ActinoBase: tools and protocols for researchers working on Streptomyces and other filamentous actinobacteria

Feeney, Morgan Anne; Newitt, Jake Terry; Addington, Emily; Algora-Gallardo, Lis; Allan, Craig; Balis, Lucas; Birke, Anna S.; Castaño-Espriu, Laia; Charkoudian, Louise K.; Devine, Rebecca; Gayrard, Damien; Hamilton, Jacob; Hennrich, Oliver; Hoskisson, Paul A.; Keith-Baker, Molly; Klein, Joshua G.; Kruasuwan, Worarat; Mark, David R.; Mast, Yvonne; McHugh, Rebecca E.; McLean, Thomas C.; Mohit, Elmira; Munnoch, John T.; Murray, Jordan; Noble, Katie; Otani, Hiroshi; Parra, Jonathan; Pereira, Camila F.; Perry, Louisa; Pintor-Escobar, Linamaria; Pritchard, Leighton; Prudence, Samuel M. M.; Russell, Alicia H.; Schniete, Jana K.; Seipke, Ryan F.; Sélem-Mojica, Nelly; Undabarrena, Agustina; Vind, Kristiina; van Wezel, Gilles P.; Wilkinson, Barrie; Worsley, Sarah F.; Duncan, Katherine R.; Fernández-Martínez, Lorena T.; Hutchings, Matthew I.

doi:10.1099/mgen.0.000824

ActinoBase: tools and protocols for researchers working on Streptomyces and other filamentous actinobacteria

Journal Article · Fri Jul 01 00:00:00 EDT 2022 · Microbial Genomics

DOI:https://doi.org/10.1099/mgen.0.000824· OSTI ID:1881895

Feeney, Morgan Anne ^[1]; Newitt, Jake Terry ^[2]; Addington, Emily ^[1]; Algora-Gallardo, Lis ^[1]; Allan, Craig ^[3]; Balis, Lucas ^[2]; Birke, Anna S. ^[1]; Castaño-Espriu, Laia ^[1]; Charkoudian, Louise K. ^[4]; Devine, Rebecca ^[2]; Gayrard, Damien ^[2]; Hamilton, Jacob ^[2]; Hennrich, Oliver ^[5]; Hoskisson, Paul A. ^[1]; Keith-Baker, Molly ^[1]; Klein, Joshua G. ^[4]; Kruasuwan, Worarat ^[6]; Mark, David R. ^[1]; Mast, Yvonne ^[5]; McHugh, Rebecca E. ^[1] more »

Univ. of Strathclyde, Glasgow, Scotland (United Kingdom)
John Innes Centre, Norwich (United Kingdom)
Swansea Univ., Wales (United Kingdom)
Haverford College, PA (United States)
Leibniz Inst. for German Collection of Microorganisms and Cell Cultures GmbH (DSMZ), Braunschweig (Germany)
Mahidol Univ., Bangkok (Thailand)
Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)
Max Planck Institute for Chemical Ecology, Jena (Germany)
Edge Hill Univ., Ormskirk (United Kingdom)
Queen Mary Univ. of London (United Kingdom)
Colorifix Ltd, Norwich (United Kingdom)
University of Leeds (United Kingdom)
Univ. Nacional Autonoma de Mexico (UNAM), Michoacán (Mexico)
Universidad Tecnica Federico Santa Maria, Valparaiso (Chile)
Wageningen Univ. (Netherlands)
Leiden Univ. (Netherlands)
Univ. of East Anglia, Norwich (United Kingdom)

Actinobacteria is an ancient phylum of Gram-positive bacteria with a characteristic high GC content to their DNA. The ActinoBase Wiki is focused on the filamentous actinobacteria, such as Streptomyces species, and the techniques and growth conditions used to study them. These organisms are studied because of their complex developmental life cycles and diverse specialised metabolism which produces many of the antibiotics currently used in the clinic. ActinoBase is a community effort that provides valuable and freely accessible resources, including protocols and practical information about filamentous actinobacteria. It is aimed at enabling knowledge exchange between members of the international research community working with these fascinating bacteria. ActinoBase is an anchor platform that underpins worldwide efforts to understand the ecology, biology and metabolic potential of these organisms. There are two key differences that set ActinoBase apart from other Wiki-based platforms: [1] ActinoBase is specifically aimed at researchers working on filamentous actinobacteria and is tailored to help users overcome challenges working with these bacteria and [2] it provides a freely accessible resource with global networking opportunities for researchers with a broad range of experience in this field.

View Accepted Manuscript (DOE)

Research Organization:: Lawrence Berkeley National Laboratory (LBNL), Berkeley, CA (United States)

Sponsoring Organization:: USDOE Office of Science (SC); National Science Foundation (NSF); Natural Environment Research Council (NERC); UK Research and Innovation (UKRI); Biotechnology and Biological Sciences Research Council (BBSRC); European Research Council (ERC); The Ministry of Science, Technology and Telecommunications of Costa Rica (MICITT); Medical Research Council; Royal Society Newton Fund

Grant/Contract Number:: AC02-05CH11231

OSTI ID:: 1881895

Journal Information:: Microbial Genomics, Journal Name: Microbial Genomics Journal Issue: 7 Vol. 8; ISSN 2057-5858

Publisher:: Society for General MicrobiologyCopyright Statement

Country of Publication:: United States

Language:: English

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59 BASIC BIOLOGICAL SCIENCES
BGCs
CRISPR
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actinobacteria
antibiotics
specialised metabolites

ActinoBase: tools and protocols for researchers working on Streptomyces and other filamentous actinobacteria

Citation Formats

References (79)

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