skip to main content
OSTI.GOV title logo U.S. Department of Energy
Office of Scientific and Technical Information

Title: Explainable Artificial Intelligence Recommendation System by Leveraging the Semantics of Adverse Childhood Experiences: Proof-of-Concept Prototype Development

Journal Article · · JMIR medical informatics
DOI:https://doi.org/10.2196/18752· OSTI ID:1815906
ORCiD logo [1]; ORCiD logo [2]
  1. Univ. of Tennessee Health Science Center - Oak Ridge National Lab., Memphis, TN (United States). College of Medicine. Center for Biomedical Informatics. Dept. of Pediatrics
  2. Univ. of Tennessee Health Science Center - Oak Ridge National Lab., Memphis, TN (United States). College of Medicine. Center for Biomedical Informatics. Dept. of Pediatrics

The study of adverse childhood experiences and their consequences has emerged over the past 20 years. Although the conclusions from these studies are available, the same is not true of the data. Accordingly, it is a complex problem to build a training set and develop machine-learning models from these studies. Classic machine learning and artificial intelligence techniques cannot provide a full scientific understanding of the inner workings of the underlying models. This raises credibility issues due to the lack of transparency and generalizability. Explainable artificial intelligence is an emerging approach for promoting credibility, accountability, and trust in mission-critical areas such as medicine by combining machine-learning approaches with explanatory techniques that explicitly show what the decision criteria are and why (or how) they have been established. Hence, thinking about how machine learning could benefit from knowledge graphs that combine “common sense” knowledge as well as semantic reasoning and causality models is a potential solution to this problem. In this study, we aimed to leverage explainable artificial intelligence, and propose a proof-of-concept prototype for a knowledge-driven evidence-based recommendation system to improve mental health surveillance. We used concepts from an ontology that we have developed to build and train a question-answering agent using the Google DialogFlow engine. In addition to the question-answering agent, the initial prototype includes knowledge graph generation and recommendation components that leverage third-party graph technology. To showcase the framework functionalities, we here present a prototype design and demonstrate the main features through four use case scenarios motivated by an initiative currently implemented at a children’s hospital in Memphis, Tennessee. Ongoing development of the prototype requires implementing an optimization algorithm of the recommendations, incorporating a privacy layer through a personal health library, and conducting a clinical trial to assess both usability and usefulness of the implementation. This semantic-driven explainable artificial intelligence prototype can enhance health care practitioners’ ability to provide explanations for the decisions they make.

Research Organization:
Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)
Sponsoring Organization:
USDOE Office of Science (SC)
Grant/Contract Number:
AC05-00OR22725
OSTI ID:
1815906
Journal Information:
JMIR medical informatics, Vol. 8, Issue 11; ISSN 2291-9694
Publisher:
JMIR PublicationsCopyright Statement
Country of Publication:
United States
Language:
English

References (13)

Relationship of Childhood Abuse and Household Dysfunction to Many of the Leading Causes of Death in Adults journal May 1998
Screening for Social Determinants of Health Among Children and Families Living in Poverty: A Guide for Clinicians journal May 2016
Managing changes in distributed biomedical ontologies using hierarchical distributed graph transformation journal January 2015
Integrating biomedical research and electronic health records to create knowledge-based biologically meaningful machine-readable embeddings journal July 2019
QAnalysis: a question-answer driven analytic tool on knowledge graphs for leveraging electronic medical records for clinical research journal April 2019
Learning a Health Knowledge Graph from Electronic Medical Records journal July 2017
Geo-clustered chronic affinity: pathways from socio-economic disadvantages to health disparities journal August 2019
Managing Requirement Volatility in an Ontology-Driven Clinical LIMS Using Category Theory journal January 2009
Associations between adverse childhood experiences and health outcomes in adults aged 18–59 years journal February 2019
A Virtual Counseling Application Using Artificial Intelligence for Communication Skills Training in Nursing Education: Development Study journal January 2019
Urban Decay and Pediatric Asthma Prevalence in Memphis, Tennessee: Urban Data Integration for Efficient Population Health Surveillance journal January 2018
Adverse Childhood Experiences Ontology for Mental Health Surveillance, Research, and Evaluation: Advanced Knowledge Representation and Semantic Web Techniques journal January 2019
Medical Question Answering for Clinical Decision Support
  • Goodwin, Travis R.; Harabagiu, Sanda M.
  • CIKM'16: ACM Conference on Information and Knowledge Management, Proceedings of the 25th ACM International on Conference on Information and Knowledge Management https://doi.org/10.1145/2983323.2983819
conference October 2016