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Structural basis for ligand reception by anaplastic lymphoma kinase

Journal Article · · Nature

Research Organization:
Argonne National Lab. (ANL), Argonne, IL (United States). Advanced Photon Source (APS)
Sponsoring Organization:
DOE - Office Of Science; NIGMS; National Institutes of Health (NIH)
OSTI ID:
1863995
Journal Information:
Nature, Vol. 600
Country of Publication:
United States
Language:
ENGLISH

References (38)

Anaplastic Lymphoma Kinase and Leukocyte Tyrosine Kinase: Functions and genetic interactions in learning, memory and adult neurogenesis journal January 2012
Identification of ALK in Thinness journal June 2020
Mechanistic insight into ALK receptor tyrosine kinase in human cancer biology journal September 2013
Antibody targeting of anaplastic lymphoma kinase induces cytotoxicity of human neuroblastoma journal January 2012
Identification of ALK as a major familial neuroblastoma predisposition gene journal August 2008
ALK in Neuroblastoma: Biological and Therapeutic Implications journal April 2018
ALK ligand ALKAL2 potentiates MYCN‐driven neuroblastoma in the absence of ALK mutation journal January 2021
Augmentor α and β (FAM150) are ligands of the receptor tyrosine kinases ALK and LTK: Hierarchy and specificity of ligand–receptor interactions journal November 2015
FAM150A and FAM150B are activating ligands for anaplastic lymphoma kinase journal September 2015
Cell Signaling by Receptor Tyrosine Kinases journal June 2010
A crucial role for the Anaplastic lymphoma kinase receptor tyrosine kinase in gut development in Drosophila melanogaster journal July 2003
Deorphanization of the human leukocyte tyrosine kinase (LTK) receptor by a signaling screen of the extracellular proteome journal October 2014
Identification of a biologically active fragment of ALK and LTK-Ligand 2 (augmentor-α) journal July 2018
Discovery of 7-(3-(piperazin-1-yl)phenyl)pyrrolo[2,1-f][1,2,4]triazin-4-amine derivatives as highly potent and selective PI3Kδ inhibitors journal February 2017
Construction of novel repeat proteins with rigid and predictable structures using a shared helix method journal June 2017
DALI and the persistence of protein shape journal November 2019
The Structure of Tumor Necrosis Factor-α at 2.6 Å Resolution journal October 1989
A rare polyglycine type II-like helix motif in naturally occurring proteins journal August 2017
Structure of Polyglycine II journal October 1955
Salmonella Phage S16 Tail Fiber Adhesin Features a Rare Polyglycine Rich Domain for Host Recognition journal December 2018
An antibody-drug conjugate directed to the ALK receptor demonstrates efficacy in preclinical models of neuroblastoma journal March 2019
COSMIC: the Catalogue Of Somatic Mutations In Cancer journal October 2018
HEN-1, a Secretory Protein with an LDL Receptor Motif, Regulates Sensory Integration and Learning in Caenorhabditis elegans journal May 2002
Jeb signals through the Alk receptor tyrosine kinase to drive visceral muscle fusion journal October 2003
Jelly belly protein activates the receptor tyrosine kinase Alk to specify visceral muscle pioneers journal October 2003
Heparin is an activating ligand of the orphan receptor tyrosine kinase ALK journal January 2015
Mechanism for the activation of the anaplastic lymphoma kinase receptor journal November 2021
Structural Basis of Neurohormone Perception by the Receptor Tyrosine Kinase Torso journal December 2015
Structural basis for EGFR ligand sequestration by Argos journal May 2008
Coot model-building tools for molecular graphics journal November 2004
Phaser crystallographic software journal July 2007
Automated macromolecular model building for X-ray crystallography using ARP/wARP version 7 journal June 2008
Macromolecular structure determination using X-rays, neutrons and electrons: recent developments in Phenix journal October 2019
Collaboration gets the most out of software journal September 2013
A general method to improve fluorophores for live-cell and single-molecule microscopy journal January 2015
XDS journal January 2010
Overview of the CCP 4 suite and current developments journal March 2011
The Phenix software for automated determination of macromolecular structures journal September 2011