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Title: A method for depth-dose distribution measurements in tissue irradiated by a proton beam

Abstract

The use of protons and heavy ions for the treatment of malignant and non-malignant disease has aroused a growing interest in the last decade. The notable advantage of heavy charged particles over photons in external beam radiotherapy lies in the possibility of irradiating a small localized region within the body, keeping a low value for the entrance dose. Owing to this high disuniformity of energy deposition, an essential requirement for treatment planning is a precise evaluation of the spatial distribution of absorbed dose. The proposed method for depth-dose distribution measurements utilizes a chemical dosimeter (ferrous sulphate solution plus sulfuric acid and eventually xylenol orange) incorporated in a gelatine, whose role is the maintenance of spatial information. Ionizing radiation causes a variation in some parameters of the system such as the proton relaxation rates in the solution (measurable by NMR analysis) or the optical absorption of the gel in the visible spectrum (measurable by spectrophotometry).

Authors:
; ;  [1]
  1. Universita di Milano (Italy) [and others
Publication Date:
OSTI Identifier:
199712
Report Number(s):
CONF-941129-
TRN: 95:005652-0204
Resource Type:
Conference
Resource Relation:
Conference: 13. international conference on the application of accelerators in research and industry, Denton, TX (United States), 7-10 Nov 1994; Other Information: PBD: 1994; Related Information: Is Part Of Thirteenth international conference on the application of accelerators in research and industry; Duggan, J.L.; Morgan, I.L. [eds.]; PB: 201 p.
Country of Publication:
United States
Language:
English
Subject:
55 BIOLOGY AND MEDICINE, BASIC STUDIES; DEPTH DOSE DISTRIBUTIONS; MEASURING METHODS; RADIOTHERAPY; PROTONS; HEAVY IONS; CHEMICAL DOSEMETERS

Citation Formats

Gambarini, G., Birattari, C., and Bartolo, D. de. A method for depth-dose distribution measurements in tissue irradiated by a proton beam. United States: N. p., 1994. Web.
Gambarini, G., Birattari, C., & Bartolo, D. de. A method for depth-dose distribution measurements in tissue irradiated by a proton beam. United States.
Gambarini, G., Birattari, C., and Bartolo, D. de. Sat . "A method for depth-dose distribution measurements in tissue irradiated by a proton beam". United States.
@article{osti_199712,
title = {A method for depth-dose distribution measurements in tissue irradiated by a proton beam},
author = {Gambarini, G. and Birattari, C. and Bartolo, D. de},
abstractNote = {The use of protons and heavy ions for the treatment of malignant and non-malignant disease has aroused a growing interest in the last decade. The notable advantage of heavy charged particles over photons in external beam radiotherapy lies in the possibility of irradiating a small localized region within the body, keeping a low value for the entrance dose. Owing to this high disuniformity of energy deposition, an essential requirement for treatment planning is a precise evaluation of the spatial distribution of absorbed dose. The proposed method for depth-dose distribution measurements utilizes a chemical dosimeter (ferrous sulphate solution plus sulfuric acid and eventually xylenol orange) incorporated in a gelatine, whose role is the maintenance of spatial information. Ionizing radiation causes a variation in some parameters of the system such as the proton relaxation rates in the solution (measurable by NMR analysis) or the optical absorption of the gel in the visible spectrum (measurable by spectrophotometry).},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Sat Dec 31 00:00:00 EST 1994},
month = {Sat Dec 31 00:00:00 EST 1994}
}

Conference:
Other availability
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