Probing molecular vibrations by monochromated electron microscopy

Yan, Xingxu; Gadre, Chaitanya A.; Aoki, Toshihiro; Pan, Xiaoqing

doi:10.1016/j.trechm.2021.10.004

Probing molecular vibrations by monochromated electron microscopy

Journal Article · Tue Nov 09 00:00:00 EST 2021 · Trends in Chemistry

DOI:https://doi.org/10.1016/j.trechm.2021.10.004· OSTI ID:1977697

Yan, Xingxu ^[1]; Gadre, Chaitanya A. ^[2]; Aoki, Toshihiro ^[2]; ^[2]

University of California, Irvine, CA (United States); OSTI
University of California, Irvine, CA (United States)

Chemical bonds fundamentally determine molecular properties and are prevalently characterized by various spectroscopic means such as infrared and Raman spectroscopies. However, the spatial resolution of these conventional approaches is insufficient to reveal nanoscale features. Recently, monochromated electron energy-loss spectroscopy (EELS) in the transmission electron microscope achieved a groundbreaking energy resolution of a few millielectronvolts and enabled direct observation of molecular vibrational spectrum with unmatched spatial resolution. Vibrational EELS is widely applicable to both organic and inorganic matter in the solid state or liquid phase. In this study, we introduce recent advancements and key concepts of this method, compare with other spectroscopic techniques, and discuss future developments for potential applications in research fields centered on catalysts, polymers, and live cells.

View Accepted Manuscript (DOE)

Research Organization:: University of California, Irvine, CA (United States)

Sponsoring Organization:: USDOE Office of Science (SC), Basic Energy Sciences (BES); USDOE Office of Science (SC), Basic Energy Sciences (BES). Materials Sciences & Engineering Division (MSE)

Grant/Contract Number:: SC0014430

OSTI ID:: 1977697

Alternate ID(s):: OSTI ID: 1837335

Journal Information:: Trends in Chemistry, Journal Name: Trends in Chemistry Journal Issue: 1 Vol. 4; ISSN 2589-5974

Publisher:: ElsevierCopyright Statement

Country of Publication:: United States

Language:: English

References (101)

