Whole genome resequencing data from a collection of Clostridium Thermocellum strains
- Dartmouth College, Hanover, NH (United States)
- National Renewable Energy Lab. (NREL), Golden, CO (United States)
- Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)
Clostridium thermocellum is an anaerobic thermophilic bacterium that natively ferments cellulose to ethanol and organic acids. This data set is a collection of whole genome resequencing data for several hundred strains of Clostridium thermocellum. It includes strains that have been engineered to increase ethanol production, strains that have been engineered to understand microbial physiology, and strains that have been adapted for desired phenotypes including increased ethanol tolerance. Resequencing data consists of paired Illumina reads, 100-150 bp on each end, with a ~500 bp insert size. One data file containing raw Illumina data (interleaved) is available for each strain. We also provide data describing the mutations identified in each strain, and distinguish between inherited and newly observed mutations. In addition to resequencing data, we also provide metadata describing the lineage of each strain, and any targeted genetic modifications.
- Research Organization:
- Oak Ridge National Laboratory (ORNL), Oak Ridge, TN (United States)
- Sponsoring Organization:
- USDOE Office of Science (SC), Biological and Environmental Research (BER)
- DOE Contract Number:
- AC05-00OR22725
- OSTI ID:
- 1923916
- Country of Publication:
- United States
- Language:
- English
Similar Records
Metabolic and evolutionary responses of Clostridium thermocellum to genetic interventions aimed at improving ethanol production
A Single Nucleotide Change in the polC DNA Polymerase III in Clostridium thermocellum Is Sufficient To Create a Hypermutator Phenotype