A toolkit for plant lipid engineering: surveying the efficacies of lipogenic factors for accumulating specialty lipids

Cai, Yingqi; Yu, Xiao-Hong; Shanklin, John

doi:10.3389/fpls.2022.1064176

Title: A toolkit for plant lipid engineering: surveying the efficacies of lipogenic factors for accumulating specialty lipids

Journal Article · Mon Nov 28 00:00:00 EST 2022 · Frontiers in Plant Science

DOI:https://doi.org/10.3389/fpls.2022.1064176· OSTI ID:1900388

Cai, Yingqi ^[1]; Yu, Xiao-Hong ^[2];

^[1]

Brookhaven National Laboratory (BNL), Upton, NY (United States)
Brookhaven National Laboratory (BNL), Upton, NY (United States); Stony Brook University, NY (United States)

Plants produce energy-dense lipids from carbohydrates using energy acquired via photosynthesis, making plant oils an economically and sustainably attractive feedstock for conversion to biofuels and value-added bioproducts. A growing number of strategies have been developed and optimized in model plants, oilseed crops and high-biomass crops to enhance the accumulation of storage lipids (mostly triacylglycerols, TAGs) for bioenergy applications and to produce specialty lipids with increased uses and value for chemical feedstock and nutritional applications. Most successful metabolic engineering strategies involve heterologous expression of lipogenic factors that outperform those from other sources or exhibit specialized functionality. In this review, we summarize recent progress in engineering the accumulation of triacylglycerols containing - specialized fatty acids in various plant species and tissues. We also provide an inventory of specific lipogenic factors derived from a wide variety of organisms, along with their reported efficacy in supporting the accumulation of desired lipids. A review of previously obtained results serves as a foundation to guide future efforts to optimize combinations of factors to achieve further enhancements to the production and accumulation of desired lipids in a variety of plant tissues and species.

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Research Organization:: Brookhaven National Lab. (BNL), Upton, NY (United States)

Sponsoring Organization:: USDOE Office of Science (SC), Biological and Environmental Research (BER)

Grant/Contract Number:: SC0012704

OSTI ID:: 1900388

Report Number(s):: BNL-223737-2022-JAAM

Journal Information:: Frontiers in Plant Science, Vol. 13; ISSN 1664-462X

Publisher:: Frontiers Research FoundationCopyright Statement

Country of Publication:: United States

Language:: English

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