Discovery and Optimization of DNA Gyrase and Topoisomerase IV Inhibitors with Potent Activity agains

Lapointe, Guillaume; Skepper, Colin K.; Holder, Lauren M.; Armstrong, Duncan; Bellamacina, Cornelia; Blais, Johanne; Bussiere, Dirksen; Bian, Jianwei; Cepura, Cody; Chan, Helen; Dean, Charles R.; De Pascale, Gianfranco; Dhumale, Bhavesh; Fisher, L. Mark; Fulsunder, Mangesh; Kantariya, Bhavin; Kim, Julie; King, Sean; Kossy, Lauren; Kulkarni, Upendra; Lakshman, Jay; Leeds, Jennifer A.; Ling, Xiaolan; Lvov, Anatoli; Ma, Sylvia; Malekar, Swapnil; McKenney, David; Mergo, Wosenu; Metzger, Louis; Mhaske, Keshav; Moser, Heinz E.; Mostafavi, Mina; Namballa, Sunil; Noeske, Jonas; Osborne, Colin; Patel, Ashish; Patel, Darshit; Patel, Tushar; Piechon, Philippe; Polyakov, Valery; Prajapati, Krunal; Prosen, Katherine R.; Reck, Folkert; Richie, Daryl L.; Sanderson, Mark R.; Satasia, Shailesh; Savani, Bhautik; Selvarajah, Jogitha; Sethuraman, Vijay; Shu, Wei; Tashiro, Kyuto; Thompson, Katherine V.; Vaarla, Krishniah; Vala, Lakhan; Veselkov, Dennis A.; Vo, Jason; Vora, Bhavesh; Wagner, Trixie; Wedel, Laura; Williams, Sarah L.; Yendluri, Satya; Yue, Qin; Yifru, Aregahegn; Zhang, Yong; Rivkin, Alexey

doi:10.1021/acs.jmedchem.1c00375

Discovery and Optimization of DNA Gyrase and Topoisomerase IV Inhibitors with Potent Activity agains

Journal Article · Thu Apr 01 00:00:00 EDT 2021 · J. Med. Chem.

DOI:https://doi.org/10.1021/acs.jmedchem.1c00375· OSTI ID:1834906

Lapointe, Guillaume; Skepper, Colin K.; Holder, Lauren M.; Armstrong, Duncan; Bellamacina, Cornelia; Blais, Johanne; Bussiere, Dirksen; Bian, Jianwei; Cepura, Cody; Chan, Helen; Dean, Charles R.; De Pascale, Gianfranco; Dhumale, Bhavesh; Fisher, L. Mark; Fulsunder, Mangesh; Kantariya, Bhavin; Kim, Julie; King, Sean; Kossy, Lauren; Kulkarni, Upendra more »

Research Organization:: Advanced Photon Source (APS), Argonne National Laboratory (ANL), Argonne, IL (US)

Sponsoring Organization:: DOE - Office Of Science; INDUSTRY

OSTI ID:: 1834906

Journal Information:: J. Med. Chem., Journal Name: J. Med. Chem. Journal Issue: (9) Vol. 64

Country of Publication:: United States

Language:: ENGLISH

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Preparation and Diels−Alder Reactivity of 1-Amino-3-siloxy-1,3-butadienes Kozmin, Sergey A.; Rawal, Viresh H. The Journal of Organic Chemistry, Vol. 62, Issue 16 https://doi.org/10.1021/jo970438q	journal	August 1997
Perfluoro- and polyfluorosulfonic acids. 21. Synthesis of difluoromethyl esters using fluorosulfonyldifluoroacetic acid as a difluorocarbene precursor Chen, Qingyun; Wu, Shengwen The Journal of Organic Chemistry, Vol. 54, Issue 13 https://doi.org/10.1021/jo00274a012	journal	June 1989

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