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LPS, dsRNA and the interferon bridge to adaptive immune responses: Trif, Tram, and other TIR adaptor proteins
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Quantification of sulfatides and lysosulfatides in tissues and body fluids by liquid chromatography-tandem mass spectrometry
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Reconstruction of LPS Transfer Cascade Reveals Structural Determinants within LBP, CD14, and TLR4-MD2 for Efficient LPS Recognition and Transfer
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January 2017 |
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Postulates for validating TLR4 agonists: Highlights
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January 2015 |
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Saturation of acyl chains converts cardiolipin from an antagonist to an activator of Toll-like receptor-4
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May 2019 |
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Crystal Structures of Human MD-2 and Its Complex with Antiendotoxic Lipid IVa
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June 2007 |
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Antibodies to sulfatide in cerebrospinal fluid of patients with multiple sclerosis
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June 2003 |
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Globo-series glycosphingolipids enhance Toll-like receptor 4-mediated inflammation and play a pathophysiological role in diabetic nephropathy
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December 2018 |
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Quantitative imaging mass spectrometry of renal sulfatides: validation by classical mass spectrometric methods
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PHENIX: a comprehensive Python-based system for macromolecular structure solution
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The Existence of Galactosylceramide I3-Sulfate in Serums of Various Mammals and Its Anticoagulant Activity1
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Intracellular sulfatide expression in a subpopulation of astrocytes in primary cultures
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End-Point Binding Free Energy Calculation with MM/PBSA and MM/GBSA: Strategies and Applications in Drug Design
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HKL -3000: the integration of data reduction and structure solution – from diffraction images to an initial model in minutes
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Chemistry and functional distribution of sulfoglycolipids
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Levels of plasma sulfatides C18 : 0 and C24 : 1 correlate with disease status in relapsing-remitting multiple sclerosis
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Structural Basis of TLR2/TLR1 Activation by the Synthetic Agonist Diprovocim
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Toll-like Receptor 9 Contains Two DNA Binding Sites that Function Cooperatively to Promote Receptor Dimerization and Activation
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The long and the short of ceramides
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June 2018 |
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Sulfatide is a negative regulator of oligodendrocyte differentiation: Development in sulfatide-null mice
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Synthetic isoforms of endogenous sulfatides differently modulate indoleamine 2,3-dioxygenase in antigen presenting cells
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Development and testing of a general amber force field
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Role of CREB in modulation of TNFα and IL-10 expression in LPS-stimulated RAW264.7 macrophages
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Sulfatides trigger cytokine gene expression and secretion in human monocytes
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Expression of the myelin and oligodendrocyte progenitor marker sulfatide in neurons and astrocytes of adult rat brain
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Self-Glycolipids Modulate Dendritic Cells Changing the Cytokine Profiles of Committed Autoreactive T Cells
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TLR4/MD-2 activation by a synthetic agonist with no similarity to LPS
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Assessing the Performance of the MM/PBSA and MM/GBSA Methods. 1. The Accuracy of Binding Free Energy Calculations Based on Molecular Dynamics Simulations
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MD-2-mediated Ionic Interactions between Lipid A and TLR4 Are Essential for Receptor Activation
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March 2010 |
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Substantial sulfatide deficiency and ceramide elevation in very early Alzheimer's disease: potential role in disease pathogenesis: Sulfatide deficiency and ceramide elevation in AD
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New tricks for modelers from the crystallography toolkit: the particle mesh Ewald algorithm and its use in nucleic acid simulations
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Linearization of the Bradford Protein Assay Increases Its Sensitivity: Theoretical and Experimental Studies
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Crystal Structure of the TLR4-MD-2 Complex with Bound Endotoxin Antagonist Eritoran
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Lipid microarrays identify key mediators of autoimmune brain inflammation
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Adjuvant effect of the novel TLR1/TLR2 agonist Diprovocim synergizes with anti–PD-L1 to eliminate melanoma in mice
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Renal sulfatides: sphingoid base-dependent localization and region-specific compensation of CerS2-dysfunction
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Mammalian Lass6 and its related family members regulate synthesis of specific ceramides
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Endogenous toll-like receptor ligands and their biological significance
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TLR4-MD-2 complex is negatively regulated by an endogenous ligand, globotetraosylceramide
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The Structural Biology of Toll-like Receptors
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Coot model-building tools for molecular graphics
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Prevention of Autoimmunity by Targeting a Distinct, Noninvariant CD1d-reactive T Cell Population Reactive to Sulfatide
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Activation of c-Jun N-terminal kinase in bacterial lipopolysaccharide-stimulated macrophages.
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Recombinant Human Heat Shock Protein 60 Does Not Induce the Release of Tumor Necrosis Factor α from Murine Macrophages
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Quantitative analysis of sphingolipids for lipidomics using triple quadrupole and quadrupole linear ion trap mass spectrometers
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MyD88: a central player in innate immune signaling
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Role of sulfatide in normal and pathological cells and tissues
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Altered lipid levels provide evidence for myelin dysfunction in multiple system atrophy
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Dendritic Cells and Anergic Type I NKT Cells Play a Crucial Role in Sulfatide-Mediated Immune Regulation in Experimental Autoimmune Encephalomyelitis
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Mammalian ceramide synthases
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Role of Adaptor TRIF in the MyD88-Independent Toll-Like Receptor Signaling Pathway
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The TLR4 antagonist Eritoran protects mice from lethal influenza infection
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Sulfatide, A Major Lipid Component of Myelin Sheath, Activates Inflammatory Responses As an Endogenous Stimulator in Brain-Resident Immune Cells
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Treatment with Sulfatide or its Precursor, Galactosylceramide, Prevents Diabetes in NOD Mice
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Sulfatide Inhibits HMGB1 Secretion by Hindering Toll-Like Receptor 4 Localization Within Lipid Rafts
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The structural basis of lipopolysaccharide recognition by the TLR4–MD-2 complex
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The ins and outs of sphingolipid synthesis
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Structural basis of species-specific endotoxin sensing by innate immune receptor TLR4/MD-2
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