A network analysis of the long-term quality of life and mental distress of COVID-19 survivors 1 year after hospital discharge

Peng, Pu; Wang, Yaqi; Li, Zhuqing; Zhou, Yanan; Wang, Ji; Qu, Miao; Liu, Tieqiao

doi:10.3389/fpubh.2023.1223429

A network analysis of the long-term quality of life and mental distress of COVID-19 survivors 1 year after hospital discharge

Journal Article · Fri Jul 28 00:00:00 EDT 2023 · Frontiers in Public Health

DOI:https://doi.org/10.3389/fpubh.2023.1223429· OSTI ID:1992959

Peng, Pu; Wang, Yaqi; Li, Zhuqing; Zhou, Yanan; Wang, Ji; Qu, Miao; Liu, Tieqiao

Objectives

COVID-19 survivors suffer from persistent mental distress and impaired quality of life (QOL) after recovery from the infection. However, the symptom-symptom interaction between these psychological variables remained unexplored. The present study aimed to determine the symptom network of mental distress (depression, anxiety, sleep disturbance, fatigue, and post-traumatic stress disorder) and their association with QOL among 535 COVID-19 survivors 1 year after hospital discharge.

Methods

9-item Patient Health Questionnaire, 7-item Generalized Anxiety Disorder Scale, Chalder fatigue scale, Impact of Event Scale-Revised, Pittsburgh Sleep Quality Index, and 36-Item Short-Form Health Survey were applied to measure depression, anxiety, fatigue, PTSD, sleep disturbances, and QOL, respectively. Two networks were estimated using Gaussian graphical model. Network 1 consisted of mental symptoms to determine the central and bridge symptoms. Network 2 additionally included QOL to determine which mental symptoms were mostly related to QOL.

Results

60% of the COVID-19 survivors experienced mental distress 1 year after hospital discharge. Uncontrollable and excessive worry, psychomotor symptoms, intrusion, and daytime dysfunction were the most central symptoms. Daytime dysfunction and fatigue (especially mental fatigue and loss of energy) served as the bridge symptoms across the mental distress network and exhibited the most substantial association with QOL.

Conclusion

Our study demonstrated several key symptoms that played a vital role in mental distress and QOL among COVID-19 survivors. Prompt screening and targeted interventions for these symptoms might hold great promise in preventing mental distress and improving QOL in COVID-19 survivors.

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Sponsoring Organization:: USDOE Office of Electricity (OE), Advanced Grid Research & Development. Power Systems Engineering Research

OSTI ID:: 1992959

Journal Information:: Frontiers in Public Health, Journal Name: Frontiers in Public Health Vol. 11; ISSN 2296-2565

Publisher:: Frontiers Media SACopyright Statement

Country of Publication:: Switzerland

Language:: English

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