Vibrational Spectroscopy of Water with High Spatial Resolution Jokisaari, Jacob R.; Hachtel, Jordan A.; Hu, Xuan Advanced Materials, Vol. 30, Issue 36 https://doi.org/10.1002/adma.201802702	journal	July 2018
Quantitative electron energy loss spectroscopy in biology Leapman, R. D.; Ornberg, R. L. Ultramicroscopy, Vol. 24, Issue 2-3 https://doi.org/10.1016/0304-3991(88)90314-2	journal	January 1988
Simulating high-angle annular dark-field stem images including inelastic thermal diffuse scattering Wang, Z. L.; Cowley, J. M. Ultramicroscopy, Vol. 31, Issue 4 https://doi.org/10.1016/0304-3991(89)90340-9	journal	December 1989
Simulation of thermal diffuse scattering including a detailed phonon dispersion curve A. Muller, David; Edwards, Byard; J. Kirkland, Earl Ultramicroscopy, Vol. 86, Issue 3-4 https://doi.org/10.1016/S0304-3991(00)00128-5	journal	February 2001
Measurement of Coulomb interactions in an electron beam monochromator Tiemeijer, P. C. Ultramicroscopy, Vol. 78, Issue 1-4 https://doi.org/10.1016/S0304-3991(99)00027-3	journal	June 1999
Effect of carbon nanofiber surface functional groups on oxygen reduction in alkaline solution Zhong, Ren-Sheng; Qin, Yuan-Hang; Niu, Dong-Fang Journal of Power Sources, Vol. 225 https://doi.org/10.1016/j.jpowsour.2012.10.043	journal	March 2013
Advantages of a monochromator for bandgap measurements using electron energy-loss spectroscopy Kimoto, Koji; Kothleitner, Gerald; Grogger, Werner Micron, Vol. 36, Issue 2 https://doi.org/10.1016/j.micron.2004.11.001	journal	February 2005
Electrocatalysis enhancement of iron-based catalysts induced by synergy of methanol and oxygen-containing groups Yan, Xingxu; Tang, Zhenkun; Xu, Xin Nano Energy, Vol. 21 https://doi.org/10.1016/j.nanoen.2016.01.030	journal	March 2016
The micro-setup for neutron imaging: A major step forward to improve the spatial resolution Lehmann, E. H.; Frei, G.; Kühne, G. Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, Vol. 576, Issue 2-3 https://doi.org/10.1016/j.nima.2007.03.017	journal	June 2007
Statistical consequences of applying a PCA noise filter on EELS spectrum images Lichtert, Stijn; Verbeeck, Jo Ultramicroscopy, Vol. 125 https://doi.org/10.1016/j.ultramic.2012.10.001	journal	February 2013
Vibrational-loss EELS and the avoidance of radiation damage Egerton, R. F. Ultramicroscopy, Vol. 159 https://doi.org/10.1016/j.ultramic.2015.08.003	journal	December 2015
Detection of water and its derivatives on individual nanoparticles using vibrational electron energy-loss spectroscopy Crozier, Peter A.; Aoki, Toshihiro; Liu, Qianlang Ultramicroscopy, Vol. 169 https://doi.org/10.1016/j.ultramic.2016.06.008	journal	October 2016
Optimization of monochromated TEM for ultimate resolution imaging and ultrahigh resolution electron energy loss spectroscopy Lopatin, Sergei; Cheng, Bin; Liu, Wei-Ting Ultramicroscopy, Vol. 184 https://doi.org/10.1016/j.ultramic.2017.08.016	journal	January 2018
Spatial and spectral dynamics in STEM hyperspectral imaging using random scan patterns Zobelli, Alberto; Woo, Steffi Y.; Tararan, Anna Ultramicroscopy, Vol. 212 https://doi.org/10.1016/j.ultramic.2019.112912	journal	May 2020
Hybrid pixel direct detector for electron energy loss spectroscopy Plotkin-Swing, Benjamin; Corbin, George J.; De Carlo, Sacha Ultramicroscopy, Vol. 217 https://doi.org/10.1016/j.ultramic.2020.113067	journal	October 2020
Prospects for Vibrational-Mode EELS with High Spatial Resolution Egerton, R. F. Microscopy and Microanalysis, Vol. 20, Issue 3 https://doi.org/10.1017/S1431927613014013	journal	February 2014
Is Localized Infrared Spectroscopy Now Possible in the Electron Microscope? Rez, Peter Microscopy and Microanalysis, Vol. 20, Issue 3 https://doi.org/10.1017/S1431927614000129	journal	March 2014
