Nano-FET-enabled biosensors: Materials perspective and recent advances in North America

Sedki, Mohammed; Shen, Yu; Mulchandani, Ashok

doi:10.1016/j.bios.2020.112941

Nano-FET-enabled biosensors: Materials perspective and recent advances in North America

Journal Article · Wed Dec 30 00:00:00 EST 2020 · Biosensors and Bioelectronics

DOI:https://doi.org/10.1016/j.bios.2020.112941· OSTI ID:1849236

Sedki, Mohammed ^[1]; Shen, Yu ^[2]; Mulchandani, Ashok ^[3]

Univ. of California, Riverside, CA (United States). Materials Science and Engineering Program; Univ. of California, Riverside, CA (United States)
Univ. of California, Riverside, CA (United States). Dept. of Chemical and Environmental Engineering
Univ. of California, Riverside, CA (United States). Dept. of Chemical and Environmental Engineering; Univ. of California, Riverside, CA (United States). Center for Environmental Research and Technology (CE-CERT)

Field-effect transistor (FET) is a very promising platform for biosensor applications due to its magnificent properties, including label-free detection, high sensitivity, fast response, real-time measurement capability, low running power, and the feasibility to miniaturize to a portable device. 1D (e.g. carbon nanotubes, Si nanowires, conductive polymer nanowires, 1D metal oxides, and others) and 2D (e.g. graphene materials, transition metal dichalcogenides, black phosphorus, and 2D metal oxides) materials, with their unique structural and electronic properties that are unavailable in bulk materials, have helped improve the sensitivity of FET biosensors and enabled detection down to single molecule. In this article, we give insights into the rapidly evolving field of 1D and 2D materials-based FET biosensors, with an emphasis on structure and electronic properties, synthesis, and biofunctionalization approaches of these nanomaterials. In addition, the progress in the 1D/2D-FET biosensors in North America, in the last decade, is summarized in tables. Moreover, challenges and future perspectives of 1D/2D-FET biosensors are covered.

View Accepted Manuscript (DOE)

Research Organization:: Univ. of California, Los Angeles, CA (United States)

Sponsoring Organization:: National Institutes of Justice; National Science Foundation (NSF); USDOE; USDOE Office of Fossil Energy (FE)

Grant/Contract Number:: FE0030456

OSTI ID:: 1849236

Alternate ID(s):: OSTI ID: 1778459

Journal Information:: Biosensors and Bioelectronics, Journal Name: Biosensors and Bioelectronics Journal Issue: C Vol. 176; ISSN 0956-5663

Publisher:: ElsevierCopyright Statement

Country of Publication:: United States

Language:: English

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