Structural and functional insights into transmembrane AMPA receptor regulatory protein complexes

Twomey, Edward C.; Yelshanskaya, Maria V.; Sobolevsky, Alexander I.

doi:10.1085/jgp.201812264

Structural and functional insights into transmembrane AMPA receptor regulatory protein complexes

Journal Article · Tue Oct 01 00:00:00 EDT 2019 · J. Gen. Physiol.

DOI:https://doi.org/10.1085/jgp.201812264· OSTI ID:1900759

Twomey, Edward C.; Yelshanskaya, Maria V.; Sobolevsky, Alexander I.

Research Organization:: Advanced Photon Source (APS), Argonne National Laboratory (ANL), Argonne, IL (US)

Sponsoring Organization:: DOE - Office Of Science; NIH

OSTI ID:: 1900759

Journal Information:: J. Gen. Physiol., Journal Name: J. Gen. Physiol. Journal Issue: (12) Vol. 151

Country of Publication:: United States

Language:: ENGLISH

References (65)

X-ray structure, symmetry and mechanism of an AMPA-subtype glutamate receptor Sobolevsky, Alexander I.; Rosconi, Michael P.; Gouaux, Eric Nature, Vol. 462, Issue 7274 https://doi.org/10.1038/nature08624	journal	November 2009
Channel opening and gating mechanism in AMPA-subtype glutamate receptors Twomey, Edward C.; Yelshanskaya, Maria V.; Grassucci, Robert A. Nature, Vol. 549, Issue 7670 https://doi.org/10.1038/nature23479	journal	July 2017
Architecture of fully occupied GluA2 AMPA receptor–TARP complex elucidated by cryo-EM Zhao, Yan; Chen, Shanshuang; Yoshioka, Craig Nature, Vol. 536, Issue 7614 https://doi.org/10.1038/nature18961	journal	July 2016
Forebrain-selective AMPA-receptor antagonism guided by TARP γ-8 as an antiepileptic mechanism Kato, Akihiko S.; Burris, Kevin D.; Gardinier, Kevin M. Nature Medicine, Vol. 22, Issue 12 https://doi.org/10.1038/nm.4221	journal	November 2016
Stargazin Modulation of AMPA Receptors Shaikh, Sana A.; Dolino, Drew M.; Lee, Garam Cell Reports, Vol. 17, Issue 2 https://doi.org/10.1016/j.celrep.2016.09.014	journal	October 2016
Structural biology of glutamate receptor ion channel complexes Mayer, Mark L. Current Opinion in Structural Biology, Vol. 41 https://doi.org/10.1016/j.sbi.2016.07.002	journal	December 2016
Differences in AMPA and Kainate Receptor Interactomes Facilitate Identification of AMPA Receptor Auxiliary Subunit GSG1L Shanks, Natalie F.; Savas, Jeffrey N.; Maruo, Tomohiko Cell Reports, Vol. 1, Issue 6 https://doi.org/10.1016/j.celrep.2012.05.004	journal	June 2012
Structural Bases of Desensitization in AMPA Receptor-Auxiliary Subunit Complexes Twomey, Edward C.; Yelshanskaya, Maria V.; Grassucci, Robert A. Neuron, Vol. 94, Issue 3 https://doi.org/10.1016/j.neuron.2017.04.025	journal	May 2017
The Relationship between Agonist Potency and AMPA Receptor Kinetics Zhang, Wei; Robert, Antoine; Vogensen, Stine B. Biophysical Journal, Vol. 91, Issue 4 https://doi.org/10.1529/biophysj.106.084426	journal	August 2006
Hippocampal neurons exhibit cyclothiazide-sensitive rapidly desensitizing responses to kainate Patneau, Dk; Vyklicky, L.; Mayer, Ml The Journal of Neuroscience, Vol. 13, Issue 8 https://doi.org/10.1523/JNEUROSCI.13-08-03496.1993	journal	August 1993