Damage-free Analysis of Biological Materials by Vibrational Spectroscopy in the EM Krivanek, Ondrej; Dohnalkova, Alice; Kochovski, Zdravko Microscopy and Microanalysis, Vol. 26, Issue S2 https://doi.org/10.1017/S1431927620013409	journal	July 2020
Ultra-high Energy Resolution EELS Dellby, Niklas; Lovejoy, Tracy; Corbin, George Microscopy and Microanalysis, Vol. 26, Issue S2 https://doi.org/10.1017/S1431927620019406	journal	July 2020
Role of Convergence and Collection Angles in the Excitation of Long- and Short-Wavelength Phonons with Vibrational Electron Energy-Loss Spectroscopy Venkatraman, Kartik; Crozier, Peter A. Microscopy and Microanalysis, Vol. 27, Issue 5 https://doi.org/10.1017/S1431927621012034	journal	June 2021
Isotope-Resolved Electron Energy Loss Spectroscopy in a Monochromated Scanning Transmission Electron Microscope Hachtel, Jordan A.; Jokisaari, Jacob R.; Krivanek, Ondrej L. Microscopy Today, Vol. 29, Issue 1 https://doi.org/10.1017/S1551929520001789	journal	January 2021
AFM-IR: Technology and Applications in Nanoscale Infrared Spectroscopy and Chemical Imaging Dazzi, Alexandre; Prater, Craig B. Chemical Reviews, Vol. 117, Issue 7 https://doi.org/10.1021/acs.chemrev.6b00448	journal	December 2016
Tip-Enhanced Raman Spectroscopy: Technique and Recent Advances Verma, Prabhat Chemical Reviews, Vol. 117, Issue 9 https://doi.org/10.1021/acs.chemrev.6b00821	journal	April 2017
Nanoimaging of Orientational Defects in Semiconducting Organic Films Mrkyvkova, Nada; Cernescu, Adrian; Futera, Zdenek The Journal of Physical Chemistry C, Vol. 125, Issue 17 https://doi.org/10.1021/acs.jpcc.1c00059	journal	April 2021
Monolayer to Bulk Properties of Hexagonal Boron Nitride Wickramaratne, Darshana; Weston, Leigh; Van de Walle, Chris G. The Journal of Physical Chemistry C, Vol. 122, Issue 44 https://doi.org/10.1021/acs.jpcc.8b09087	journal	October 2018
Direct in Situ Observation and Analysis of the Formation of Palladium Nanocrystals with High-Index Facets Gao, Wenpei; Hou, Yusheng; Hood, Zachary D. Nano Letters, Vol. 18, Issue 11 https://doi.org/10.1021/acs.nanolett.8b02953	journal	October 2018
Unexpected Strong Thermally Induced Phonon Energy Shift for Mapping Local Temperature Yan, Xingxu; Liu, Chengyan; Gadre, Chaitanya A. Nano Letters, Vol. 19, Issue 10 https://doi.org/10.1021/acs.nanolett.9b03307	journal	September 2019
Functional Group Mapping by Electron Beam Vibrational Spectroscopy from Nanoscale Volumes Collins, Sean M.; Kepaptsoglou, Demie M.; Hou, Jingwei Nano Letters, Vol. 20, Issue 2 https://doi.org/10.1021/acs.nanolett.9b04732	journal	December 2019
Real-Space Mapping of Oxygen Coordination in Phase-Separated Aluminosilicate Glass: Implication for Glass Stability Liao, Kunyen; Haruta, Mitsutaka; Masuno, Atsunobu ACS Applied Nano Materials, Vol. 3, Issue 6 https://doi.org/10.1021/acsanm.0c00196	journal	June 2020
Theory of Atomic-Scale Vibrational Mapping and Isotope Identification with Electron Beams Konečná, Andrea; Iyikanat, Fadil; García de Abajo, F. Javier ACS Nano, Vol. 15, Issue 6 https://doi.org/10.1021/acsnano.1c01071	journal	May 2021
Graphene-Based Platform for Infrared Near-Field Nanospectroscopy of Water and Biological Materials in an Aqueous Environment Khatib, Omar; Wood, Joshua D.; McLeod, Alexander S. ACS Nano, Vol. 9, Issue 8 https://doi.org/10.1021/acsnano.5b01184	journal	July 2015
Local Plasmon Engineering in Doped Graphene Hage, Fredrik Sydow; Hardcastle, Trevor P.; Gjerding, Morten N. ACS Nano, Vol. 12, Issue 2 https://doi.org/10.1021/acsnano.7b08650	journal	February 2018
Nanoscale Probing of Local Hydrogen Heterogeneity in Disordered Carbon Nitrides with Vibrational Electron Energy-Loss Spectroscopy Haiber, Diane M.; Crozier, Peter A. ACS Nano, Vol. 12, Issue 6 https://doi.org/10.1021/acsnano.8b00884	journal	May 2018
