The efficient delivery of reactive and toxic gaseous reagents to organic reactions was studied using metal-organic frameworks (MOFs). The simultaneous cargo vehicle and catalytic capabilities of several MOFs were probed for the first time using the examples of aromatization, aminocarbonylation, and carbonylative Suzuki–Miyaura coupling reactions. These reactions highlight that MOFs can serve a dual role as a gas cargo vehicle and a catalyst, leading to product formation with yields similar to reactions employing pure gases. Furthermore, the MOFs can be recycled without sacrificing product yield, while simultaneously maintaining crystallinity. Our reported findings were supported crystallographically and spectroscopically (e.g., diffuse reflectance infrared Fourier transform spectroscopy), foreshadowing a pathway for the development of multifunctional MOF-based reagent-catalyst cargo vessels for reactive gas reagents as an attractive alternative to the use of toxic pure gases or gas generators.
Kittikhunnatham, Preecha, Leith, Gabrielle A., Mathur, Abhijai, Naglic, Jennifer K., Martin, Corey R., Park, Kyoung Chul, McCullough, Katherine, Jayaweera, H. Chathumal, Corkill, Ryan E., Lauterbach, Jochen, Karakalos, Stavros G., Smith, Mark D., Garashchuk, Sophya, Chen, Donna A., & Shustova, Natalia B. (2021). A Metal-Organic Framework (MOF)-Based Multifunctional Cargo Vehicle for Reactive-Gas Delivery and Catalysis. Angewandte Chemie (International Edition), 61(12). https://doi.org/10.1002/anie.202113909
Kittikhunnatham, Preecha, Leith, Gabrielle A., Mathur, Abhijai, et al., "A Metal-Organic Framework (MOF)-Based Multifunctional Cargo Vehicle for Reactive-Gas Delivery and Catalysis," Angewandte Chemie (International Edition) 61, no. 12 (2021), https://doi.org/10.1002/anie.202113909
@article{osti_1976272,
author = {Kittikhunnatham, Preecha and Leith, Gabrielle A. and Mathur, Abhijai and Naglic, Jennifer K. and Martin, Corey R. and Park, Kyoung Chul and McCullough, Katherine and Jayaweera, H. Chathumal and Corkill, Ryan E. and Lauterbach, Jochen and others},
title = {A Metal-Organic Framework (MOF)-Based Multifunctional Cargo Vehicle for Reactive-Gas Delivery and Catalysis},
annote = {The efficient delivery of reactive and toxic gaseous reagents to organic reactions was studied using metal-organic frameworks (MOFs). The simultaneous cargo vehicle and catalytic capabilities of several MOFs were probed for the first time using the examples of aromatization, aminocarbonylation, and carbonylative Suzuki–Miyaura coupling reactions. These reactions highlight that MOFs can serve a dual role as a gas cargo vehicle and a catalyst, leading to product formation with yields similar to reactions employing pure gases. Furthermore, the MOFs can be recycled without sacrificing product yield, while simultaneously maintaining crystallinity. Our reported findings were supported crystallographically and spectroscopically (e.g., diffuse reflectance infrared Fourier transform spectroscopy), foreshadowing a pathway for the development of multifunctional MOF-based reagent-catalyst cargo vessels for reactive gas reagents as an attractive alternative to the use of toxic pure gases or gas generators.},
doi = {10.1002/anie.202113909},
url = {https://www.osti.gov/biblio/1976272},
journal = {Angewandte Chemie (International Edition)},
issn = {ISSN 1433-7851},
number = {12},
volume = {61},
place = {United States},
publisher = {Wiley},
year = {2021},
month = {11}}
University of South Carolina, Columbia, SC (United States)
Sponsoring Organization:
USDOE Office of Science (SC), Basic Energy Sciences (BES); Dreyfus Foundation; Hans Fischer fellowship; National Science Foundation (NSF); University of South Carolina
Grant/Contract Number:
SC0019360
OSTI ID:
1976272
Journal Information:
Angewandte Chemie (International Edition), Journal Name: Angewandte Chemie (International Edition) Journal Issue: 12 Vol. 61; ISSN 1433-7851