Electrophysiological Properties of AMPA Receptors Are Differentially Modulated Depending on the Associated Member of the TARP Family Kott, S.; Werner, M.; Korber, C. Journal of Neuroscience, Vol. 27, Issue 14 https://doi.org/10.1523/JNEUROSCI.4185-06.2007	journal	April 2007
Control of Kinetic Properties of AMPA Receptor Channels by Nuclear RNA Editing Lomeli, Hilda; Mosbacher, Johannes; Melcher, Thorsten Science, Vol. 266, Issue 5191 https://doi.org/10.1126/science.7992055	journal	December 1994
AMPA Receptor Flip/Flop Mutants Affecting Deactivation, Desensitization, and Modulation by Cyclothiazide, Aniracetam, and Thiocyanate Partin, Kathryn M.; Fleck, Mark W.; Mayer, Mark L. The Journal of Neuroscience, Vol. 16, Issue 21 https://doi.org/10.1523/JNEUROSCI.16-21-06634.1996	journal	November 1996
Ion permeation in ionotropic glutamate receptors: still dynamic after all these years Wollmuth, Lonnie P. Current Opinion in Physiology, Vol. 2 https://doi.org/10.1016/j.cophys.2017.12.003	journal	April 2018
Flip and flop: a cell-specific functional switch in glutamate-operated channels of the CNS Sommer, B.; Keinanen, K.; Verdoorn, T. Science, Vol. 249, Issue 4976 https://doi.org/10.1126/science.1699275	journal	September 1990
Functional Insights from Glutamate Receptor Ion Channel Structures Kumar, Janesh; Mayer, Mark L. Annual Review of Physiology, Vol. 75, Issue 1 https://doi.org/10.1146/annurev-physiol-030212-183711	journal	February 2013
Auxiliary subunits keep AMPA receptors compact during activation and desensitization Baranovic, Jelena; Plested, Andrew JR eLife, Vol. 7 https://doi.org/10.7554/eLife.40548	journal	December 2018
Stargazin controls the pharmacology of AMPA receptor potentiators Tomita, Susumu; Sekiguchi, Masayuki; Wada, Keiji Proceedings of the National Academy of Sciences, Vol. 103, Issue 26 https://doi.org/10.1073/pnas.0603128103	journal	June 2006
Nanoscale Mobility of the Apo State and TARP Stoichiometry Dictate the Gating Behavior of Alternatively Spliced AMPA Receptors Dawe, G. Brent; Kadir, Md. Fahim; Venskutonytė, Raminta Neuron, Vol. 102, Issue 5 https://doi.org/10.1016/j.neuron.2019.03.046	journal	June 2019
The Role of RNA Editing in Controlling Glutamate Receptor Channel Properties Seeburg, Peter H. Journal of Neurochemistry, Vol. 66, Issue 1 https://doi.org/10.1046/j.1471-4159.1996.66010001.x	journal	January 1996
The Stoichiometry of AMPA Receptors and TARPs Varies by Neuronal Cell Type Shi, Yun; Lu, Wei; Milstein, Aaron D. Neuron, Vol. 62, Issue 5 https://doi.org/10.1016/j.neuron.2009.05.016	journal	June 2009
Different Domains of the AMPA Receptor Direct Stargazin-mediated Trafficking and Stargazin-mediated Modulation of Kinetics Bedoukian, Matthew A.; Weeks, Autumn M.; Partin, Kathryn M. Journal of Biological Chemistry, Vol. 281, Issue 33 https://doi.org/10.1074/jbc.M600679200	journal	August 2006
Modulation of non-NMDA receptor gating by auxiliary subunits Howe, James R. The Journal of Physiology, Vol. 593, Issue 1 https://doi.org/10.1113/jphysiol.2014.273904	journal	September 2014
