Localization of murine macrophage inducible nitric oxide synthase to mouse chromosome 11
- UCLA-DOE Lab. of Structural Biology and Molecular Medicine, Los Angeles, CA (United States); and others
There are at least three distinct nitric oxide (NO) synthase genes. Brain and endothelial NO synthases are constitutively synthesized, while NO synthase is inducible by cytokines in macrophages. We have utilized a backcross of (C57BL/6J x Mus spretus) x C57BL/6J to map the inducible NO synthase (Nos2). We report the chromosomal mapping of Nos2 to mouse chromosome 11, 3.3 cM proximal to Scya2. 10 refs., 1 tab.
- OSTI ID:
- 186038
- Journal Information:
- Genomics, Journal Name: Genomics Journal Issue: 3 Vol. 22; ISSN 0888-7543; ISSN GNMCEP
- Country of Publication:
- United States
- Language:
- English
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