Skip to main content
U.S. Department of Energy
Office of Scientific and Technical Information

A continuous flow chemistry approach for the ultrafast and low-cost synthesis of MOF-808

Journal Article · · Green Chemistry
DOI:https://doi.org/10.1039/D1GC02824C· OSTI ID:1830848
 [1];  [2];  [3];  [4];  [5]
  1. Department of Mechanical Engineering, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, Massachusetts 02139, USA, Department of Chemical Engineering, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, Massachusetts 02139, USA
  2. Department of Chemical Engineering, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, Massachusetts 02139, USA, Department of Materials Science and Engineering, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, Massachusetts 02139, USA
  3. Instituto de Tecnología Química, UPV-CSIC, Universitat Politècnica de València-Consejo Superior de Investigaciones Científicas, Avenida de los Naranjos s/n, 46022 Valencia, Spain
  4. Department of Mechanical Engineering, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, Massachusetts 02139, USA, Department of Materials Science and Engineering, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, Massachusetts 02139, USA
  5. Department of Chemical Engineering, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, Massachusetts 02139, USA

The continous flow reactor can synthesize MOF-808—an industrially relevant MOF—in 5 minutes compared to 48 hours in Batch, while maintaining crystallinity and porosity of the final product.

Research Organization:
Massachusetts Institute of Technology (MIT), Cambridge, MA (United States)
Sponsoring Organization:
USDOE; USDOE Office of Science (SC), Basic Energy Sciences (BES)
Grant/Contract Number:
SC0016214
OSTI ID:
1830848
Alternate ID(s):
OSTI ID: 1978792
Journal Information:
Green Chemistry, Journal Name: Green Chemistry Journal Issue: 24 Vol. 23; ISSN GRCHFJ; ISSN 1463-9262
Publisher:
Royal Society of Chemistry (RSC)Copyright Statement
Country of Publication:
United Kingdom
Language:
English

References (66)

