Magnetic properties of γ-Fe 2 O 3 nanoparticles in a porous SiO 2 shell for drug delivery

Kamali, S.; Yu, E.; Bates, B.; McBride, J. R.; Johnson, C. E.; Taufour, V.; Stroeve, P.

doi:10.1088/1361-648x/abc403

Magnetic properties of γ-Fe ₂ O ₃ nanoparticles in a porous SiO ₂ shell for drug delivery

Journal Article · Thu Nov 12 23:00:00 EST 2020 · Journal of Physics. Condensed Matter

DOI:https://doi.org/10.1088/1361-648x/abc403· OSTI ID:1850455

^[1]; Yu, E.; Bates, B.; McBride, J. R.; Johnson, C. E.; Taufour, V.; Stroeve, P.

OSTI

A method is presented for synthesizing core–shell nanoparticles with a magnetic core and a porous shell suitable for drug delivery and other medical applications. The core contains multipleγ-Fe₂O₃nanoparticles (~15 nm) enclosed in a SiO₂(~100–200 nm) matrix using either methyl (denoted TMOS-γ-Fe₂O₃) or ethyl (TEOS-γ-Fe₂O₃) template groups. Low-temperature Mössbauer spectroscopy showed that the magnetic nanoparticles have the maghemite structure,γ-Fe₂O₃, with all the vacancies in the octahedral sites. Saturation magnetization measurements revealed that the density ofγ-Fe₂O₃was greater in the TMOS-γ-Fe₂O₃nanoparticles than TEOS-γ-Fe₂O₃nanoparticles, presumably because of the smaller methyl group. Magnetization measurements showed that the blocking temperature is around room temperature for the TMOS-γ-Fe₂O₃and around 250 K for the TEOS-γ-Fe₂O₃. Three dimensional topography analysis shows clearly that the magnetic nanoparticles are not only at the surface but have penetrated deep in the silica to form the core–shell structure.

Research Organization:: Univ. of California, Davis, CA (United States)

Sponsoring Organization:: USDOE Office of Nuclear Energy (NE)

DOE Contract Number:: NE0000704

OSTI ID:: 1850455

Journal Information:: Journal of Physics. Condensed Matter, Journal Name: Journal of Physics. Condensed Matter Journal Issue: 6 Vol. 33; ISSN 0953-8984

Publisher:: IOP Publishing

Country of Publication:: United States

Language:: English

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