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Iron deficiency impairs contractility of human cardiomyocytes through decreased mitochondrial function: Impaired contractility in iron-deficient cardiomyocytes
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February 2018 |
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Translocation of iron from lysosomes into mitochondria is a key event during oxidative stress-induced hepatocellular injury
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July 2008 |
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Decreased Hepatocyte Autophagy Leads to Synergistic IL‐1β and TNF Mouse Liver Injury and Inflammation
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June 2020 |
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Sex‐Specific Regulation of Interferon‐γ Cytotoxicity in Mouse Liver by Autophagy
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August 2021 |
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A precious metal: Iron, an essential nutrient for all cells
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March 2006 |
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Iron-induced generation of mitochondrial ROS depends on AMPK activity
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June 2017 |
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Iron in Health and Disease: An Update
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September 2019 |
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An Integrated Stress Response Regulates Amino Acid Metabolism and Resistance to Oxidative Stress
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March 2003 |
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The effects of iron overload on mitochondrial function, mitochondrial dynamics, and ferroptosis in cardiomyocytes
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February 2020 |
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Lipid-Induced Endoplasmic Reticulum Stress Impairs Selective Autophagy at the Step of Autophagosome-Lysosome Fusion in Hepatocytes
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July 2016 |
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Activation of apoptosis signalling pathways by reactive oxygen species
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December 2016 |
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The therapeutic effects of 4-phenylbutyric acid in maintaining proteostasis
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April 2015 |
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Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death
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May 2012 |
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A Red Carpet for Iron Metabolism
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January 2017 |
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Lethal Cardiomyopathy in Mice Lacking Transferrin Receptor in the Heart
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October 2015 |
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Roles of Fe–S proteins: from cofactor synthesis to iron homeostasis to protein synthesis
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June 2016 |
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Iron loading induces cholesterol synthesis and sensitizes endothelial cells to TNFα-mediated apoptosis
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October 2021 |
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Enteral ferric citrate absorption is dependent on the iron transport protein ferroportin
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April 2022 |
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Iron chelators induce autophagic cell death in multiple myeloma cells
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August 2014 |
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Roles of LAMP-1 and LAMP-2 in lysosome biogenesis and autophagy
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October 2006 |
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Distinct Autophagosomal-Lysosomal Fusion Mechanism Revealed by Thapsigargin-Induced Autophagy Arrest
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June 2011 |
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Role of Mitochondria in Ferroptosis
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January 2019 |
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Iron depletion increases manganese uptake and potentiates apoptosis through ER stress
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September 2013 |
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Mitochondrial iron–sulfur clusters: Structure, function, and an emerging role in vascular biology
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November 2021 |
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Ferroptosis is an autophagic cell death process
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August 2016 |
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Quantitative proteomics identifies NCOA4 as the cargo receptor mediating ferritinophagy
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March 2014 |
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ATF4 promotes angiogenesis and neuronal cell death and confers ferroptosis in a xCT-dependent manner
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May 2017 |
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DHODH-mediated ferroptosis defence is a targetable vulnerability in cancer
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May 2021 |
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Endoplasmic reticulum stress disrupts lysosomal homeostasis and induces blockade of autophagic flux in human trophoblasts
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August 2019 |
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Autophagy, mitochondria and oxidative stress: cross-talk and redox signalling
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December 2011 |
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Disrupted iron homeostasis causes dopaminergic neurodegeneration in mice
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February 2016 |
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Ferroptosis as a target for protection against cardiomyopathy
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January 2019 |
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Cystine/glutamate antiporter xCT (SLC7A11) facilitates oncogenic RAS transformation by preserving intracellular redox balance
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April 2019 |
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Iron deficiency and iron excess damage mitochondria and mitochondrial DNA in rats
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February 2002 |
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C/EBP Homologous Protein (CHOP) Contributes to Suppression of Metabolic Genes during Endoplasmic Reticulum Stress in the Liver
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February 2013 |