Quantitative and Atomic-Scale View of CO-Induced Pt Nanoparticle Surface Reconstruction at Saturation Coverage via DFT Calculations Coupled with in Situ TEM and IR Avanesian, Talin; Dai, Sheng; Kale, Matthew J. Journal of the American Chemical Society, Vol. 139, Issue 12 https://doi.org/10.1021/jacs.7b01081	journal	March 2017
Spatially Resolved Raman Spectroscopy of Single- and Few-Layer Graphene Graf, D.; Molitor, F.; Ensslin, K. Nano Letters, Vol. 7, Issue 2, p. 238-242 https://doi.org/10.1021/nl061702a	journal	February 2007
Vibrational spectroscopy in the electron microscope Krivanek, Ondrej L.; Lovejoy, Tracy C.; Dellby, Niklas Nature, Vol. 514, Issue 7521 https://doi.org/10.1038/nature13870	journal	October 2014
Damage-free vibrational spectroscopy of biological materials in the electron microscope Rez, Peter; Aoki, Toshihiro; March, Katia Nature Communications, Vol. 7, Issue 1 https://doi.org/10.1038/ncomms10945	journal	March 2016
Rational design of carbon nitride photocatalysts by identification of cyanamide defects as catalytically relevant sites Lau, Vincent Wing-hei; Moudrakovski, Igor; Botari, Tiago Nature Communications, Vol. 7, Issue 1 https://doi.org/10.1038/ncomms12165	journal	July 2016
Van der Waals pressure and its effect on trapped interlayer molecules Vasu, K. S.; Prestat, E.; Abraham, J. Nature Communications, Vol. 7, Issue 1 https://doi.org/10.1038/ncomms12168	journal	July 2016
Nanoscale measurements of unoccupied band dispersion in few-layer graphene Jobst, Johannes; Kautz, Jaap; Geelen, Daniël Nature Communications, Vol. 6, Issue 1 https://doi.org/10.1038/ncomms9926	journal	November 2015
Electron counting and beam-induced motion correction enable near-atomic-resolution single-particle cryo-EM Li, Xueming; Mooney, Paul; Zheng, Shawn Nature Methods, Vol. 10, Issue 6 https://doi.org/10.1038/nmeth.2472	journal	May 2013
Probing low-energy hyperbolic polaritons in van der Waals crystals with an electron microscope Govyadinov, Alexander A.; Konečná, Andrea; Chuvilin, Andrey Nature Communications, Vol. 8, Issue 1 https://doi.org/10.1038/s41467-017-00056-y	journal	July 2017
Subsurface chemical nanoidentification by nano-FTIR spectroscopy Mester, Lars; Govyadinov, Alexander A.; Chen, Shu Nature Communications, Vol. 11, Issue 1 https://doi.org/10.1038/s41467-020-17034-6	journal	July 2020
Four-dimensional vibrational spectroscopy for nanoscale mapping of phonon dispersion in BN nanotubes Qi, Ruishi; Li, Ning; Du, Jinlong Nature Communications, Vol. 12, Issue 1 https://doi.org/10.1038/s41467-021-21452-5	journal	February 2021
Liquid–liquid phase separation during amphiphilic self-assembly Ianiro, Alessandro; Wu, Hanglong; van Rijt, Mark M. J. Nature Chemistry, Vol. 11, Issue 4 https://doi.org/10.1038/s41557-019-0210-4	journal	February 2019
Imaging defects and their evolution in a metal–organic framework at sub-unit-cell resolution Liu, Lingmei; Chen, Zhijie; Wang, Jianjian Nature Chemistry, Vol. 11, Issue 7 https://doi.org/10.1038/s41557-019-0263-4	journal	May 2019
Site-selective CO disproportionation mediated by localized surface plasmon resonance excited by electron beam Yang, Wei-Chang D.; Wang, Canhui; Fredin, Lisa A. Nature Materials, Vol. 18, Issue 6 https://doi.org/10.1038/s41563-019-0342-3	journal	April 2019
Structural evolution of atomically dispersed Pt catalysts dictates reactivity DeRita, Leo; Resasco, Joaquin; Dai, Sheng Nature Materials, Vol. 18, Issue 7 https://doi.org/10.1038/s41563-019-0349-9	journal	April 2019
Towards data-driven next-generation transmission electron microscopy Spurgeon, Steven R.; Ophus, Colin; Jones, Lewys Nature Materials https://doi.org/10.1038/s41563-020-00833-z	journal	October 2020
2D metal–organic framework for stable perovskite solar cells with minimized lead leakage Wu, Shengfan; Li, Zhen; Li, Mu-Qing Nature Nanotechnology, Vol. 15, Issue 11 https://doi.org/10.1038/s41565-020-0765-7	journal	September 2020
