skip to main content
OSTI.GOV title logo U.S. Department of Energy
Office of Scientific and Technical Information

Title: Structural and functional divergence of GDAP1 from the glutathione S-transferase superfamily

Journal Article · · FASEB J.

Research Organization:
Argonne National Lab. (ANL), Argonne, IL (United States). Advanced Photon Source (APS)
Sponsoring Organization:
DOE - Office Of Science; National Institutes of Health (NIH)
OSTI ID:
1833685
Journal Information:
FASEB J., Vol. 34, Issue (5)
Country of Publication:
United States
Language:
ENGLISH

References (60)

Charcot Marie Tooth disease (CMT): historical perspectives and evolution journal September 2014
Neural and Molecular Features on Charcot-Marie-Tooth Disease Plasticity and Therapy journal January 2012
Charcot–Marie–Tooth disease and related disorders: an evolving landscape journal January 2019
Charcot–Marie–Tooth disease: frequency of genetic subtypes and guidelines for genetic testing journal May 2012
Plasma neurofilament heavy chain is not a useful biomarker in Charcot-Marie-Tooth disease: Neurofilament Heavy Chain in CMT journal April 2016
Clinical implications of genetic advances in Charcot–Marie–Tooth disease journal September 2013
A novel mutation in the FGD4 gene causing Charcot-Marie-Tooth disease: CMT and FGD4 gene mutations journal September 2017
The gene encoding ganglioside-induced differentiation-associated protein 1 is mutated in axonal Charcot-Marie-Tooth type 4A disease journal December 2001
Genotype–phenotype correlation and frequency of distribution in a cohort of Chinese Charcot–Marie–Tooth patients associated with GDAP1 mutations journal January 2018
Genetics of Charcot-Marie-Tooth disease type 4A: mutations, inheritance, phenotypic variability, and founder effect journal April 2005
Phenotypical features of the p.R120W mutation in the GDAP1 gene causing autosomal dominant Charcot-Marie-Tooth disease journal December 2010
Charcot-Marie-Tooth disease: Genetic and clinical spectrum in a Spanish clinical series journal September 2013
Ganglioside-induced differentiation-associated protein-1 is mutant in Charcot-Marie-Tooth disease type 4A/8q21 journal December 2001
Charcot Marie Tooth disease (CMT4A) due to GDAP1 mutation: report of a colombian family. journal December 2015
Mutations in the ganglioside-induced differentiation-associated protein-1 (GDAP1) gene in intermediate type autosomal recessive Charcot-Marie-Tooth neuropathy journal March 2003
Ganglioside-induced differentiation associated protein 1 is a regulator of the mitochondrial network journal September 2005
Charcot–Marie–Tooth disease CMT4A: GDAP1 increases cellular glutathione and the mitochondrial membrane potential journal September 2011
Cell expression of GDAP1 in the nervous system and pathogenesis of Charcot-Marie-Tooth type 4A disease journal April 2008
GDAP1, the protein causing Charcot–Marie–Tooth disease type 4A, is expressed in neurons and is associated with mitochondria journal March 2005
Targeting and Function of the Mitochondrial Fission Factor GDAP1 Are Dependent on Its Tail-Anchor journal April 2009
Charcot‐Marie‐Tooth disease‐associated mutants of GDAP1 dissociate its roles in peroxisomal and mitochondrial fission journal April 2013
GDAP1 mutations differ in their effects on mitochondrial dynamics and apoptosis depending on the mode of inheritance journal December 2009
CMT-linked loss-of-function mutations in GDAP1 impair store-operated Ca2+ entry-stimulated respiration journal February 2017
Silencing of the Charcot–Marie–Tooth disease-associated gene GDAP1 induces abnormal mitochondrial distribution and affects Ca2+ homeostasis by reducing store-operated Ca2+ entry journal July 2013
The Gdap1 knockout mouse mechanistically links redox control to Charcot–Marie–Tooth disease journal January 2014
Functional characterisation of ganglioside-induced differentiation-associated protein 1 as a glutathione transferase journal September 2006
Evolutionary and Structural Analyses of GDAP1, Involved in Charcot-Marie-Tooth Disease, Characterize a Novel Class of Glutathione Transferase-Related Genes journal October 2003
