Both ADP-Ribosyl-Binding and Hydrolase Activities of the Alphavirus nsP3 Macrodomain Affect Neurovirulence in Mice
|
journal
|
February 2020 |
Gapped BLAST and PSI-BLAST: a new generation of protein database search programs
|
journal
|
September 1997 |
Expresso: automatic incorporation of structural information in multiple sequence alignments using 3D-Coffee
|
journal
|
July 2006 |
Caffeine-Based Gold(I) N -Heterocyclic Carbenes as Possible Anticancer Agents: Synthesis and Biological Properties
|
journal
|
December 2013 |
Imbalanced Host Response to SARS-CoV-2 Drives Development of COVID-19
|
journal
|
May 2020 |
Defining NADH-Driven Allostery Regulating Apoptosis-Inducing Factor
|
journal
|
December 2016 |
Phaser.MRage : automated molecular replacement
|
journal
|
October 2013 |
PARP14 Controls the Nuclear Accumulation of a Subset of Type I IFN–Inducible Proteins
|
journal
|
March 2018 |
Targeting dePARylation selectively suppresses DNA repair–defective and PARP inhibitor–resistant malignancies
|
journal
|
April 2019 |
A Putative Role of de-Mono-ADP-Ribosylation of STAT1 by the SARS-CoV-2 Nsp3 Protein in the Cytokine Storm Syndrome of COVID-19
|
journal
|
June 2020 |
XRCC1 promotes replication restart, nascent fork degradation and mutagenic DNA repair in BRCA2-deficient cells
|
journal
|
August 2020 |
MUSCLE: multiple sequence alignment with high accuracy and high throughput
|
journal
|
March 2004 |
The use of phosphate bioisosteres in medicinal chemistry and chemical biology
|
journal
|
January 2012 |
Coot model-building tools for molecular graphics
|
journal
|
November 2004 |
The nsp3 Macrodomain Promotes Virulence in Mice with Coronavirus-Induced Encephalitis
|
journal
|
November 2014 |
The Conserved Coronavirus Macrodomain Promotes Virulence and Suppresses the Innate Immune Response during Severe Acute Respiratory Syndrome Coronavirus Infection
|
journal
|
December 2016 |
Viral Macrodomains: Unique Mediators of Viral Replication and Pathogenesis
|
journal
|
July 2018 |
Molecular Basis for ADP-Ribose Binding to the Mac1 Domain of SARS-CoV-2 nsp3
|
journal
|
June 2020 |
Anchored plasticity opens doors for selective inhibitor design in nitric oxide synthase
|
journal
|
October 2008 |
The coronavirus macrodomain is required to prevent PARP-mediated inhibition of virus replication and enhancement of IFN expression
|
journal
|
May 2019 |
Clinical Characteristics of Coronavirus Disease 2019 in China
|
journal
|
April 2020 |
The ARTT motif and a unified structural understanding of substrate recognition in ADP-ribosylating bacterial toxins and eukaryotic ADP-ribosyltransferases
|
journal
|
January 2001 |
Synthesis and biological evaluation of novel xanthine derivatives as potential apoptotic antitumor agents
|
journal
|
August 2019 |
Deep transcriptome-sequencing and proteome analysis of the hydrothermal vent annelid Alvinella pompejana identifies the CvP-bias as a robust measure of eukaryotic thermostability
|
journal
|
January 2013 |
Selective small molecule PARG inhibitor causes replication fork stalling and cancer cell death
|
journal
|
December 2019 |
PARP9 and PARP14 cross-regulate macrophage activation via STAT1 ADP-ribosylation
|
journal
|
October 2016 |
A family of macrodomain proteins reverses cellular mono-ADP-ribosylation
|
journal
|
March 2013 |
XDS
|
journal
|
January 2010 |
Structure of mammalian poly(ADP-ribose) glycohydrolase reveals a flexible tyrosine clasp as a substrate-binding element
|
journal
|
May 2012 |
MEGA X: Molecular Evolutionary Genetics Analysis across Computing Platforms
|
journal
|
May 2018 |
Identifying SARS-CoV-2 related coronaviruses in Malayan pangolins
|
journal
|
March 2020 |
Synthesis of Dimeric ADP-Ribose and Its Structure with Human Poly(ADP-ribose) Glycohydrolase
|
journal
|
March 2015 |
Cancer patients in SARS-CoV-2 infection: a nationwide analysis in China
|
journal
|
March 2020 |
An Evolutionary Trace Method Defines Binding Surfaces Common to Protein Families
|
journal
|
March 1996 |
Macromolecular structure determination using X-rays, neutrons and electrons: recent developments in Phenix
|
journal
|
October 2019 |
Polder maps: improving OMIT maps by excluding bulk solvent
|
journal
|
February 2017 |
Structural, Biophysical, and Biochemical Elucidation of the SARS-CoV-2 Nonstructural Protein 3 Macro Domain
|
journal
|
September 2020 |
PyETV: a PyMOL evolutionary trace viewer to analyze functional site predictions in protein complexes
|
journal
|
October 2010 |