Stable Metal-Organic Frameworks: Design, Synthesis, and Applications journal February 2018
Reactions in Droplets in Microfluidic Channels journal November 2006
Continuous Heterogeneous Photocatalysis in Serial Micro-Batch Reactors journal March 2018
Harsh Reaction Conditions in Continuous-Flow Microreactors for Pharmaceutical Production journal November 2009
Liquid/Liquid Slug Flow Capillary Microreactor journal January 2011
Modulated Synthesis of Zr-Based Metal-Organic Frameworks: From Nano to Single Crystals journal May 2011
Continuous Flow Synthesis of a Zr Magnetic Framework Composite for Post‐Combustion CO 2 Capture journal September 2019
Green and Sustainable Chemical Synthesis Using Flow Microreactors journal November 2010
Scalability of Continuous Flow Production of Metal-Organic Frameworks journal April 2016
A Facile “Green” Route for Scalable Batch Production and Continuous Synthesis of Zirconium MOFs: A Facile “Green” Route for Scalable Batch Production and Continuous Synthesis of Zirconium MOFs journal June 2016
Polymer chemistry in flow: New polymers, beads, capsules, and fibers journal January 2006
Flow chemistry using milli- and microstructured reactors—From conventional to novel process windows journal June 2010
Continuous synthesis for zirconium metal-organic frameworks with high quality and productivity via microdroplet flow reaction journal June 2018
Hydrodynamics of liquid–liquid slug flow capillary microreactor: Flow regimes, slug size and pressure drop journal July 2007
Continuous flow production of metal-organic frameworks journal May 2015
Synthesis and characterization of porous HKUST-1 metal organic frameworks for hydrogen storage journal September 2012
Quest for pore size effect on the catalytic property of defect-engineered MOF-808-SO4 in the addition reaction of isobutylene with ethylene glycol journal January 2019
Facile synthesis of metal-organic framework MOF-808 for arsenic removal journal December 2015
Solvothermal Crystallization Kinetics and Control of Crystal Size Distribution of MOF-808 in a Continuous Flow Reactor journal October 2021
Development of a Cambridge Structural Database Subset: A Collection of Metal–Organic Frameworks for Past, Present, and Future journal March 2017
Techno-economic Analysis of Metal–Organic Frameworks for Hydrogen and Natural Gas Storage journal January 2017
MOF-808: A Metal–Organic Framework with Intrinsic Peroxidase-Like Catalytic Activity at Neutral pH for Colorimetric Biosensing journal July 2018
Grand Challenges and Future Opportunities for Metal–Organic Frameworks journal June 2017
Scalable Continuous Flow Metal–Organic Framework (MOF) Synthesis Using Supercritical CO 2 journal June 2020
Accelerated Synthesis of a Ni 2 Cl 2 (BTDD) Metal–Organic Framework in a Continuous Flow Reactor for Atmospheric Water Capture journal March 2021
A Facile in Situ Self-Assembly Strategy for Large-Scale Fabrication of CHS@MOF Yolk/Shell Structure and Its Catalytic Application in a Flow System journal February 2015
Colloidal-Sized Metal–Organic Frameworks: Synthesis and Applications journal December 2013
Disclosing the Complex Structure of UiO-66 Metal Organic Framework: A Synergic Combination of Experiment and Theory journal April 2011
Metal–Organic Frameworks in Biomedicine journal September 2011
Introduction to Metal–Organic Frameworks journal September 2011
Scaleup of Batch Reactors Using Phenomenological-Based Models
  • Monsalve-Bravo, Gloria M.; Moscoso-Vasquez, Hilda M.; Alvarez, Hernan
  • Industrial & Engineering Chemistry Research, Vol. 53, Issue 22 https://doi.org/10.1021/ie500587r
journal May 2014
Water Adsorption in Porous Metal–Organic Frameworks and Related Materials journal March 2014
Superacidity in Sulfated Metal–Organic Framework-808 journal September 2014
Observing the Growth of Metal–Organic Frameworks by in Situ Liquid Cell Transmission Electron Microscopy journal June 2015
Application of Consistency Criteria To Calculate BET Areas of Micro- And Mesoporous Metal–Organic Frameworks journal December 2015
Bioinspired Metal–Organic Framework Catalysts for Selective Methane Oxidation to Methanol journal December 2018
Design of Experiments (DoE) and Process Optimization. A Review of Recent Publications journal August 2014
A flow-microreactor approach to protecting-group-free synthesis using organolithium compounds journal April 2011
A versatile MOF-based trap for heavy metal ion capture and dispersion journal January 2018
Identification of the strong Brønsted acid site in a metal–organic framework solid acid catalyst journal November 2018
A Design of Experiments (DoE) Approach Accelerates the Optimization of Copper-Mediated 18F-Fluorination Reactions of Arylstannanes journal August 2019
Multiphase microfluidics: from flow characteristics to chemical and materials synthesis journal January 2006
Metal–organic framework materials as catalysts journal January 2009
Crystallisation of solvothermally synthesised ZIF-8 investigated at the bulk, single crystal and surface level journal January 2013
Tuning pore size in a zirconium–tricarboxylate metal–organic framework journal January 2014
Insight into the mechanism of modulated syntheses: in situ synchrotron diffraction studies on the formation of Zr-fumarate MOF journal January 2014
Synthesis of metal–organic frameworks by continuous flow journal January 2014
Gas–liquid segmented flow microwave-assisted synthesis of MOF-74(Ni) under moderate pressures journal January 2015
Zr-based metal–organic frameworks: design, synthesis, structure, and applications journal January 2016
Catalytic test reactions for the evaluation of hierarchical zeolites journal January 2016
Flow-synthesis of carboxylate and phosphonate based metal–organic frameworks under non-solvothermal reaction conditions journal January 2015
The application of design of experiments (DoE) reaction optimisation and solvent selection in the development of new synthetic chemistry journal January 2016
Progress of crystallization in microfluidic devices journal January 2017
Towards scalable and controlled synthesis of metal–organic framework materials using continuous flow reactors journal January 2016
Engineering chemistry: integrating batch and flow reactions on a single, automated reactor platform journal January 2016
New synthetic routes towards MOF production at scale journal January 2017
Synthesis, functionalization, and applications of metal–organic frameworks in biomedicine journal January 2018
Metal–organic frameworks supported on nanofibers to remove heavy metals journal January 2018
Zr-MOF-808@MCM-41 catalyzed phosgene-free synthesis of polyurethane precursors journal January 2019
Ultrafast synthesis of zeolites: breakthrough, progress and perspective journal January 2019
Continuous flow synthesis of ordered porous materials: from zeolites to metal–organic frameworks and mesoporous silica journal January 2019
Process-Based Cost Modeling journal March 2007
On-demand continuous-flow production of pharmaceuticals in a compact, reconfigurable system journal March 2016
Design and Scaling Up of Microchemical Systems: A Review journal June 2017
Physisorption of gases, with special reference to the evaluation of surface area and pore size distribution (IUPAC Technical Report) journal October 2015
Cost Analysis for a Continuously Operated Fine Chemicals Production Plant at 10 Kg/Day Using a Combination of Microprocessing and Microwave Heating journal December 2011

Similar Records

Densification Pressure Optimization of MOF-808-Based Membranes for Lithium Metal Batteries
Journal Article · Sun Dec 10 19:00:00 EST 2023 · ACS Applied Energy Materials · OSTI ID:2447333

Vapor Phase Installation of CpCo(CO)2 in MOF‐808
Journal Article · Mon Jul 07 20:00:00 EDT 2025 · Advanced Materials Interfaces · OSTI ID:2574935