Cornichon-2 Modulates AMPA Receptor-Transmembrane AMPA Receptor Regulatory Protein Assembly to Dictate Gating and Pharmacology Gill, M. B.; Kato, A. S.; Roberts, M. F. Journal of Neuroscience, Vol. 31, Issue 18 https://doi.org/10.1523/JNEUROSCI.6271-10.2011	journal	May 2011
Stargazin modulates AMPA receptor gating and trafficking by distinct domains Tomita, Susumu; Adesnik, Hillel; Sekiguchi, Masayuki Nature, Vol. 435, Issue 7045 https://doi.org/10.1038/nature03624	journal	April 2005
Ionotropic Glutamate Receptors & CNS Disorders Bowie, Derek CNS & Neurological Disorders - Drug Targets, Vol. 7, Issue 2 https://doi.org/10.2174/187152708784083821	journal	April 2008
Superactivation of AMPA receptors by auxiliary proteins Carbone, Anna L.; Plested, Andrew J. R. Nature Communications, Vol. 7, Issue 1 https://doi.org/10.1038/ncomms10178	journal	January 2016
Structural Mechanisms of Gating in Ionotropic Glutamate Receptors Twomey, Edward C.; Sobolevsky, Alexander I. Biochemistry, Vol. 57, Issue 3 https://doi.org/10.1021/acs.biochem.7b00891	journal	October 2017
Glutamate Receptor Ion Channels: Structure, Regulation, and Function Traynelis, Stephen F.; Wollmuth, Lonnie P.; McBain, Chris J. Pharmacological Reviews, Vol. 62, Issue 3 https://doi.org/10.1124/pr.109.002451	journal	August 2010
Stargazin promotes closure of the AMPA receptor ligand-binding domain MacLean, David M.; Ramaswamy, Swarna S.; Du, Mei Journal of General Physiology, Vol. 144, Issue 6 https://doi.org/10.1085/jgp.201411287	journal	November 2014
Functional Proteomics Identify Cornichon Proteins as Auxiliary Subunits of AMPA Receptors Schwenk, J.; Harmel, N.; Zolles, G. Science, Vol. 323, Issue 5919 https://doi.org/10.1126/science.1167852	journal	March 2009
SynDIG1: An Activity-Regulated, AMPA- Receptor-Interacting Transmembrane Protein that Regulates Excitatory Synapse Development Kalashnikova, Evgenia; Lorca, Ramón A.; Kaur, Inderpreet Neuron, Vol. 65, Issue 1 https://doi.org/10.1016/j.neuron.2009.12.021	journal	January 2010
Glutamate Synapses in Human Cognitive Disorders Volk, Lenora; Chiu, Shu-Ling; Sharma, Kamal Annual Review of Neuroscience, Vol. 38, Issue 1 https://doi.org/10.1146/annurev-neuro-071714-033821	journal	July 2015
Synaptic AMPA receptor composition in development, plasticity and disease Henley, Jeremy M.; Wilkinson, Kevin A. Nature Reviews Neuroscience, Vol. 17, Issue 6 https://doi.org/10.1038/nrn.2016.37	journal	April 2016
Crystal Structure of a Claudin Provides Insight into the Architecture of Tight Junctions Suzuki, H.; Nishizawa, T.; Tani, K. Science, Vol. 344, Issue 6181 https://doi.org/10.1126/science.1248571	journal	April 2014
Porcupine Controls Hippocampal AMPAR Levels, Composition, and Synaptic Transmission Erlenhardt, Nadine; Yu, Hong; Abiraman, Kavitha Cell Reports, Vol. 14, Issue 4 https://doi.org/10.1016/j.celrep.2015.12.078	journal	February 2016
Calcium-permeable AMPA channels in neurodegenerative disease and ischemia Kwak, Shin; Weiss, John H. Current Opinion in Neurobiology, Vol. 16, Issue 3 https://doi.org/10.1016/j.conb.2006.05.004	journal	June 2006