ADP-ribosylhydrolase activity of Chikungunya virus macrodomain is critical for virus replication and virulence
|
journal
|
January 2017 |
Crystal structures of SARS-CoV-2 ADP-ribose phosphatase: from the apo form to ligand complexes
|
journal
|
July 2020 |
A Family of Evolution–Entropy Hybrid Methods for Ranking Protein Residues by Importance
|
journal
|
March 2004 |
Targeting Allostery with Avatars to Design Inhibitors Assessed by Cell Activity: Dissecting MRE11 Endo- and Exonuclease Activities
|
book
|
January 2018 |
electronic Ligand Builder and Optimization Workbench ( eLBOW ): a tool for ligand coordinate and restraint generation
|
journal
|
September 2009 |
Collaboration gets the most out of software
|
journal
|
September 2013 |
T-coffee: a novel method for fast and accurate multiple sequence alignment 1 1Edited by J. Thornton
|
journal
|
September 2000 |
Update on therapeutic approaches and emerging therapies for SARS-CoV-2 virus
|
journal
|
September 2020 |
UCSF Chimera?A visualization system for exploratory research and analysis
|
journal
|
January 2004 |
PARG has a robust endo-glycohydrolase activity that releases protein-free poly(ADP-ribose) chains
|
journal
|
June 2020 |
NCBI reference sequences (RefSeq): a curated non-redundant sequence database of genomes, transcripts and proteins
|
journal
|
January 2007 |
(ADP-ribosyl)hydrolases: structure, function, and biology
|
journal
|
February 2020 |
Macrodomains: Structure, Function, Evolution, and Catalytic Activities
|
journal
|
June 2016 |
Viral macrodomains: a structural and evolutionary assessment of the pharmacological potential
|
journal
|
November 2020 |
The Stanford Automated Mounter: pushing the limits of sample exchange at the SSRL macromolecular crystallography beamlines
|
journal
|
February 2016 |
Microscale thermophoresis quantifies biomolecular interactions under previously challenging conditions
|
journal
|
March 2013 |
DNA Double-Strand Break Repair Pathway Choice Is Directed by Distinct MRE11 Nuclease Activities
|
journal
|
January 2014 |
Superoxide Dismutase from the Eukaryotic Thermophile Alvinella pompejana: Structures, Stability, Mechanism, and Insights into Amyotrophic Lateral Sclerosis
|
journal
|
February 2009 |
Drug Discovery Strategies for SARS-CoV-2
|
journal
|
July 2020 |
PARP and PARG inhibitors in cancer treatment
|
journal
|
February 2020 |
The structure and catalytic mechanism of a poly(ADP-ribose) glycohydrolase
|
journal
|
September 2011 |
New paradigm for macromolecular crystallography experiments at SSRL: automated crystal screening and remote data collection
|
journal
|
November 2008 |
AUGUSTUS: a web server for gene prediction in eukaryotes that allows user-defined constraints
|
journal
|
July 2005 |
Molecular Evolutionary Genetics Analysis (MEGA) for macOS
|
journal
|
January 2020 |
UniRef clusters: a comprehensive and scalable alternative for improving sequence similarity searches
|
journal
|
November 2014 |
The MRE11–RAD50–NBS1 Complex Conducts the Orchestration of Damage Signaling and Outcomes to Stress in DNA Replication and Repair
|
journal
|
June 2018 |
The reactivity of anti-peptide antibodies is a function of the atomic mobility of sites in a protein
|
journal
|
November 1984 |
Genomic evidence for reinfection with SARS-CoV-2: a case study
|
journal
|
January 2021 |
In vitro screening of a FDA approved chemical library reveals potential inhibitors of SARS-CoV-2 replication
|
journal
|
August 2020 |
Structures of the Human Poly (ADP-Ribose) Glycohydrolase Catalytic Domain Confirm Catalytic Mechanism and Explain Inhibition by ADP-HPD Derivatives
|
journal
|
December 2012 |
Poly(ADP-Ribose) (PAR) Binding to Apoptosis-Inducing Factor Is Critical for PAR Polymerase-1-Dependent Cell Death (Parthanatos)
|
journal
|
April 2011 |
Sequence homology between human PARP14 and the SARS-CoV-2 ADP ribose 1’-phosphatase
|
journal
|
August 2020 |
Overview of the CCP 4 suite and current developments
|
journal
|
March 2011 |
Structural basis for allosteric PARP-1 retention on DNA breaks
|
journal
|
April 2020 |
Cytokine release syndrome in severe COVID-19: interleukin-6 receptor antagonist tocilizumab may be the key to reduce mortality
|
journal
|
May 2020 |
PARP9-DTX3L ubiquitin ligase targets host histone H2BJ and viral 3C protease to enhance interferon signaling and control viral infection
|
journal
|
December 2015 |
A pneumonia outbreak associated with a new coronavirus of probable bat origin
|
journal
|
February 2020 |