Discovery of 2-amino-3-amido-5-aryl-pyridines as highly potent, orally bioavailable, and efficacious

Calvo, Veronica; Surguladze, David; Li, An-Hu; Surman, Matthew D.; Malibhatla, Srikanth; Bandaru, Madhavarao; Jonnalagadda, Suresh Krishna; Adarasandi, Ravi; Velmala, Madhusudhan; Singireddi, Durga Rama Prasad; Velpuri, Mahendar; Nareddy, Bhaskar Reddy; Sastry, Visweswara; Mandati, Chiranjeevi; Guguloth, Rambabu; Siddiqui, Shapi; Patil, Basanagoud S.; Chad, Elena; Wolfley, Jennifer; Gasparek, Jennifer; Feldman, Kirsten; Betzenhauser, Matthew; Wiens, Brent; Koszelak-Rosenblum, Mary; Zhu, Guangyu; Du, Hongwen; Rigby, Alan C.; Mulvihill, Mark J.

doi:10.1016/j.bmcl.2021.128058

Discovery of 2-amino-3-amido-5-aryl-pyridines as highly potent, orally bioavailable, and efficacious

Journal Article · Thu Jul 01 04:00:00 EDT 2021 · Bioorg. Med. Chem. Lett.

DOI:https://doi.org/10.1016/j.bmcl.2021.128058· OSTI ID:1832564

Calvo, Veronica; Surguladze, David; Li, An-Hu; Surman, Matthew D.; Malibhatla, Srikanth; Bandaru, Madhavarao; Jonnalagadda, Suresh Krishna; Adarasandi, Ravi; Velmala, Madhusudhan; Singireddi, Durga Rama Prasad; Velpuri, Mahendar; Nareddy, Bhaskar Reddy; Sastry, Visweswara; Mandati, Chiranjeevi; Guguloth, Rambabu; Siddiqui, Shapi; Patil, Basanagoud S.; Chad, Elena; Wolfley, Jennifer; Gasparek, Jennifer more »

Research Organization:: Advanced Photon Source (APS), Argonne National Laboratory (ANL), Argonne, IL (US)

Sponsoring Organization:: DOE - Office Of Science; NIH

OSTI ID:: 1832564

Journal Information:: Bioorg. Med. Chem. Lett., Journal Name: Bioorg. Med. Chem. Lett. Vol. 43

Country of Publication:: United States

Language:: ENGLISH

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