Thermodynamic Coupling Function Analysis of Allosteric Mechanisms in the Human Dopamine Transporter
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January 2018 |
Gating mechanism of the extracellular entry to the lipid pathway in a TMEM16 scramblase
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August 2018 |
Dynamic modulation of the lipid translocation groove generates a conductive ion channel in Ca2+-bound nhTMEM16
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October 2019 |
A note on two problems in connexion with graphs
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December 1959 |
Membrane lipids are both the substrates and a mechanistically responsive environment of TMEM16 scramblase proteins
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November 2019 |
Gain of function of TMEM16E/ANO5 scrambling activity caused by a mutation associated with gnathodiaphyseal dysplasia
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November 2017 |
Identification of a lipid scrambling domain in ANO6/TMEM16F
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June 2015 |
The Allostery Landscape: Quantifying Thermodynamic Couplings in Biomolecular Systems
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November 2016 |
Scalable molecular dynamics on CPU and GPU architectures with NAMD
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July 2020 |
Robust Perron cluster analysis in conformation dynamics
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March 2005 |
Lifting the veils on TMEM16E function
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January 2019 |
Out-of-the-groove transport of lipids by TMEM16 and GPCR scramblases
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June 2018 |
TMEM16 scramblases thin the membrane to enable lipid scrambling
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May 2022 |
ANO10 mutations cause ataxia and coenzyme Q10 deficiency
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September 2014 |
MSMBuilder: Statistical Models for Biomolecular Dynamics
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January 2017 |
The nhTMEM16 Scramblase Is Also a Nonselective Ion Channel
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November 2016 |
Compound heterozygosity for 2 novel TMEM16F mutations in a patient with Scott syndrome
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April 2011 |
Cryo-EM Studies of TMEM16F Calcium-Activated Ion Channel Suggest Features Important for Lipid Scrambling
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July 2019 |
Cellular defects by deletion of ANO10 are due to deregulated local calcium signaling
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January 2017 |
Comparative Protein Structure Modeling Using MODELLER
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November 2016 |
Defective membrane fusion and repair inAnoctamin5-deficient muscular dystrophy
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February 2016 |
Three novel ANO5 missense mutations in Caucasian and Chinese families and sporadic cases with gnathodiaphyseal dysplasia
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February 2017 |
MSMBuilder2: Modeling Conformational Dynamics on the Picosecond to Millisecond Scale
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August 2011 |
CHARMM36m: an improved force field for folded and intrinsically disordered proteins
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November 2016 |
PyEMMA 2: A Software Package for Estimation, Validation, and Analysis of Markov Models
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October 2015 |
A TMEM16F point mutation causes an absence of canine platelet TMEM16F and ineffective activation and death‐induced phospholipid scrambling
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December 2015 |
Atomistic insight into lipid translocation by a TMEM16 scramblase
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November 2016 |
Mechanisms of Lipid Scrambling by the G Protein-Coupled Receptor Opsin
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February 2018 |
CHARMM-GUI Membrane Builder for Mixed Bilayers and Its Application to Yeast Membranes
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July 2009 |
An Additional Ca2+ Binding Site Allosterically Controls TMEM16A Activation
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December 2020 |
Characterization of the scrambling domain of the TMEM16 family
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May 2017 |
PROPKA3: Consistent Treatment of Internal and Surface Residues in Empirical p K a Predictions
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December 2010 |
Structural basis of Ca2+-dependent activation and lipid transport by a TMEM16 scramblase
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January 2019 |
Lipid flippases and their biological functions
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November 2006 |
A founder mutation in Anoctamin 5 is a major cause of limb girdle muscular dystrophy
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December 2010 |
Anoctamins/TMEM16 Proteins: Chloride Channels Flirting with Lipids and Extracellular Vesicles
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February 2017 |
Lipids and ions traverse the membrane by the same physical pathway in the nhTMEM16 scramblase
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September 2017 |
An inner activation gate controls TMEM16F phospholipid scrambling
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April 2019 |
X-ray structure of a calcium-activated TMEM16 lipid scramblase
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November 2014 |
The structural basis of lipid scrambling and inactivation in the endoplasmic reticulum scramblase TMEM16K
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September 2019 |
Autosomal Recessive Cerebellar Ataxia Type 3 Due toANO10Mutations
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October 2014 |
MemProtMD: Automated Insertion of Membrane Protein Structures into Explicit Lipid Membranes
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July 2015 |
Macromolecular Modeling with Rosetta
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June 2008 |
Simulations of Anionic Lipid Membranes: Development of Interaction-Specific Ion Parameters and Validation Using NMR Data
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August 2013 |
Ion channel and lipid scramblase activity associated with expression of TMEM16F/ANO6 isoforms: TMEM16F variants
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July 2015 |
NbIT - A New Information Theory-Based Analysis of Allosteric Mechanisms Reveals Residues that Underlie Function in the Leucine Transporter LeuT
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May 2014 |
Phospholipid Scrambling Activity by TMEM16E/Ano5: Opposite Effects of Mutations Causing Bone Dysplasia and Muscular Dystrophy
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February 2019 |
Platelet membrane phospholipid asymmetry: from the characterization of a scramblase activity to the identification of an essential protein mutated in Scott syndrome: Platelet phospholipid scramblase
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September 2011 |
A novel missense mutation in ANO5/TMEM16E is causative for gnathodiaphyseal dyplasia in a large Italian pedigree
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October 2012 |
ANO10 c.1150_1151del is a founder mutation causing autosomal recessive cerebellar ataxia in Roma/Gypsies
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October 2011 |
Stepwise activation mechanism of the scramblase nhTMEM16 revealed by cryo-EM
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February 2019 |
Cryo-EM structures and functional characterization of the murine lipid scramblase TMEM16F
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February 2019 |
The permeation of potassium ions through the lipid scrambling path of the membrane protein nhTMEM16
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July 2022 |
Recessive Mutations in the Putative Calcium-Activated Chloride Channel Anoctamin 5 Cause Proximal LGMD2L and Distal MMD3 Muscular Dystrophies
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February 2010 |
Targeted Next-Generation Sequencing of a 12.5 Mb Homozygous Region Reveals ANO10 Mutations in Patients with Autosomal-Recessive Cerebellar Ataxia
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December 2010 |
Ca2+-dependent phospholipid scrambling by a reconstituted TMEM16 ion channel
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September 2013 |
The Novel Gene Encoding a Putative Transmembrane Protein Is Mutated in Gnathodiaphyseal Dysplasia (GDD)
- Tsutsumi, Satoshi; Kamata, Nobuyuki; Vokes, Tamara J.
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The American Journal of Human Genetics, Vol. 74, Issue 6, p. 1255-1261
https://doi.org/10.1086/421527
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June 2004 |
Calcium-dependent phospholipid scrambling by TMEM16F
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November 2010 |
OpenMM 7: Rapid development of high performance algorithms for molecular dynamics
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July 2017 |
Identification of slow molecular order parameters for Markov model construction
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July 2013 |
A Markov State-based Quantitative Kinetic Model of Sodium Release from the Dopamine Transporter
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January 2017 |
Known structures and unknown mechanisms of TMEM16 scramblases and channels
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June 2018 |