Incipient and Subclinical Tuberculosis: a Clinical Review of Early Stages and Progression of Infection
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journal
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July 2018 |
Functional Signatures of Human CD4 and CD8 T Cell Responses to Mycobacterium tuberculosis
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April 2014 |
Initiation of the adaptive immune response to Mycobacterium tuberculosis depends on antigen production in the local lymph node, not the lungs
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December 2007 |
A methodology for performing global uncertainty and sensitivity analysis in systems biology
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journal
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September 2008 |
BCG Educates Hematopoietic Stem Cells to Generate Protective Innate Immunity against Tuberculosis
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January 2018 |
Biomarkers of tuberculosis: a research roadmap
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June 2013 |
The spectrum of latent tuberculosis: rethinking the biology and intervention strategies
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journal
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October 2009 |
Mycobacterium tuberculosis-specific CD4 T cells expressing CD153 inversely associate with bacterial load and disease severity in human tuberculosis
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July 2020 |
Integrating Non-human Primate, Human, and Mathematical Studies to Determine the Influence of BCG Timing on H56 Vaccine Outcomes
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journal
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August 2018 |
CD4 + T Cells Contain Early Extrapulmonary Tuberculosis (TB) Dissemination and Rapid TB Progression and Sustain Multieffector Functions of CD8 + T and CD3 − Lymphocytes: Mechanisms of CD4 + T Cell Immunity
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journal
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January 2014 |
ICOS and Bcl6-dependent pathways maintain a CD4 T cell population with memory-like properties during tuberculosis
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April 2015 |
Contribution of CD8 + T Cells to Control of Mycobacterium tuberculosis Infection
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March 2006 |
Multiscale Computational Modeling Reveals a Critical Role for TNF-α Receptor 1 Dynamics in Tuberculosis Granuloma Formation
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February 2011 |
The End of the Binary Era: Revisiting the Spectrum of Tuberculosis
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October 2018 |
Simian Immunodeficiency Virus-Induced Changes in T Cell Cytokine Responses in Cynomolgus Macaques with Latent Mycobacterium tuberculosis Infection Are Associated with Timing of Reactivation
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journal
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February 2011 |
Both Pharmacokinetic Variability and Granuloma Heterogeneity Impact the Ability of the First-Line Antibiotics to Sterilize Tuberculosis Granulomas
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March 2020 |
Defining Memory CD8 T Cell
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November 2018 |
Dynamic balance of pro- and anti-inflammatory signals controls disease and limits pathology
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journal
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August 2018 |
Lymph nodes—The neglected battlefield in tuberculosis
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August 2020 |
A review of computational and mathematical modeling contributions to our understanding of Mycobacterium tuberculosis within-host infection and treatment
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journal
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June 2017 |
Concurrent infection with Mycobacterium tuberculosis confers robust protection against secondary infection in macaques
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October 2018 |
A Multi-Compartment Hybrid Computational Model Predicts Key Roles for Dendritic Cells in Tuberculosis Infection
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October 2016 |
Genomic diversity in autopsy samples reveals within-host dissemination of HIV-associated Mycobacterium tuberculosis
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October 2016 |
ESAT-6-specific CD4 T cell responses to aerosol Mycobacterium tuberculosis infection are initiated in the mediastinal lymph nodes
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July 2008 |
Defining features of protective CD4 T cell responses to Mycobacterium tuberculosis
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August 2014 |
Infection of Human Macrophages and Dendritic Cells with Mycobacterium tuberculosis Induces a Differential Cytokine Gene Expression That Modulates T Cell Response
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June 2001 |
Latent Tuberculosis Infection in the United States
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journal
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April 2011 |
Early Events in Mycobacterium tuberculosis Infection in Cynomolgus Macaques
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journal
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June 2006 |
Going beyond gamma for TB protection
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journal
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October 2018 |
Mycobacterium tuberculosis -specific CD8 + T cells are functionally and phenotypically different between latent infection and active disease: Immunity to infection
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journal
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June 2013 |
Whole-Blood Flow-Cytometric Analysis of Antigen-Specific CD4 T-Cell Cytokine Profiles Distinguishes Active Tuberculosis from Non-Active States
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March 2011 |
Global sensitivity analysis of biological multiscale models
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journal
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September 2019 |
Strategies for calibrating models of biology
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journal
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September 2018 |
Rhesus Macaques Are More Susceptible to Progressive Tuberculosis than Cynomolgus Macaques: a Quantitative Comparison
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journal
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September 2017 |
Tuberculosis: Back on the Immunologists' Agenda
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April 2006 |
Modelling the dynamics of tuberculosis lesions in a virtual lung: Role of the bronchial tree in endogenous reinfection
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journal
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May 2020 |
Tuberculosis: Latency and Reactivation
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journal
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July 2001 |
CD8 T cells and Mycobacterium tuberculosis infection
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journal
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April 2015 |
Digitally Barcoding Mycobacterium tuberculosis Reveals In Vivo Infection Dynamics in the Macaque Model of Tuberculosis
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journal
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May 2017 |
Lymph nodes are sites of prolonged bacterial persistence during Mycobacterium tuberculosis infection in macaques
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journal
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November 2018 |
Heterogeneity in tuberculosis
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journal
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July 2017 |
Identification of Probable Early-Onset Biomarkers for Tuberculosis Disease Progression
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September 2011 |
Using digital twins in viral infection
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March 2021 |
A systematic review of biomarkers to detect active tuberculosis
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journal
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February 2019 |
The evolution of the danger theory
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journal
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May 2012 |
