Skip to main content
U.S. Department of Energy
Office of Scientific and Technical Information

Structure and Function of the β-Asp-Arg Polymerase Cyanophycin Synthetase 2

Journal Article · · ACS Chemical Biology
 [1];  [2];  [2];  [1]
  1. Department of Biochemistry and Centre de recherche en biologie structurale, McGill University, Montréal H3G 0B1, Quebec, Canada
  2. Laboratory of Organic Chemistry, ETH Zürich, CH-8093 Zürich, Switzerland
Not provided.
Research Organization:
USDOE Joint Genome Institute (JGI), Walnut Creek, CA (United States)
Sponsoring Organization:
USDOE
DOE Contract Number:
AC02-05CH11231
OSTI ID:
1982015
Journal Information:
ACS Chemical Biology, Journal Name: ACS Chemical Biology Journal Issue: 3 Vol. 17; ISSN 1554-8929
Publisher:
American Chemical Society (ACS)
Country of Publication:
United States
Language:
English

References (37)

Glutathione Biosynthesis in Bacteria by Bifunctional GshF Is Driven by a Modular Structure Featuring a Novel Hybrid ATP-Grasp Fold journal March 2012
High-Resolution Comparative Modeling with RosettaCM journal October 2013
Scaling diffraction data in the DIALS software package: algorithms and new approaches for multi-crystal scaling journal March 2020
CphA2 is a novel type of cyanophycin synthetase in N2-fixing cyanobacteria journal March 2016
Wound Healing Attributes of Polyelectrolyte Multilayers Prepared with Multi‐ l ‐arginyl‐poly‐ l ‐aspartate Pairing with Hyaluronic Acid and γ‐Polyglutamic Acid journal June 2020
The ATP-grasp enzymes journal December 2011
Establishment of Cyanophycin Biosynthesis in Pichia pastoris and Optimization by Use of Engineered Cyanophycin Synthetases journal February 2010
Nitrogen-regulated Genes for the Metabolism of Cyanophycin, a Bacterial Nitrogen Reserve Polymer journal March 2004
The Phenix software for automated determination of macromolecular structures journal September 2011
The evolutionary diversification of cyanobacteria: Molecular-phylogenetic and paleontological perspectives journal March 2006
Three-dimensional Structure of the Glutathione Synthetase from Escherichia coli B at 2·0 Å Resolution journal February 1993
Oxygen relations of nitrogen fixation in cyanobacteria journal June 1992
A cyanophycin synthetase from Thermosynechococcus elongatus BP-1 catalyzes primer-independent cyanophycin synthesis journal November 2008
Tobacco as platform for a commercial production of cyanophycin journal December 2016
Cell Penetration, Herbicidal Activity, and in-vivo -Toxicity of Oligo-Arginine Derivatives and of Novel Guanidinium-Rich Compounds Derived from the Biopolymer Cyanophycin journal October 2018
WebLogo: A Sequence Logo Generator journal May 2004
Coot model-building tools for molecular graphics journal November 2004
Automated refinement of macromolecular structures at low resolution using prior information journal September 2016
Biosynthesis of the cyanobacterial reserve polymer multi-L-arginyl-poly-L-aspartic acid (cyanophycin): Mechanism of the cyanophycin synthetase reaction studied with synthetic primers journal September 2000
Assessment of technological options and economical feasibility for cyanophycin biopolymer and high-value amino acid production journal September 2007
Compartmentalized cyanophycin metabolism in the diazotrophic filaments of a heterocyst-forming cyanobacterium journal February 2014
Effect of the Nitrogen Source on Phycobiliprotein Synthesis and Cell Reserves in A Chromatically Adapting Filamentous Cyanobacterium journal March 1996
Structural Basis for Evolution of Product Diversity in Soybean Glutathione Biosynthesis journal November 2009
The biosynthesis of multi-l-arginyl-poly(l-aspartic acid) in the filamentous cyanobacterium Anabaena cylindrica journal February 1976
Structure ofD-alanine-D-alanine ligase fromThermus thermophilusHB8: cumulative conformational change and enzyme–ligand interactions journal September 2009
Structural and functional modularity of proteins in the de novo purine biosynthetic pathway journal May 2009
Pattern of cyanophycin accumulation in nitrogen-fixing and non-nitrogen-fixing cyanobacteria journal July 2001
Structure of the multifunctional loops in the nonclassical ATP-binding fold of glutathione synthetase journal January 1996
Isolation of Cyanophycin-degrading Bacteria, Cloning and Characterization of an Extracellular Cyanophycinase Gene (cphE) from Pseudomonas anguilliseptica Strain BI journal July 2002
Structures and function of the amino acid polymerase cyanophycin synthetase journal August 2021
A Pseudo-Michaelis Quaternary Complex in the Reverse Reaction of a Ligase:  Structure of Escherichia coli B Glutathione Synthetase Complexed with ADP, Glutathione, and Sulfate at 2.0 Å Resolution , journal January 1996
Syntheses of Cyanophycin Segments for Investigations of Cell-Penetration journal June 2018
Cyanophycin Mediates the Accumulation and Storage of Fixed Carbon in Non-Heterocystous Filamentous Cyanobacteria from Coniform Mats journal February 2014
Cyanophycin Synthesis Optimizes Nitrogen Utilization in the Unicellular Cyanobacterium Synechocystis sp. Strain PCC 6803 journal October 2018
CCP 4 i 2: the new graphical user interface to the CCP 4 program suite journal February 2018
Analysis of Genome Sequences for Genes of Cyanophycin Metabolism: Identifying Putative Cyanophycin Metabolizing Prokaryotes journal March 2007
Cyanophycin Production in a Phycoerythrin-Containing Marine Synechococcus Strain of Unusual Phylogenetic Affinity journal April 2002

Similar Records

Structures and function of the amino acid polymerase cyanophycin synthetase
Journal Article · 2021 · Nat. Chem. Biol. · OSTI ID:1831268

A cryptic third active site in cyanophycin synthetase creates primers for polymerization
Journal Article · 2022 · Nature Communications · OSTI ID:1904103

Structures of SAICAR synthetase (PurC) from Streptococcus pneumoniae with ADP, Mg[superscript 2+], AIR and Asp
Journal Article · 2014 · Acta Crystallogr. D · OSTI ID:1140036