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Open port sampling interface

Patent ·
OSTI ID:1892871

A system for sampling a sample material includes a probe which can have an outer probe housing with an open end. A liquid supply conduit within the housing has an outlet positioned to deliver liquid to the open end of the housing. The liquid supply conduit can be connectable to a liquid supply for delivering liquid at a first volumetric flow rate to the open end of the housing. A liquid exhaust conduit within the housing is provided for removing liquid from the open end of the housing. A liquid exhaust system can be provided for removing liquid from the liquid exhaust conduit at a second volumetric flow rate. A droplet dispenser can dispense drops of a sample or a sample-containing solvent into the open end of the housing. A sensor and a processor can be provided to monitor and maintain a liquid dome present at the open end.

Research Organization:
Oak Ridge National Laboratory (ORNL), Oak Ridge, TN (United States)
Sponsoring Organization:
USDOE
DOE Contract Number:
AC05-00OR22725
Assignee:
UT-Battelle, LLC (Oak Ridge, TN)
Patent Number(s):
11,313,841
Application Number:
17/147,450
OSTI ID:
1892871
Country of Publication:
United States
Language:
English

References (4)

Capillary electrophoresis in an extended nanospray tip–electrospray as an electrophoretic column journal April 2015
A Falling Drop for Sample Injection in Capillary Zone Electrophoresis journal March 1997
An open port sampling interface for liquid introduction atmospheric pressure ionization mass spectrometry: Open port sampling interface journal August 2015
Transmission geometry laser ablation into a non-contact liquid vortex capture probe for mass spectrometry imaging
  • Ovchinnikova, Olga S.; Bhandari, Deepak; Lorenz, Matthias
  • Rapid Communications in Mass Spectrometry, Vol. 28, Issue 15, p. 1665-1673 https://doi.org/10.1002/rcm.6946
journal June 2014

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