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Free radical formation in single crystals of 9-methyladenine X-irradiated at 10 K. An electron paramagnetic resonance and electron nuclear double resonance study

Journal Article · · Radiation Research
DOI:https://doi.org/10.2307/3578944· OSTI ID:186107
;  [1];  [2]
  1. Univ. of Oslo (Norway)
  2. Georgia State Univ., Atlanta, GA (United States); and others

Single crystals of 9-methyladenine were X-irradiated at 10 K and at 65 K and were studied using K-band EPR, ENDOR and field-swept ENDOR (FSE) techniques in the temperature range 10 K to 290 K. Three major radicals are stabilized in 9-methyladenine at 10 K. These are: MA1, the adenine anion, probably protonated at N3; MA2, the species formed by net hydrogen abstraction from the 9-methyl group; and MA3, the radical formed by net hydrogen addition to C8 of the adenine moiety. Radical MA1 decayed at about 80 K, possibly into the C2 H adduct (MA4). The other two species (MA2, MA3) were stable at room temperature. A fifth radical species was clearly present in the EPR spectra at 10 K but was not detectable by ENDOR. This species, which decayed above 200 K (possibly into MA3), remains unidentified. The radical population at room temperature is as described by previous authors. The mechanisms for radical formation in 9-methyladenine are discussed in light of the hydrogen bonding scheme and molecular stacking interactions. 32 refs., 4 figs., 2 tabs.

Sponsoring Organization:
USDOE
OSTI ID:
186107
Journal Information:
Radiation Research, Journal Name: Radiation Research Journal Issue: 3 Vol. 144; ISSN RAREAE; ISSN 0033-7587
Country of Publication:
United States
Language:
English

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