Vibrational spectroscopy at atomic resolution with electron impact scattering Venkatraman, Kartik; Levin, Barnaby D. A.; March, Katia Nature Physics, Vol. 15, Issue 12 https://doi.org/10.1038/s41567-019-0675-5	journal	October 2019
Cryo-STEM mapping of solid–liquid interfaces and dendrites in lithium-metal batteries Zachman, Michael J.; Tu, Zhengyuan; Choudhury, Snehashis Nature, Vol. 560, Issue 7718 https://doi.org/10.1038/s41586-018-0397-3	journal	August 2018
Visualizing vibrational normal modes of a single molecule with atomically confined light Lee, Joonhee; Crampton, Kevin T.; Tallarida, Nicholas Nature, Vol. 568, Issue 7750 https://doi.org/10.1038/s41586-019-1059-9	journal	April 2019
Position and momentum mapping of vibrations in graphene nanostructures Senga, Ryosuke; Suenaga, Kazu; Barone, Paolo Nature, Vol. 573, Issue 7773 https://doi.org/10.1038/s41586-019-1477-8	journal	August 2019
Single-defect phonons imaged by electron microscopy Yan, Xingxu; Liu, Chengyan; Gadre, Chaitanya A. Nature, Vol. 589, Issue 7840 https://doi.org/10.1038/s41586-020-03049-y	journal	January 2021
Exploring the capabilities of monochromated electron energy loss spectroscopy in the infrared regime Hachtel, Jordan A.; Lupini, Andrew R.; Idrobo, Juan Carlos Scientific Reports, Vol. 8, Issue 1 https://doi.org/10.1038/s41598-018-23805-5	journal	April 2018
Quantifying transmission electron microscopy irradiation effects using two-dimensional materials Susi, Toma; Meyer, Jannik C.; Kotakoski, Jani Nature Reviews Physics, Vol. 1, Issue 6 https://doi.org/10.1038/s42254-019-0058-y	journal	May 2019
Misfolded proteins in Alzheimer's disease and type II diabetes DeToma, Alaina S.; Salamekh, Samer; Ramamoorthy, Ayyalusamy Chem. Soc. Rev., Vol. 41, Issue 2 https://doi.org/10.1039/C1CS15112F	journal	January 2012
How many water molecules are needed to solvate one? Rognoni, Alessandro; Conte, Riccardo; Ceotto, Michele Chemical Science, Vol. 12, Issue 6 https://doi.org/10.1039/D0SC05785A	journal	January 2021
Development of a high energy resolution electron energy-loss spectroscopy microscope: HIGH ENERGY RESOLUTION EELS MICROSCOPE No authors listed Journal of Microscopy, Vol. 194, Issue 1 https://doi.org/10.1046/j.1365-2818.1999.00450.x	journal	April 1999
Performance of a new high-resolution electron energy-loss spectroscopy microscope Thrauchi, Masami; Kuzuo, Ryuichi; Satoh, Futami Microscopy Microanalysis Microstructures, Vol. 2, Issue 2-3 https://doi.org/10.1051/mmm:0199100202-3035100	journal	January 1991
Staining of Tissue Sections for Electron Microscopy with Heavy Metals Watson, Michael L. The Journal of Biophysical and Biochemical Cytology, Vol. 4, Issue 4 https://doi.org/10.1083/jcb.4.4.475	journal	July 1958
Phonon spectroscopy by inelastic x-ray scattering Burkel, Eberhard Reports on Progress in Physics, Vol. 63, Issue 2 https://doi.org/10.1088/0034-4885/63/2/203	journal	January 2000
Monochromated STEM with a 30 meV-wide, atom-sized electron probe Krivanek, Ondrej L.; Lovejoy, Tracy C.; Dellby, Niklas Microscopy, Vol. 62, Issue 1 https://doi.org/10.1093/jmicro/dfs089	journal	January 2013
Measurement of vibrational spectrum of liquid using monochromated scanning transmission electron microscopy–electron energy loss spectroscopy Miyata, Tomohiro; Fukuyama, Mao; Hibara, Akihide Microscopy, Vol. 63, Issue 5 https://doi.org/10.1093/jmicro/dfu023	journal	July 2014
Practical aspects of monochromators developed for transmission electron microscopy Kimoto, Koji Microscopy, Vol. 63, Issue 5 https://doi.org/10.1093/jmicro/dfu027	journal	August 2014
Quantum mechanical model for phonon excitation in electron diffraction and imaging using a Born-Oppenheimer approximation Forbes, B. D.; Martin, A. V.; Findlay, S. D. Physical Review B, Vol. 82, Issue 10 https://doi.org/10.1103/PhysRevB.82.104103	journal	September 2010
Localization of high-energy electron scattering from atomic vibrations Dwyer, C. Physical Review B, Vol. 89, Issue 5 https://doi.org/10.1103/PhysRevB.89.054103	journal	February 2014
