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Identifying Structural Determinants of Product Specificity in Leishmania major Farnesyl Diphosphate Synthase

Journal Article · · Biochemistry
; ; ; ; ;
Research Organization:
Brookhaven National Laboratory (BNL), Upton, NY (United States)
Sponsoring Organization:
~OTHER
DOE Contract Number:
SC0012704
OSTI ID:
1880656
Report Number(s):
BNL-221065-0001-JACI
Journal Information:
Biochemistry, Journal Name: Biochemistry Journal Issue: 29 Vol. 59; ISSN 0006-2960
Country of Publication:
United States
Language:
English

References (37)

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Structure and mechanism of the farnesyl diphosphate synthase from Trypanosoma cruzi: Implications for drug design journal November 2005
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Design, Synthesis, Calorimetry, and Crystallographic Analysis of 2-Alkylaminoethyl-1,1-bisphosphonates as Inhibitors of Trypanosoma cruzi Farnesyl Diphosphate Synthase journal July 2012
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Pyridinium-1-yl Bisphosphonates Are Potent Inhibitors of Farnesyl Diphosphate Synthase and Bone Resorption journal March 2005

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