Predictive Equations for Adult Pulmonary Function in Zhejiang Province, China
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- The First Affiliated Hospital of Wenzhou Medical University, Department of Respiratory and Critical Care Medicine, Shangcai Village, Nanbaixiang Street, Ouhai District, Wenzhou, Zhejiang Province 325006, China
- The First People’s Hospital in Jiaxing, Respiratory Department, 1882 Zhonghuan Nan Road, Nanhu District, Jiaxing, Zhejiang Province 314000, China
- The First People’s Hospital in Xiaoshan, Respiratory Department, 199 Shixin Middle Road, Xiaoshan District, Hangzhou, Zhejiang Province 311201, China
- The Central Hospital in Huzhou, Department of Respiratory and Critical Care Medicine, 198 Hongqi Road, Wuxing District, Huzhou, Zhejiang Province 313000, China
- The TCM Hospital of Zhejiang Province, Department of Pulmonary Function Examination, 54 Youdian Road, Shangcheng District, Hangzhou, Zhejiang Province 310000, China
- The Second Affiliated Hospital of Zhejiang University, Department of Respiratory and Critical Care Medicine, 88 Jiefang Road, Shangcheng District, HangZhou, Zhejiang Province 310009, China
- The Second Affiliated Hospital of Wenzhou Medical University, Department of Respiratory and Critical Care Medicine, 109 Xueyuan West Road, Lucheng District, Wenzhou, Zhejiang Province 325027, China
- The First Affiliated Hospital of Zhejiang University, Department of Respiratory and Critical Care Medicine, 79 Qingchun Road, Shangcheng District, HangZhou, Zhejiang Province 310009, China
- The Run Shaw Hospital of Zhejiang University, Department of Respiratory and Critical Care Medicine, 3 Qingchun East Road, Shangcheng District, HangZhou, Zhejiang Province 310036, China
- Zhejiang Hospital, Department of Respiratory Medicine, 1229 Gudun Road, Xihu District, Hangzhou, Zhejiang Province 310000, China
Background. Accurate interpretation of lung function tests requires appropriate spirometry reference values derived from large-scale population-specific epidemiological surveys. The aim of this cross-sectional study was to establish normal spirometric values for the population of healthy, nonsmoking Han Chinese adults residing in Zhejiang province, China. Methods. We measured lung function parameters such as forced expiratory volume in 1 s, forced vital capacity, peak expiratory flow, maximal midexpiratory flow, and diffusion capacity for carbon monoxide and considered age, height, and weight as independent factors that may modify these parameters. The clinical data were divided into the study arm and validation group. The study arms were used to construct predictive equations using stepwise multiple linear regression, and data from the validation group were used to assess the robustness of the equations. Results. The 3866 participants were randomized into a study arm (n = 1,949) and a validation arm (n = 1,917). Lung function parameters had a negative association with age and a positive association with height. Data from the two groups were similar. Predictive equations were constructed from the study arm, and the validation group was used to test the feasibility of the reference equations. Conclusions. The reference values we derived can be used to evaluate lung function in this cohort in both epidemiological studies and clinical practice.
- Sponsoring Organization:
- USDOE Office of Electricity (OE), Advanced Grid Research & Development. Power Systems Engineering Research
- Grant/Contract Number:
- 2016YFC1304000
- OSTI ID:
- 1856966
- Journal Information:
- Journal of Tropical Medicine, Journal Name: Journal of Tropical Medicine Vol. 2022; ISSN 1687-9686
- Publisher:
- Hindawi Publishing CorporationCopyright Statement
- Country of Publication:
- United Kingdom
- Language:
- English
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