PDB ‐101: Educational resources supporting molecular explorations through biology and medicine
[1];
[3];
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- Research Collaboratory for Structural Bioinformatics Protein Data Bank Rutgers, The State University of New Jersey Piscataway New Jersey USA, Institute for Quantitative Biomedicine Rutgers, The State University of New Jersey Piscataway New Jersey USA
- Research Collaboratory for Structural Bioinformatics Protein Data Bank Rutgers, The State University of New Jersey Piscataway New Jersey USA, Institute for Quantitative Biomedicine Rutgers, The State University of New Jersey Piscataway New Jersey USA, Rutgers Cancer Institute of New Jersey Rutgers, The State University of New Jersey New Brunswick New Jersey USA
- Research Collaboratory for Structural Bioinformatics Protein Data Bank Rutgers, The State University of New Jersey Piscataway New Jersey USA, Institute for Quantitative Biomedicine Rutgers, The State University of New Jersey Piscataway New Jersey USA, Rutgers Cancer Institute of New Jersey Rutgers, The State University of New Jersey New Brunswick New Jersey USA, Department of Integrative Structural and Computational Biology The Scripps Research Institute La Jolla California USA
- Research Collaboratory for Structural Bioinformatics Protein Data Bank Rutgers, The State University of New Jersey Piscataway New Jersey USA, Institute for Quantitative Biomedicine Rutgers, The State University of New Jersey Piscataway New Jersey USA, Rutgers Cancer Institute of New Jersey Rutgers, The State University of New Jersey New Brunswick New Jersey USA, Research Collaboratory for Structural Bioinformatics Protein Data Bank, San Diego Supercomputer Center University of California San Diego La Jolla California USA, Department of Chemistry and Chemical Biology Rutgers, The State University of New Jersey Piscataway New Jersey USA
Abstract The Protein Data Bank (PDB) archive is a rich source of information in the form of atomic‐level three‐dimensional (3D) structures of biomolecules experimentally determined using macromolecular crystallography, nuclear magnetic resonance (NMR) spectroscopy, and electron microscopy (3DEM). Originally established in 1971 as a resource for protein crystallographers to freely exchange data, today PDB data drive research and education across scientific disciplines. In 2011, the online portal PDB‐101 was launched to support teachers, students, and the general public in PDB archive exploration ( pdb101.rcsb.org ). Maintained by the Research Collaboratory for Structural Bioinformatics PDB, PDB‐101 aims to help train the next generation of PDB users and to promote the overall importance of structural biology and protein science to nonexperts. Regularly published features include the highly popular Molecule of the Month series, 3D model activities, molecular animation videos, and educational curricula. Materials are organized into various categories (Health and Disease, Molecules of Life, Biotech and Nanotech, and Structures and Structure Determination) and searchable by keyword. A biennial health focus frames new resource creation and provides topics for annual video challenges for high school students. Web analytics document that PDB‐101 materials relating to fundamental topics (e.g., hemoglobin, catalase) are highly accessed year‐on‐year. In addition, PDB‐101 materials created in response to topical health matters (e.g., Zika, measles, coronavirus) are well received. PDB‐101 shows how learning about the diverse shapes and functions of PDB structures promotes understanding of all aspects of biology, from the central dogma of biology to health and disease to biological energy.
- Sponsoring Organization:
- USDOE
- OSTI ID:
- 1997062
- Journal Information:
- Protein Science, Journal Name: Protein Science Vol. 31 Journal Issue: 1; ISSN 0961-8368
- Publisher:
- Wiley Blackwell (John Wiley & Sons)Copyright Statement
- Country of Publication:
- United Kingdom
- Language:
- English
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