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Cytotoxicity and cellular proteome impact of cellulose nanocrystals using simulated digestion and an in vitro small intestinal epithelium cellular model

Journal Article · · NanoImpact
Not Available
Sponsoring Organization:
USDOE
Grant/Contract Number:
AC05-76RL01830
OSTI ID:
1809842
Alternate ID(s):
OSTI ID: 1714363
Journal Information:
NanoImpact, Journal Name: NanoImpact Journal Issue: C Vol. 20; ISSN 2452-0748
Publisher:
ElsevierCopyright Statement
Country of Publication:
Netherlands
Language:
English

References (57)

Safeguarding human and planetary health demands a fertilizer sector transformation journal February 2020
Mass spectrometry-based proteomics for system-level characterization of biological responses to engineered nanomaterials journal June 2018
Characteristics and safety of nano-sized cellulose fibrils journal September 2014
Impacts of chemical modification on the toxicity of diverse nanocellulose materials to developing zebrafish journal April 2016
Development of high throughput, high precision synthesis platforms and characterization methodologies for toxicological studies of nanocellulose journal March 2018
Assessment of Nano Cellulose from Peach Palm Residue as Potential Food Additive: Part II: Preliminary Studies journal December 2014
Proteomic profiling of the differentially expressed proteins by TiO2 nanoparticles in mouse kidney journal December 2010
Cellulose nanocrystals as carriers in medicine and their toxicities: A review journal February 2018
Evaluating mucoadhesion properties of three types of nanocellulose in the gastrointestinal tract in vitro and ex vivo journal April 2019
Fibrillar vs crystalline nanocellulose pulmonary epithelial cell responses: Cytotoxicity or inflammation? journal March 2017
Nanotechnology to the rescue: using nano-enabled approaches in microbiological food safety and quality journal April 2017
A nano-carrier platform for the targeted delivery of nature-inspired antimicrobials using Engineered Water Nanostructures for food safety applications journal February 2019
Properties and stability of oil-in-water emulsions stabilized by microfibrillated cellulose from mangosteen rind journal January 2015
Vegetable nanocellulose in food science: A review journal June 2016
Flexible cellulose nanofibrils as novel pickering stabilizers: The emulsifying property and packing behavior journal March 2019
Antimicrobial poly(lactic acid)/cellulose bionanocomposite for food packaging application: A review journal September 2018
The role of the food matrix and gastrointestinal tract in the assessment of biological properties of ingested engineered nanomaterials (iENMs): State of the science and knowledge gaps journal July 2016
Detection and dissolution of needle-like hydroxyapatite nanomaterials in infant formula journal January 2017
Chronic upper airway inflammation and systemic oxidative stress from nanoparticles in photocopier operators: Mechanistic insights journal January 2017
Development of reference metal and metal oxide engineered nanomaterials for nanotoxicology research using high throughput and precision flame spray synthesis approaches journal April 2018
Development of a standardized food model for studying the impact of food matrix effects on the gastrointestinal fate and toxicity of ingested nanomaterials journal January 2019
Impact of protein-nanoparticle interactions on gastrointestinal fate of ingested nanoparticles: Not just simple protein corona effects journal January 2019
A proteome-wide assessment of the oxidative stress paradigm for metal and metal-oxide nanomaterials in human macrophages journal January 2020
Evaluation of the cytotoxic and cellular proteome impacts of food-grade TiO2 (E171) using simulated gastrointestinal digestions and a tri-culture small intestinal epithelial model journal January 2020
Prediction of protein corona on nanomaterials by machine learning using novel descriptors journal January 2020
Effects of ingested nanocellulose on intestinal microbiota and homeostasis in Wistar Han rats journal April 2020
Nanocellulose in bio-based food packaging applications journal March 2017
Phagocytosis of nano-sized titanium dioxide triggers changes in protein acetylation journal August 2014
Molecular responses of alveolar epithelial A549 cells to chronic exposure to titanium dioxide nanoparticles: A proteomic view journal February 2016
Comparative plasma proteomic studies of pulmonary TiO2 nanoparticle exposure in rats using liquid chromatography tandem mass spectrometry journal January 2016
Characterization of the Interactions between Titanium Dioxide Nanoparticles and Polymethoxyflavones Using Surface-Enhanced Raman Spectroscopy journal December 2016
Physicochemical and Morphological Transformations of Chitosan Nanoparticles across the Gastrointestinal Tract and Cellular Toxicity in an In Vitro Model of the Small Intestinal Epithelium journal December 2019
Dissolution Behavior and Biodurability of Ingested Engineered Nanomaterials in the Gastrointestinal Environment journal July 2018
Reducing Intestinal Digestion and Absorption of Fat Using a Nature-Derived Biopolymer: Interference of Triglyceride Hydrolysis by Nanocellulose journal June 2018
Small-Intestine-Specific Delivery of Antidiabetic Extracts from Withania coagulans Using Polysaccharide-Based Enteric-Coated Nanoparticles journal July 2019
Determination of drug permeability and prediction of drug absorption in Caco-2 monolayers journal August 2007
Is nano safe in foods? Establishing the factors impacting the gastrointestinal fate and toxicity of organic and inorganic food-grade nanoparticles journal November 2017
Banning carbon nanotubes would be scientifically unjustified and damaging to innovation journal March 2020
NanoEHS – defining fundamental science needs: no easy feat when the simple itself is complex journal January 2016
Nanotechnology for sustainable food production: promising opportunities and scientific challenges journal January 2017
Toxicological effects of ingested nanocellulose in in vitro intestinal epithelium and in vivo rat models journal January 2019
Co-exposure to the food additives SiO 2 (E551) or TiO 2 (E171) and the pesticide boscalid increases cytotoxicity and bioavailability of the pesticide in a tri-culture small intestinal epithelium model: potential health implications journal January 2019
Nanomaterial and toxicity: what can proteomics tell us about the nanotoxicology? journal July 2016
Nanocellulose-Based Composites and Bioactive Agents for Food Packaging journal November 2013
Nanomaterials in food and agriculture: An overview on their safety concerns and regulatory issues journal July 2017
Toxicoproteomic identification of TiO 2 nanoparticle-induced protein expression changes in mouse brain journal June 2011
Toxicity of Cellulose Nanocrystals: A Review journal February 2015
In vitro biological responses to nanofibrillated cellulose by human dermal, lung and immune cells: surface chemistry aspect journal January 2017
An integrated methodology for assessing the impact of food matrix and gastrointestinal effects on the biokinetics and cellular toxicity of ingested engineered nanomaterials journal October 2017
Protein corona: implications for nanoparticle interactions with pulmonary cells journal October 2017
Ingested engineered nanomaterials: state of science in nanotoxicity testing and future research needs journal July 2018
Safer-by-design flame-sprayed silicon dioxide nanoparticles: the role of silanol content on ROS generation, surface activity and cytotoxicity journal October 2019
High performance green barriers based on nanocellulose journal November 2014
Comparative Proteomic Analysis of the Molecular Responses of Mouse Macrophages to Titanium Dioxide and Copper Oxide Nanoparticles Unravels Some Toxic Mechanisms for Copper Oxide Nanoparticles in Macrophages journal April 2015
Progress in the characterization and safety evaluation of engineered inorganic nanomaterials in food journal December 2013
Pickering Emulsions Containing Cellulose Microfibers Produced by Mechanical Treatments as Stabilizer in the Food Industry journal January 2019
Engineered Nanomaterials in Food: Implications for Food Safety and Consumer Health journal May 2014