Architecture of the heteromeric GluA1/2 AMPA receptor in complex with the auxiliary subunit TARP γ8 Herguedas, Beatriz; Watson, Jake F.; Ho, Hinze Science, Vol. 364, Issue 6438 https://doi.org/10.1126/science.aav9011	journal	March 2019
CKAMP44: A Brain-Specific Protein Attenuating Short-Term Synaptic Plasticity in the Dentate Gyrus von Engelhardt, Jakob; Mack, Volker; Sprengel, Rolf Science, Vol. 327, Issue 5972 https://doi.org/10.1126/science.1184178	journal	March 2010
Activation and Desensitization Mechanism of AMPA Receptor-TARP Complex by Cryo-EM Chen, Shanshuang; Zhao, Yan; Wang, Yuhang Cell, Vol. 170, Issue 6 https://doi.org/10.1016/j.cell.2017.07.045	journal	September 2017
Structure and gating of tetrameric glutamate receptors: Structure and gating of iGluRs Sobolevsky, Alexander I. The Journal of Physiology, Vol. 593, Issue 1 https://doi.org/10.1113/jphysiol.2013.264911	journal	November 2013
Control of AMPA receptor activity by the extracellular loops of auxiliary proteins Riva, Irene; Eibl, Clarissa; Volkmer, Rudolf eLife, Vol. 6 https://doi.org/10.7554/eLife.28680	journal	August 2017
AMPA receptor/TARP stoichiometry visualized by single-molecule subunit counting Hastie, Peter; Ulbrich, Maximilian H.; Wang, Hui-Li Proceedings of the National Academy of Sciences, Vol. 110, Issue 13 https://doi.org/10.1073/pnas.1218765110	journal	March 2013
Morphologic determinant of tight junctions revealed by claudin-3 structures Nakamura, Shun; Irie, Katsumasa; Tanaka, Hiroo Nature Communications, Vol. 10, Issue 1 https://doi.org/10.1038/s41467-019-08760-7	journal	February 2019
Structural insight into tight junction disassembly by Clostridium perfringens enterotoxin Saitoh, Yasunori; Suzuki, Hiroshi; Tani, Kazutoshi Science, Vol. 347, Issue 6223 https://doi.org/10.1126/science.1261833	journal	February 2015
Stargazin attenuates intracellular polyamine block of calcium-permeable AMPA receptors Soto, David; Coombs, Ian D.; Kelly, Leah Nature Neuroscience, Vol. 10, Issue 10 https://doi.org/10.1038/nn1966	journal	September 2007
Regulation of AMPA receptor gating and pharmacology by TARP auxiliary subunits Milstein, Aaron D.; Nicoll, Roger A. Trends in Pharmacological Sciences, Vol. 29, Issue 7 https://doi.org/10.1016/j.tips.2008.04.004	journal	July 2008
Structure and different conformational states of native AMPA receptor complexes Nakagawa, Terunaga; Cheng, Yifan; Ramm, Elizabeth Nature, Vol. 433, Issue 7025 https://doi.org/10.1038/nature03328	journal	February 2005
Molecular Mechanism of AMPA Receptor Modulation by TARP/Stargazin Ben-Yaacov, Anat; Gillor, Moshe; Haham, Tomer Neuron, Vol. 93, Issue 5 https://doi.org/10.1016/j.neuron.2017.01.032	journal	March 2017
Glutamate receptor pores Huettner, James E. The Journal of Physiology, Vol. 593, Issue 1 https://doi.org/10.1113/jphysiol.2014.272724	journal	May 2014
Stargazin Modulates Native AMPA Receptor Functional Properties by Two Distinct Mechanisms Turetsky, D. Journal of Neuroscience, Vol. 25, Issue 32 https://doi.org/10.1523/JNEUROSCI.1108-05.2005	journal	August 2005
AMPA-receptor specific biogenesis complexes control synaptic transmission and intellectual ability Brechet, Aline; Buchert, Rebecca; Schwenk, Jochen Nature Communications, Vol. 8, Issue 1 https://doi.org/10.1038/ncomms15910	journal	July 2017