Prospects of spatial resolution in vibrational electron energy loss spectroscopy: Implications of dipolar scattering Dwyer, Christian Physical Review B, Vol. 96, Issue 22 https://doi.org/10.1103/PhysRevB.96.224102	journal	December 2017
Inelastic vibrational bulk and surface losses of swift electrons in ionic nanostructures Hohenester, Ulrich; Trügler, Andreas; Batson, Philip E. Physical Review B, Vol. 97, Issue 16 https://doi.org/10.1103/PhysRevB.97.165418	journal	April 2018
Vibrational electron energy loss spectroscopy in truncated dielectric slabs Konečná, Andrea; Venkatraman, Kartik; March, Katia Physical Review B, Vol. 98, Issue 20 https://doi.org/10.1103/PhysRevB.98.205409	journal	November 2018
Theory of momentum-resolved phonon spectroscopy in the electron microscope Nicholls, R. J.; Hage, F. S.; McCulloch, D. G. Physical Review B, Vol. 99, Issue 9 https://doi.org/10.1103/PhysRevB.99.094105	journal	March 2019
Atomic-Resolution Imaging with a Sub-50-pm Electron Probe Erni, Rolf; Rossell, Marta D.; Kisielowski, Christian Physical Review Letters, Vol. 102, Issue 9 https://doi.org/10.1103/PhysRevLett.102.096101	journal	March 2009
Chromatic Aberration Correction for Atomic Resolution TEM Imaging from 20 to 80 kV Linck, Martin; Hartel, Peter; Uhlemann, Stephan Physical Review Letters, Vol. 117, Issue 7 https://doi.org/10.1103/PhysRevLett.117.076101	journal	August 2016
Electron-Beam Mapping of Vibrational Modes with Nanometer Spatial Resolution Dwyer, C.; Aoki, T.; Rez, P. Physical Review Letters, Vol. 117, Issue 25 https://doi.org/10.1103/PhysRevLett.117.256101	journal	December 2016
First-Principles Vibrational Electron Energy Loss Spectroscopy of β -Guanine Radtke, G.; Taverna, D.; Lazzeri, M. Physical Review Letters, Vol. 119, Issue 2 https://doi.org/10.1103/PhysRevLett.119.027402	journal	July 2017
Phonon Spectroscopy at Atomic Resolution Hage, F. S.; Kepaptsoglou, D. M.; Ramasse, Q. M. Physical Review Letters, Vol. 122, Issue 1 https://doi.org/10.1103/PhysRevLett.122.016103	journal	January 2019
Polarization Selectivity in Vibrational Electron-Energy-Loss Spectroscopy Radtke, G.; Taverna, D.; Menguy, N. Physical Review Letters, Vol. 123, Issue 25 https://doi.org/10.1103/PhysRevLett.123.256001	journal	December 2019
Low-Energy Magnetic Excitations of the Mn 12 -Acetate Spin Cluster Observed by Neutron Scattering Mirebeau, I.; Hennion, M.; Casalta, H. Physical Review Letters, Vol. 83, Issue 3 https://doi.org/10.1103/PhysRevLett.83.628	journal	July 1999
Optical excitations in electron microscopy García de Abajo, F. J. Reviews of Modern Physics, Vol. 82, Issue 1 https://doi.org/10.1103/RevModPhys.82.209	journal	February 2010
Protein secondary structure signatures from energy loss spectra recorded in the electron microscope March, Katia; Venkatraman, Kartik; Truong, Chloe Du Journal of Microscopy, Vol. 282, Issue 3 https://doi.org/10.1111/jmi.12995	journal	January 2021
Isotopic compositions, nitrogen functional chemistry, and low‐loss electron spectroscopy of complex organic aggregates at the nanometer scale in the carbonaceous chondrite Renazzo Vollmer, Christian; Leitner, Jan; Kepaptsoglou, Demie Meteoritics & Planetary Science, Vol. 55, Issue 6 https://doi.org/10.1111/maps.13389	journal	October 2019
Nanoscale momentum-resolved vibrational spectroscopy Hage, Fredrik S.; Nicholls, Rebecca J.; Yates, Jonathan R. Science Advances, Vol. 4, Issue 6 https://doi.org/10.1126/sciadv.aar7495	journal	June 2018
Capturing 3D atomic defects and phonon localization at the 2D heterostructure interface Tian, Xuezeng; Yan, Xingxu; Varnavides, Georgios Science Advances, Vol. 7, Issue 38 https://doi.org/10.1126/sciadv.abi6699	journal	September 2021
Visualizing Gas Molecules Interacting with Supported Nanoparticulate Catalysts at Reaction Conditions Yoshida, H.; Kuwauchi, Y.; Jinschek, J. R. Science, Vol. 335, Issue 6066 https://doi.org/10.1126/science.1213194	journal	January 2012
