Use of the cavity-to-myocardial count ratio with Tc-99m sestamibi myocardial perfusion SPECT to predict reduced left ventricular function

Journal Article · Sun May 01 00:00:00 EDT 1994 · Journal of Nuclear Medicine

OSTI ID:197938

Heerden, B.B. van; Heerden, P D.R. van; Wasserman, H J ^[1]

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1. Tygerberg Hospital (South Africa)

In patients with left ventricular dysfunction, the left ventricular cavity appears abnormally photopenic on SPECT images, both with T1-201 and Tc-99m sestamibi showed a linear correlation between the cavity-to-myocardial count ratio (C/M ratio) and left ventricular ejection fraction (LVEF) with T1-201 SPECT. Using an exercise ratio of 0.4 as the lower limit of normal, they could predict a reduced LVEF with a sensitivity of 83% and specificity of 78%. The purpose of our study was to ascertain whether the C/M ratio could also be used as an indicator of LVEF when using Tc-99m sestamibi as imaging agent.

• OSTI ID: 197938
• Report Number(s): CONF-940605--
• Journal Information: Journal of Nuclear Medicine, Journal Name: Journal of Nuclear Medicine Journal Issue: Suppl.5 Vol. 35; ISSN JNMEAQ; ISSN 0161-5505
• Country of Publication: United States
• Language: English

Related Subjects

55 BIOLOGY AND MEDICINE
BASIC STUDIES
ACCURACY
IMAGES
MYOCARDIUM
PATIENTS
REGRESSION ANALYSIS
SENSITIVITY
SINGLE PHOTON EMISSION COMPUTED TOMOGRAPHY
TECHNETIUM 99
THALLIUM 201