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Suppression of Lysosome Function Induces Autophagy via a Feedback Down-regulation of MTOR Complex 1 (MTORC1) Activity
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December 2013 |
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Mitochondrial Complex I Inhibitor Rotenone Induces Apoptosis through Enhancing Mitochondrial Reactive Oxygen Species Production
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December 2002 |
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Production of Reactive Oxygen Species by Mitochondria: CENTRAL ROLE OF COMPLEX III
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July 2003 |
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Acute loss of iron–sulfur clusters results in metabolic reprogramming and generation of lipid droplets in mammalian cells
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March 2018 |
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A genetic mouse model of severe iron deficiency anemia reveals tissue-specific transcriptional stress responses and cardiac remodeling
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October 2019 |
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ER stress: Autophagy induction, inhibition and selection
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November 2015 |
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Autophagy promotes ferroptosis by degradation of ferritin
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June 2016 |
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Iron overload causes endolysosomal deficits modulated by NAADP-regulated 2-pore channels and RAB7A
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July 2016 |
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Lysosome calcium in ROS regulation of autophagy
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August 2016 |
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Regulation of autophagy, mitochondrial dynamics, and cellular bioenergetics by 4-hydroxynonenal in primary neurons
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September 2017 |
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Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition) 1
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January 2021 |
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Multi-omics analysis identifies ATF4 as a key regulator of the mitochondrial stress response in mammals
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May 2017 |
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ATF4 is an oxidative stress–inducible, prodeath transcription factor in neurons in vitro and in vivo
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May 2008 |
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Oxidative Stress, Redox Signaling, and Autophagy: Cell Death Versus Survival
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July 2014 |
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Caveolin targeting to late endosome/lysosomal membranes is induced by perturbations of lysosomal pH and cholesterol content
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March 2012 |
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NEW EMBO MEMBERS' REVIEW: Lysosomal cysteine proteases: facts and opportunities
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September 2001 |
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Hyperglycemia promotes microvillus membrane expression of DMT1 in intestinal epithelial cells in a PKCα‐dependent manner
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November 2018 |
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Overview of iron metabolism in health and disease: Iron metabolism in health and disease
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March 2017 |
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TFEB Links Autophagy to Lysosomal Biogenesis
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May 2011 |
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Identification of the Iron-Responsive Element for the Translational Regulation of Human Ferritin mRNA
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December 1987 |
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Systemic Iron Homeostasis
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October 2013 |
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Iron Overload Damages the Endothelial Mitochondria via the ROS/ADMA/DDAHII/eNOS/NO Pathway
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November 2019 |
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Intralysosomal Iron Induces Lysosomal Membrane Permeabilization and Cathepsin D–Mediated Cell Death in Trabecular Meshwork Cells Exposed to Oxidative Stress
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December 2010 |
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Effects of maternal iron status on placental and fetal iron homeostasis
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December 2019 |
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Restoration of Na+/H+ exchanger NHE3-containing macrocomplexes ameliorates diabetes-associated fluid loss
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August 2015 |
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Mitochondria-dependent ferroptosis plays a pivotal role in doxorubicin cardiotoxicity
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May 2020 |
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Chronic Palmitate But Not Oleate Exposure Induces Endoplasmic Reticulum Stress, Which May Contribute to INS-1 Pancreatic β-Cell Apoptosis
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July 2006 |
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Biogenesis of iron-sulfur clusters in mammalian cells: new insights and relevance to human disease
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March 2012 |
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Chronic Iron Overload Results in Impaired Bacterial Killing of THP-1 Derived Macrophage through the Inhibition of Lysosomal Acidification
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May 2016 |
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The integrated stress response
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August 2016 |
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Iron overload inhibits late stage autophagic flux leading to insulin resistance
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August 2019 |
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Current understanding of iron homeostasis
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October 2017 |
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Dissecting the dynamic turnover of GFP-LC3 in the autolysosome
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February 2011 |
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Impaired lysosomal acidification triggers iron deficiency and inflammation in vivo
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December 2019 |