Lung cancer and {sup 222}Rn-progeny-some methodological issues
Journal Article
·
· Transactions of the American Nuclear Society
OSTI ID:186234
- Univ. of Tennessee, Knoxville, TN (United States)
The correlation between the incidence of lung cancer and exposure to {sup 222}Rn daughters has been reviewed and evaluated comprehensively by the Biological Effects of Ionizing Radiation (BEIR) IV committee. A new National Research Council Committee. A new National Research Council Committee, BEIR VI, is taking another look at old and new data to derive new estimates of lung cancer risks for residential exposures. The {open_quotes}classical{close_quotes} approach to estimate the risks from residential {sup 222}Rn-daughter exposures is through extrapolation from followup studies of uranium and other hardrock miners. Direct estimation of residential risks is being done with case-control studies. The results of one such recent study do not {open_quotes}agree{close_quotes} with past risk estimates obtained via extrapolation. In the following sections we show by examining the methodology used for analyses that lung cancer risks from {sup 222}Rn progeny will always be surrounded by a degree of uncertainty and that this residual uncertainty is irreducible. Disagreement between point estimates of risks from different studies is therefore to be expected. This discussion will be limited mainly to followup studies.
- OSTI ID:
- 186234
- Report Number(s):
- CONF-950601--
- Journal Information:
- Transactions of the American Nuclear Society, Journal Name: Transactions of the American Nuclear Society Vol. 72; ISSN TANSAO; ISSN 0003-018X
- Country of Publication:
- United States
- Language:
- English
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