Distinct Structural Pathways Coordinate the Activation of AMPA Receptor-Auxiliary Subunit Complexes Dawe, G. Brent; Musgaard, Maria; Aurousseau, Mark R. P. Neuron, Vol. 89, Issue 6 https://doi.org/10.1016/j.neuron.2016.01.038	journal	March 2016
Stargazin and cornichon-3 relieve polyamine block of AMPA receptors by enhancing blocker permeation Brown, Patricia M. G. E.; McGuire, Hugo; Bowie, Derek Journal of General Physiology, Vol. 150, Issue 1 https://doi.org/10.1085/jgp.201711895	journal	December 2017
Mechanisms of Channel Block in Calcium-Permeable AMPA Receptors Twomey, Edward C.; Yelshanskaya, Maria V.; Vassilevski, Alexander A. Neuron, Vol. 99, Issue 5 https://doi.org/10.1016/j.neuron.2018.07.027	journal	September 2018
The role of AMPA receptors in postsynaptic mechanisms of synaptic plasticity Chater, Thomas E.; Goda, Yukiko Frontiers in Cellular Neuroscience, Vol. 8 https://doi.org/10.3389/fncel.2014.00401	journal	November 2014
Stargazin regulates synaptic targeting of AMPA receptors by two distinct mechanisms Chen, Lu; Chetkovich, Dane M.; Petralia, Ronald S. Nature, Vol. 408, Issue 6815 https://doi.org/10.1038/35050030	journal	December 2000
Architecture and subunit arrangement of native AMPA receptors elucidated by cryo-EM Zhao, Yan; Chen, Shanshuang; Swensen, Adam C. Science, Vol. 364, Issue 6438 https://doi.org/10.1126/science.aaw8250	journal	April 2019
High-Resolution Proteomics Unravel Architecture and Molecular Diversity of Native AMPA Receptor Complexes Schwenk, Jochen; Harmel, Nadine; Brechet, Aline Neuron, Vol. 74, Issue 4 https://doi.org/10.1016/j.neuron.2012.03.034	journal	May 2012
Probing TARP Modulation of AMPA Receptor Conductance with Polyamine Toxins Jackson, A. C.; Milstein, A. D.; Soto, D. Journal of Neuroscience, Vol. 31, Issue 20 https://doi.org/10.1523/JNEUROSCI.6688-10.2011	journal	May 2011
Identification of a site in glutamate receptor subunits that controls calcium permeability Hume, R.; Dingledine, R.; Heinemann, S. Science, Vol. 253, Issue 5023 https://doi.org/10.1126/science.1653450	journal	August 1991
A novel action of stargazin as an enhancer of AMPA receptor activity Yamazaki, Maya; Ohno-Shosaku, Takako; Fukaya, Masahiro Neuroscience Research, Vol. 50, Issue 4 https://doi.org/10.1016/j.neures.2004.10.002	journal	December 2004
Assembly and Stoichiometry of the AMPA Receptor and Transmembrane AMPA Receptor Regulatory Protein Complex Kim, K. S.; Yan, D.; Tomita, S. Journal of Neuroscience, Vol. 30, Issue 3 https://doi.org/10.1523/JNEUROSCI.3909-09.2010	journal	January 2010
Elucidation of AMPA receptor–stargazin complexes by cryo–electron microscopy Twomey, Edward C.; Yelshanskaya, Maria V.; Grassucci, Robert A. Science, Vol. 353, Issue 6294 https://doi.org/10.1126/science.aaf8411	journal	June 2016
Stargazin Reduces Desensitization and Slows Deactivation of the AMPA-Type Glutamate Receptors Priel, A. Journal of Neuroscience, Vol. 25, Issue 10 https://doi.org/10.1523/JNEUROSCI.4834-04.2005	journal	March 2005

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