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Fundamentals of bio-electrochemical sensing

Journal Article · · Chemical Engineering Journal Advances
 [1];  [2];  [2];  [3];  [4]
  1. KLE Technological University (India)
  2. St. Joseph’s College (India)
  3. Oak Ridge National Laboratory (ORNL), Oak Ridge, TN (United States); Idaho National Laboratory (INL), Idaho Falls, ID (United States); Idaho State Univ., Pocatello, ID (United States)
  4. KLE Technological University (India); Chandigarh University (India)

The utilization of bio-functionalities such as biorecognition or catalysis derived them their name biosensors. Bio-electrochemical sensing is a new discipline that combines the advantages of biological detection and electrochemical transduction. Bio-electrochemical sensors are devices that use biological materials such as enzymes, antibodies, DNA, or cells as receptors to detect target analytes in a variety of samples. Electrodes convert biological interactions into electrical impulses, which can be studied using various electrochemical techniques. Bio-electrochemical sensors have demonstrated significant promise for use in clinical diagnostics, environmental monitoring, food safety, and biotechnology. Biosensors have received numerous applications in recent years because they are fast, simple, and inexpensive for practical applications. In this article, we cover the basic principles, design strategies, immobilization and regeneration techniques, along with the advantages and applications of bio-electrochemical sensors. Finally, this article discusses the rationale for developing electrochemical biosensors in the context of the various bio-receptors that can be applied.

Research Organization:
Oak Ridge National Laboratory (ORNL), Oak Ridge, TN (United States)
Sponsoring Organization:
USDOE Office of Science (SC)
Grant/Contract Number:
AC05-00OR22725
OSTI ID:
1995654
Alternate ID(s):
OSTI ID: 1995993
Journal Information:
Chemical Engineering Journal Advances, Journal Name: Chemical Engineering Journal Advances Vol. 16; ISSN 2666-8211
Publisher:
ElsevierCopyright Statement
Country of Publication:
United States
Language:
English

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