Single-Molecule Vibrational Spectroscopy and Microscopy Stipe, B. C. Science, Vol. 280, Issue 5370 https://doi.org/10.1126/science.280.5370.1732	journal	June 1998
Opportunities and challenges in liquid cell electron microscopy Ross, F. M. Science, Vol. 350, Issue 6267 https://doi.org/10.1126/science.aaa9886	journal	December 2015
Single-particle mapping of nonequilibrium nanocrystal transformations Ye, Xingchen; Jones, Matthew R.; Frechette, Layne B. Science, Vol. 354, Issue 6314 https://doi.org/10.1126/science.aah4434	journal	November 2016
Atomic-resolution transmission electron microscopy of electron beam–sensitive crystalline materials Zhang, Daliang; Zhu, Yihan; Liu, Lingmei Science, Vol. 359, Issue 6376 https://doi.org/10.1126/science.aao0865	journal	January 2018
Fibril structure of amyloid-β(1–42) by cryo–electron microscopy Gremer, Lothar; Schölzel, Daniel; Schenk, Carla Science, Vol. 358, Issue 6359 https://doi.org/10.1126/science.aao2825	journal	September 2017
Identification of site-specific isotopic labels by vibrational spectroscopy in the electron microscope Hachtel, Jordan A.; Huang, Jingsong; Popovs, Ilja Science, Vol. 363, Issue 6426 https://doi.org/10.1126/science.aav5845	journal	January 2019
Probing and imaging spin interactions with a magnetic single-molecule sensor Czap, Gregory; Wagner, Peter J.; Xue, Feng Science, Vol. 364, Issue 6441 https://doi.org/10.1126/science.aaw7505	journal	May 2019
Critical differences in 3D atomic structure of individual ligand-protected nanocrystals in solution Kim, Byung Hyo; Heo, Junyoung; Kim, Sungin Science, Vol. 368, Issue 6486 https://doi.org/10.1126/science.aax3233	journal	April 2020
Single-atom vibrational spectroscopy in the scanning transmission electron microscope Hage, F. S.; Radtke, G.; Kepaptsoglou, D. M. Science, Vol. 367, Issue 6482 https://doi.org/10.1126/science.aba1136	journal	March 2020
Atomic-scale microstructure of metal halide perovskite Rothmann, Mathias Uller; Kim, Judy S.; Borchert, Juliane Science, Vol. 370, Issue 6516 https://doi.org/10.1126/science.abb5940	journal	October 2020
New Opportunities in Micro- and Macro-Attenuated Total Reflection Infrared Spectroscopic Imaging: Spatial Resolution and Sampling Versatility Chan, K. L. A.; Kazarian, S. G. Applied Spectroscopy, Vol. 57, Issue 4 https://doi.org/10.1366/00037020360625907	journal	April 2003
Probing structural changes in single enveloped virus particles using nano-infrared spectroscopic imaging Gamage, Sampath; Howard, Marquez; Makita, Hiroki PLOS ONE, Vol. 13, Issue 6 https://doi.org/10.1371/journal.pone.0199112	journal	June 2018
Development of electron energy-loss spectroscopy in the biological sciences Aronova, M. A.; Leapman, R. D. MRS Bulletin, Vol. 37, Issue 1 https://doi.org/10.1557/mrs.2011.329	journal	January 2012
Nucleation, growth, and superlattice formation of nanocrystals observed in liquid cell transmission electron microscopy Chen, Qian; Yuk, Jong Min; Hauwiller, Matthew R. MRS Bulletin, Vol. 45, Issue 9 https://doi.org/10.1557/mrs.2020.229	journal	September 2020
Chemical and bonding analysis of liquids using liquid cell electron microscopy Ercius, Peter; Hachtel, Jordan A.; Klie, Robert F. MRS Bulletin, Vol. 45, Issue 9 https://doi.org/10.1557/mrs.2020.230	journal	September 2020
In Situ TEM Studies of Catalysts Using Windowed Gas Cells Ye, Fan; Xu, Mingjie; Dai, Sheng Catalysts, Vol. 10, Issue 7 https://doi.org/10.3390/catal10070779	journal	July 2020

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Vibrational Spectroscopy
37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY
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Probing molecular vibrations by monochromated electron microscopy

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