway, NJ (United States)
American University of Beirut (Lebanon)

The triphosphorus-coordinating pincer iridium fragment (^tBuPPP)Ir was recently reported to be highly active for the catalytic dehydrogenation of n-alkanes. Dehydrogenation is calculated to be highly regioselective for the terminal position of n-alkanes. Here, the extremely high intermolecular selectivity observed in n-alkane/cycloalkane competition experiments supports the prediction of extremely high regioselectivity for dehydrogenation of n-alkanes. The use of sterically unhindered hydrogen acceptors is key to observing the high activity of the (^tBuPPP)Ir fragment. 4,4-Dimethylpent-1-ene (TBP) is found to be particularly convenient for this purpose. With the commonly used hydrogen acceptor 3,3-dimethylbut-1-ene (TBE), (^tBuPPP)Ir affords n-alkane dehydrogenation at a rate no different than that obtained with the well-known fragment (^iPrPCP)Ir. However, with the use of TBP as acceptor, (^tBuPPP)Ir shows much greater activity for n-alkane transfer dehydrogenation than previously reported catalysts, affording appreciable rates even at 50 °C, an unprecedentedly low temperature for catalytic alkane transfer dehydrogenation. Also critical to the identification of (^tBuPPP)Ir as a highly effective catalyst is the use of n-alkane substrate rather than the commonly used “model” dehydrogenation substrate, cyclooctane, with which dehydrogenation rates are much lower than those with n-alkanes.

View Accepted Manuscript (DOE)

Research Organization:: Rutgers University, New Brunswick, NJ (United States)

Sponsoring Organization:: USDOE Office of Science (SC), Basic Energy Sciences (BES)

Grant/Contract Number:: SC0020139

OSTI ID:: 2001037

Journal Information:: Organometallics, Journal Name: Organometallics Journal Issue: 22 Vol. 41; ISSN 0276-7333

Publisher:: American Chemical SocietyCopyright Statement

Country of Publication:: United States

Language:: English

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High Activity and Selectivity for Catalytic Alkane–Alkene Transfer (De)hydrogenation by (tBuPPP)Ir and the Importance of Choice of a Sacrificial Hydrogen Acceptor

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References (53)

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High Activity and Selectivity for Catalytic Alkane–Alkene Transfer (De)hydrogenation by (^tBuPPP)Ir and the Importance of Choice of a Sacrificial Hydrogen Acceptor