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Title: Physics-assisted generative adversarial network for X-ray tomography

Journal Article · · Optics Express
DOI:https://doi.org/10.1364/OE.460208· OSTI ID:1871842

X-ray tomography is capable of imaging the interior of objects in three dimensions non-invasively, with applications in biomedical imaging, materials science, electronic inspection, and other fields. The reconstruction process can be an ill-conditioned inverse problem, requiring regularization to obtain satisfactory results. Recently, deep learning has been adopted for tomographic reconstruction. Unlike iterative algorithms which require a distribution that is known a priori , deep reconstruction networks can learn a prior distribution through sampling the training distributions. In this work, we develop a Physics-assisted Generative Adversarial Network (PGAN), a two-step algorithm for tomographic reconstruction. In contrast to previous efforts, our PGAN utilizes maximum-likelihood estimates derived from the measurements to regularize the reconstruction with both known physics and the learned prior. Compared with methods with less physics assisting in training, PGAN can reduce the photon requirement with limited projection angles to achieve a given error rate. The advantages of using a physics-assisted learned prior in X-ray tomography may further enable low-photon nanoscale imaging.

Research Organization:
Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)
Sponsoring Organization:
USDOE National Nuclear Security Administration (NNSA); USDOE Advanced Research Projects Agency - Energy (ARPA-E); Singapore’s National Research Foundation; Office of the Director of National Intelligence (ODNI), Intelligence Advanced Research Projects Activity (IARPA)
Grant/Contract Number:
NA0003525; FA8050-17-C-9113; NRF2019-THE002-0006; D2019-1908080004; D2019-1906200003
OSTI ID:
1871842
Alternate ID(s):
OSTI ID: 1872055
Report Number(s):
SAND2022-7407J; OPEXFF
Journal Information:
Optics Express, Journal Name: Optics Express Vol. 30 Journal Issue: 13; ISSN 1094-4087
Publisher:
Optical Society of AmericaCopyright Statement
Country of Publication:
United States
Language:
English

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