Conservation of Dynamics Associated with Biological Function in an Enzyme Superfamily
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March 2018 |
Protein Tyrosine Phosphatases in the Human Genome
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June 2004 |
Quantitative measurement of exchange dynamics in proteins via 13C relaxation dispersion of 13CHD2-labeled samples
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June 2016 |
Ligand-dependent Dynamics and Intramolecular Signaling in a PDZ Domain
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January 2004 |
Enzymes at work are enzymes in motion
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January 2017 |
The Michaelis Complex of Arginine Kinase Samples the Transition State at a Frequency That Matches the Catalytic Rate
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March 2017 |
Patterns of coevolving amino acids unveil structural and dynamical domains
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November 2017 |
Structural Basis for Inhibition of the Protein Tyrosine Phosphatase 1B by Phosphotyrosine Peptide Mimetics ,
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December 1998 |
Conservation of Side-Chain Dynamics Within a Protein Family
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April 2009 |
Structural and Evolutionary Relationships among Protein Tyrosine Phosphatase Domains
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November 2001 |
Structure-based Design of a Low Molecular Weight, Nonphosphorus, Nonpeptide, and Highly Selective Inhibitor of Protein-tyrosine Phosphatase 1B
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April 2000 |
The challenge of predicting distal active site mutations in computational enzyme design
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August 2020 |
Defining the Structural Basis for Allosteric Product Release from E. coli Dihydrofolate Reductase Using NMR Relaxation Dispersion
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July 2017 |
Improved contact prediction in proteins: Using pseudolikelihoods to infer Potts models
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January 2013 |
Intrinsic dynamics of an enzyme underlies catalysis
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November 2005 |
Choreographing an enzyme's dance
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October 2010 |
Molecular Basis for the Dephosphorylation of the Activation Segment of the Insulin Receptor by Protein Tyrosine Phosphatase 1B
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December 2000 |
Cooperative dynamics across distinct structural elements regulate PTP1B activity
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October 2020 |
Uncovering the Molecular Interactions in the Catalytic Loop That Modulate the Conformational Dynamics in Protein Tyrosine Phosphatase 1B
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July 2019 |
UniRef clusters: a comprehensive and scalable alternative for improving sequence similarity searches
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November 2014 |
A Dynamic Knockout Reveals That Conformational Fluctuations Influence the Chemical Step of Enzyme Catalysis
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April 2011 |
Crystal structure of human protein tyrosine phosphatase 1B
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March 1994 |
Loop Dynamics and Enzyme Catalysis in Protein Tyrosine Phosphatases
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March 2021 |
Hinge-shift mechanism as a protein design principle for the evolution of β-lactamases from substrate promiscuity to specificity
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March 2021 |
Conformational dynamics and enzyme evolution
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July 2018 |
Principles that Govern the Folding of Protein Chains
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July 1973 |
Linkage between dynamics and catalysis in a thermophilic-mesophilic enzyme pair
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August 2004 |
The Dynamic Energy Landscape of Dihydrofolate Reductase Catalysis
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September 2006 |
Purification of the major protein-tyrosine-phosphatases of human placenta.
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May 1988 |
Quantitative 13C and 2H NMR Relaxation Studies of the 723-Residue Enzyme Malate Synthase G Reveal a Dynamic Binding Interface
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November 2005 |
NMR spectroscopy captures the essential role of dynamics in regulating biomolecular function
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February 2021 |
NMR View: A computer program for the visualization and analysis of NMR data
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September 1994 |
Conformational Rigidity and Protein Dynamics at Distinct Timescales Regulate PTP1B Activity and Allostery
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February 2017 |
Crystal Structure of TCPTP Unravels an Allosteric Regulatory Role of Helix α7 in Phosphatase Activity
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December 2021 |
Visualization of the Cysteinyl-phosphate Intermediate of a Protein-tyrosine Phosphatase by X-ray Crystallography
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April 1998 |
The catalytic activity of TCPTP is auto-regulated by its intrinsically disordered tail and activated by Integrin alpha-1
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January 2022 |
NMR detection of multiple transitions to low-populated states in azurin
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January 2003 |
Protein Tyrosine Phosphatases in Hypothalamic Insulin and Leptin Signaling
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October 2015 |
Structural Basis of Plasticity in Protein Tyrosine Phosphatase 1B Substrate Recognition † , ‡
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July 2000 |
HMMER web server: 2015 update
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May 2015 |
An expanded allosteric network in PTP1B by multitemperature crystallography, fragment screening, and covalent tethering
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June 2018 |
Correlation between 2H NMR Side-Chain Order Parameters and Sequence Conservation in Globular Proteins
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July 2003 |
Allosteric inhibition of protein tyrosine phosphatase 1B
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July 2004 |
Optogenetic Analysis of Allosteric Control in Protein Tyrosine Phosphatases
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January 2021 |
The CCPN data model for NMR spectroscopy: Development of a software pipeline
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April 2005 |
Retinoic Acid Binding Leads to CRABP2 Rigidification and Dimerization
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September 2019 |
Conformational Motions Regulate Phosphoryl Transfer in Related Protein Tyrosine Phosphatases
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August 2013 |
Dynamic activation and regulation of the mitogen-activated protein kinase p38
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April 2018 |
Rational design of allosteric-inhibition sites in classical protein tyrosine phosphatases
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June 2015 |
A global analysis of function and conservation of catalytic residues in enzymes
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January 2020 |