The Three-Dimensional Structure of the Human Pi Class Glutathione Transferase P1-1 in Complex with the Inhibitor Ethacrynic Acid and Its Glutathione Conjugate , journal January 1997
The glutathione conjugate of ethacrynic acid can bind to human pi class glutathione transferase P1-1 in two different modes journal December 1997
Glutathione transferases: a structural perspective journal March 2011
The three-dimensional structure of class pi glutathione S-transferase in complex with glutathione sulfonate at 2.3 A resolution. journal August 1991
Glutathione Transferases journal September 2005
Oxidative stress and lipotoxicity journal November 2016
Regulation of rat glutathione S-transferase A5 by cancer chemopreventive agents: Mechanisms of inducible resistance to aflatoxin B1 journal April 1998
Glutathione-conjugating and membrane-remodeling activity of GDAP1 relies on amphipathic C-terminal domain journal November 2016
Protein production by auto-induction in high-density shaking cultures journal May 2005
Data processing and analysis with the autoPROC toolbox journal March 2011
Features and development of Coot journal March 2010
PHENIX: a comprehensive Python-based system for macromolecular structure solution journal January 2010
Loss of TRPML1 promotes production of reactive oxygen species: is oxidative damage a factor in mucolipidosis type IV? journal December 2013
Rapid force generation is impaired in cerebral palsy and is related to decreased muscle size and functional mobility journal January 2012
New crystal structures of human glutathione transferase A1-1 shed light on glutathione binding and the conformation of the C-terminal helix journal January 2006
Crystallographic and Thermodynamic Analysis of the Binding of S -Octylglutathione to the Tyr 7 to Phe Mutant of Glutathione S -Transferase from Schistosoma japonicum , journal January 2005
Thermodynamic Description of the Effect of the Mutation Y49F on Human Glutathione Transferase P1-1 in Binding with Glutathione and the Inhibitor S-Hexylglutathione journal November 2003
Thermodynamic analysis of the binding of glutathione to glutathione S -transferase over a range of temperatures: Thermodynamic of GSH binding to GST journal August 2001
A calorimetric study of the binding of S-alkylglutathiones to glutathione S-transferase journal July 2001
Structural analysis of human alpha-class glutathione transferase A1-1 in the apo-form and in complexes with ethacrynic acid and its glutathione conjugate journal July 1995
Influence of the H-site residue 108 on human glutathione transferase P1-1 ligand binding: Structure-thermodynamic relationships and thermal stability journal December 2009
Diuretic drug binding to human glutathione transferase P1-1: potential role of Cys-101 revealed in the double mutant C47S/Y108V journal February 2011
Eukaryotic translation elongation factor 1γ contains a glutathione transferase domain-Study of a diverse, ancient protein super family using motif search and structural modeling journal November 1994
Charcot-Marie-Tooth-related Gene GDAP1 Complements Cell Cycle Delay at G2/M Phase in Saccharomyces cerevisiae fis1 Gene-defective Cells journal October 2011
Protein Structure and Function Prediction Using I‐TASSER journal December 2015
Template-based protein structure prediction in CASP11 and retrospect of I-TASSER in the last decade: Template-Based Structure Prediction in CASP11 journal September 2015
I-TASSER server: new development for protein structure and function predictions journal April 2015
Structural Basis of Stereospecificity in the Bacterial Enzymatic Cleavage of β-Aryl Ether Bonds in Lignin journal December 2015
A role for the GDAP1 gene in the molecular pathogenesis of Charcot-Marie-Tooth disease journal January 2018
Mitochondrial dysfunction and pathophysiology of Charcot–Marie–Tooth disease involving GDAP1 mutations journal January 2011
Lack of GDAP1 Induces Neuronal Calcium and Mitochondrial Defects in a Knockout Mouse Model of Charcot-Marie-Tooth Neuropathy journal April 2015
Fiji: an open-source platform for biological-image analysis journal June 2012
The combined use of photoaffinity labeling and surface plasmon resonance-based technology identifies multiple salicylic acid-binding proteins journal October 2012