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Structural basis of binding and inhibition of ornithine decarboxylase by 1-amino-oxy-3-aminopropane

Journal Article · · Biochem. J.
DOI:https://doi.org/10.1042/BCJ20210647· OSTI ID:1839711

Research Organization:
Advanced Photon Source (APS), Argonne National Laboratory (ANL), Argonne, IL (US)
Sponsoring Organization:
DOE - Office Of Science; OTHER
OSTI ID:
1839711
Journal Information:
Biochem. J., Journal Name: Biochem. J. Journal Issue: (23) Vol. 478
Country of Publication:
United States
Language:
ENGLISH

References (40)

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Hydroxylamine-containing inhibitors of polyamine biosynthesis and impairment of colon cancer cell growth11Abbreviations: AMA, S-(5′-deoxy-5′-adenosyl)-methylthioethyl-hydroxylamine; APA, 1-aminooxy-3-aminopropane; DFMO, alpha-difluoromethylornithine; DMEM, Dulbecco’s modified Eagle’s medium; DTT, dithiothreitol; EGF, epidermal growth factor; 5-FU, 5-fluorouracil; LDH, lactate dehydrogenase; MGBG, methyl-bisguanylhydrazone; SAM, S-adenosylmethionine; SAMDC, S-adenosylmethionine decarboxylase; and ODC, ornithine decarboxylase. journal January 2001
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