System, emanation generator, and process for production of high-purity therapeutic radioisotopes

Patent · Tue May 31 00:00:00 EDT 2022

OSTI ID:1892995

O'Hara, Matthew J.

An isotope production system, emanation generator, and process are disclosed for production of high-purity radioisotopes. In one implementation example, high-purity Pb-212 and/or Bi-212 isotopes are produced suitable for therapeutic applications. In one embodiment the process includes transporting gaseous radon-220 from a radium-224 bearing generator which provides gas-phase separation of the Rn-220 from the Ra-224 in the generator. Subsequent decay of the captured Rn-220 accumulates high-purity Pb-212 and/or Bi-212 isotopes suitable for direct therapeutic applications. Other high-purity product isotopes may also be prepared.

• Research Organization: Pacific Northwest National Laboratory (PNNL), Richland, WA (United States)
• Sponsoring Organization: USDOE
• DOE Contract Number: AC05-76RL01830
• Assignee: Battelle Memorial Institute (Richland, WA)
• Patent Number(s): 11,348,702
• Application Number: 15/675,529
• OSTI ID: 1892995
• Country of Publication: United States
• Language: English