Diagnosis and Treatment of Extrapulmonary Tuberculosis
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January 2015 |
The human immune response to Mycobacterium tuberculosis in lung and lymph node
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April 2004 |
Host resistance to pulmonary Mycobacterium tuberculosis infection requires CD153 expression
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journal
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September 2018 |
Why so many published sensitivity analyses are false: A systematic review of sensitivity analysis practices
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journal
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April 2019 |
Dendritic Cell Trafficking and Antigen Presentation in the Human Immune Response to Mycobacterium tuberculosis
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June 2004 |
Macrophages and control of granulomatous inflammation in tuberculosis
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journal
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March 2011 |
Modeling Tuberculosis in Nonhuman Primates
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journal
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September 2014 |
Prominent role for T cell-derived Tumour Necrosis Factor for sustained control of Mycobacterium tuberculosis infection
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May 2013 |
Assessment of treatment response in tuberculosis
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journal
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March 2016 |
Early Changes by 18Fluorodeoxyglucose Positron Emission Tomography Coregistered with Computed Tomography Predict Outcome after Mycobacterium tuberculosis Infection in Cynomolgus Macaques
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journal
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March 2014 |
Identifying control mechanisms of granuloma formation during M. tuberculosis infection using an agent-based model
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journal
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December 2004 |
New Paradigm for Translational Modeling to Predict Long-term Tuberculosis Treatment Response: Translational Modeling Predicts TB Treatment Response
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journal
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May 2017 |
Heterogeneity in tuberculosis pathology, microenvironments and therapeutic responses
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journal
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February 2015 |
Immunology studies in non-human primate models of tuberculosis
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journal
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February 2015 |
Neutrophils express pro- and anti-inflammatory cytokines in granulomas from Mycobacterium tuberculosis-infected cynomolgus macaques
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journal
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August 2019 |
Sterilization of granulomas is common in active and latent tuberculosis despite within-host variability in bacterial killing
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December 2013 |
Lesion-Specific Immune Response in Granulomas of Patients with Pulmonary Tuberculosis: A Pilot Study
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journal
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July 2015 |
Innate immunity in tuberculosis: host defense vs pathogen evasion
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journal
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September 2017 |
Biomarkers of Inflammation, Immunosuppression and Stress Are Revealed by Metabolomic Profiling of Tuberculosis Patients
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July 2012 |
Immune biomarkers: the promises and pitfalls of personalized medicine
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journal
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March 2015 |
Reactivation of Latent Tuberculosis in Cynomolgus Macaques Infected with SIV Is Associated with Early Peripheral T Cell Depletion and Not Virus Load
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March 2010 |
Digital twins to personalize medicine
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December 2019 |
Characterizing the BCG Induced Macrophage and Neutrophil Mechanisms for Defense Against Mycobacterium tuberculosis
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June 2020 |
Tuberculosis biomarkers discovery: developments, needs, and challenges
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April 2013 |
Global Burden of Tuberculosis: Estimated Incidence, Prevalence, and Mortality by Country
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August 1999 |
Variability in Tuberculosis Granuloma T Cell Responses Exists, but a Balance of Pro- and Anti-inflammatory Cytokines Is Associated with Sterilization
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journal
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January 2015 |
Harnessing donor unrestricted T-cells for new vaccines against tuberculosis
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journal
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May 2019 |
The Importance of First Impressions: Early Events in Mycobacterium tuberculosis Infection Influence Outcome
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journal
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April 2016 |
Comparing efficacies of moxifloxacin, levofloxacin and gatifloxacin in tuberculosis granulomas using a multi-scale systems pharmacology approach
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journal
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August 2017 |
Quantitative Comparison of Active and Latent Tuberculosis in the Cynomolgus Macaque Model
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journal
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July 2009 |
Measurement of leukocyte trafficking kinetics in macaques by serial intravascular staining
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journal
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January 2021 |
A Model to Predict Cell-Mediated Immune Regulatory Mechanisms During Human Infection with Mycobacterium tuberculosis
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journal
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February 2001 |
A computational model tracks whole-lung Mycobacterium tuberculosis infection and predicts factors that inhibit dissemination
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journal
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May 2020 |
Exhaled Mycobacterium tuberculosis output and detection of subclinical disease by face-mask sampling: prospective observational studies
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journal
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May 2020 |
Delayed protection by ESAT-6–specific effector CD4+ T cells after airborne M. tuberculosis infection
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journal
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September 2008 |
Computational Modeling Predicts IL-10 Control of Lesion Sterilization by Balancing Early Host Immunity–Mediated Antimicrobial Responses with Caseation during Mycobacterium tuberculosis Infection
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journal
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December 2014 |
Computational and Empirical Studies Predict Mycobacterium tuberculosis-Specific T Cells as a Biomarker for Infection Outcome
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journal
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April 2016 |
Immunological biomarkers of tuberculosis
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journal
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April 2011 |
Boosting BCG with proteins or rAd5 does not enhance protection against tuberculosis in rhesus macaques
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journal
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May 2019 |
Update on tuberculosis biomarkers: From correlates of risk, to correlates of active disease and of cure from disease: Tuberculosis biomarkers
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journal
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February 2018 |
A lung-on-chip model of early Mycobacterium tuberculosis infection reveals an essential role for alveolar epithelial cells in controlling bacterial growth
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November 2020 |