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Title: Transformation Efficiency of RasQ61 Mutants Linked to Structural Features of the Switch Regions in the Presence of Raf

Journal Article · · Structure
; ;

Sponsoring Organization:
USDOE Office of Science (SC), Basic Energy Sciences (BES)
Grant/Contract Number:
W-31-109-Eng-38
OSTI ID:
1926726
Journal Information:
Structure, Journal Name: Structure Vol. 15 Journal Issue: 12; ISSN 0969-2126
Publisher:
ElsevierCopyright Statement
Country of Publication:
United Kingdom
Language:
English

References (37)

Vibrational Structure of GDP and GTP Bound to RAS:  An Isotope-Edited FTIR Study journal March 2001
Quantitative Analysis of the Complex between p21 and the Ras-binding Domain of the Human Raf-1 Protein Kinase journal February 1995
Role of Glutamine-61 in the Hydrolysis of GTP by p21H-ras: An Experimental and Theoretical Study journal March 1994
ras Genes journal June 1987
Regional Polysterism in the GTP-Bound Form of the Human c-Ha-Ras Protein † , ‡ journal July 1997
Disassembly of RanGTP-Karyopherin β Complex, an Intermediate in Nuclear Protein Import journal August 1997
Conformational Transitions in p21 ras and in Its Complexes with the Effector Protein Raf-RBD and the GTPase Activating Protein GAP † journal January 1996
Guanosine triphosphatase activating protein (GAP) interacts with the p21 ras effector binding domain journal April 1988
Coot model-building tools for molecular graphics journal November 2004
Increasing complexity of Ras signaling journal September 1998
Checking your imagination: applications of the free R value journal August 1996
G PROTEIN MECHANISMS:Insights from Structural Analysis journal June 1997
Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination journal September 1998
Ras-catalyzed hydrolysis of GTP: a new perspective from model studies. journal August 1996
The pre-hydrolysis state of p21ras in complex with GTP: new insights into the role of water molecules in the GTP hydrolysis reaction of ras-like proteins journal November 1999
Observation of Slow Dynamic Exchange Processes in Ras Protein Crystals by 31P Solid State NMR Spectroscopy journal November 2002
Structural View of the Ran–Importin β Interaction at 2.3 Å Resolution journal May 1999
Structure of a Transient Intermediate for GTP Hydrolysis by Ras journal March 2006
The 2.2 Å crystal structure of the Ras-binding domain of the serine/threonine kinase c-Raf1 in complex with RaplA and a GTP analogue journal June 1995
Improved methods for building protein models in electron density maps and the location of errors in these models journal March 1991
Three-dimensional structures of H-ras p21 mutants: Molecular basis for their inability to function as signal switch molecules journal August 1990
Biological and biochemical properties of human rasH genes mutated at codon 61 journal January 1986
The interpretation of protein structures: Estimation of static accessibility journal February 1971
NMR Characterization of Full-length Farnesylated and Non-farnesylated H-Ras and its Implications for Raf Activation journal November 2004
Organic Solvents Order the Dynamic Switch II in Ras Crystals journal July 2003
β-turns in proteins journal September 1977
Substrate assisted catalysis – application to G proteins journal March 2001
The Ras-RasGAP Complex: Structural Basis for GTPase Activation and Its Loss in Oncogenic Ras Mutants journal July 1997
The structural basis for the transition from Ras-GTP to Ras-GDP journal September 2002
Distributions of water around amino acid residues in proteins journal August 1988
GTP Hydrolysis Mechanism of Ras-like GTPases journal July 2004
The Hallmarks of Cancer journal January 2000
[20] Processing of X-ray diffraction data collected in oscillation mode book January 1997
Ras/Rap effector specificity determined by charge reversal journal August 1996
Crystallographic Evidence for Substrate-Assisted GTP Hydrolysis by a Small GTP Binding Protein journal April 2005
Comparing the polarities of the amino acids: side-chain distribution coefficients between the vapor phase, cyclohexane, 1-octanol, and neutral aqueous solution journal March 1988
A Novel Class of RanGTP Binding Proteins journal July 1997

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