Genomic and Phenotypic Characterization of Chloracidobacterium Isolates Provides Evidence for Multiple Species

Saini, Mohit Kumar; Sebastian, Aswathy; Shirotori, Yoshiki; Soulier, Nathan T.; Garcia Costas, Amaya M.; Drautz-Moses, Daniela I.; Schuster, Stephan C.; Albert, Istvan; Haruta, Shin; Hanada, Satoshi; Thiel, Vera; Tank, Marcus; Bryant, Donald A.

doi:10.3389/fmicb.2021.704168

Genomic and Phenotypic Characterization of Chloracidobacterium Isolates Provides Evidence for Multiple Species

Journal Article · Thu Jun 17 00:00:00 EDT 2021 · Frontiers in Microbiology

DOI:https://doi.org/10.3389/fmicb.2021.704168· OSTI ID:1797509

Saini, Mohit Kumar; Sebastian, Aswathy; Shirotori, Yoshiki; Soulier, Nathan T.; Garcia Costas, Amaya M.; Drautz-Moses, Daniela I.; Schuster, Stephan C.; Albert, Istvan; Haruta, Shin; Hanada, Satoshi; Thiel, Vera; Tank, Marcus; Bryant, Donald A.

Chloracidobacterium is the first and until now the sole genus in the phylum Acidobacteriota (formerly Acidobacteria ) whose members perform chlorophyll-dependent phototrophy (i.e., chlorophototrophy). An axenic isolate of Chloracidobacterium thermophilum (strain B ^T ) was previously obtained by using the inferred genome sequence from an enrichment culture and diel metatranscriptomic profiling analyses in situ to direct adjustments to the growth medium and incubation conditions, and thereby a defined growth medium for Chloracidobacterium thermophilum was developed. These advances allowed eight additional strains of Chloracidobacterium spp. to be isolated from microbial mat samples collected from Mushroom Spring, Yellowstone National Park, United States, at temperatures of 41, 52, and 60°C; an axenic strain was also isolated from Rupite hot spring in Bulgaria. All isolates are obligately photoheterotrophic, microaerophilic, non-motile, thermophilic, rod-shaped bacteria. Chloracidobacterium spp. synthesize multiple types of (bacterio-)chlorophylls and have type-1 reaction centers like those of green sulfur bacteria. Light harvesting is accomplished by the bacteriochlorophyll a -binding, Fenna-Matthews-Olson protein and chlorosomes containing bacteriochlorophyll c . Their genomes are approximately 3.7 Mbp in size and comprise two circular chromosomes with sizes of approximately 2.7 Mbp and 1.0 Mbp. Comparative genomic studies and phenotypic properties indicate that the nine isolates represent three species within the genus Chloracidobacterium . In addition to C. thermophilum , the microbial mats at Mushroom Spring contain a second species, tentatively named Chloracidobacterium aggregatum , which grows as aggregates in liquid cultures. The Bulgarian isolate, tentatively named Chloracidobacterium validum , will be proposed as the type species of the genus, Chloracidobacterium. Additionally, Chloracidobacterium will be proposed as the type genus of a new family, Chloracidobacteriaceae , within the order Blastocatellales , the class Blastocatellia , and the phylum Acidobacteriota.

View Journal Article

Research Organization:: Pennsylvania State Univ., University Park, PA (United States)

Sponsoring Organization:: National Aeronautics and Space Administration (NASA); USDOE; USDOE Office of Science (SC)

Grant/Contract Number:: FG02-94ER20137

OSTI ID:: 1797509

Alternate ID(s):: OSTI ID: 1850068

Journal Information:: Frontiers in Microbiology, Journal Name: Frontiers in Microbiology Vol. 12; ISSN 1664-302X

Publisher:: Frontiers Media SACopyright Statement

Country of Publication:: Switzerland

Language:: English

References (66)

Bergey's Manual of Systematics of Archaea and Bacteria Whitman, William B.; DeVos, Paul; Dedysh, Svetlana Wiley https://doi.org/10.1002/9781118960608	reference-book	September 2015
Diversity and abundance ofBacteria andArchaea in the Bor Khlueng Hot Spring in Thailand Kanokratana, Pattanop; Chanapan, Supavadee; Pootanakit, Kusol Journal of Basic Microbiology, Vol. 44, Issue 6 https://doi.org/10.1002/jobm.200410388	journal	December 2004
When should a DDH experiment be mandatory in microbial taxonomy? Meier-Kolthoff, Jan P.; Göker, Markus; Spröer, Cathrin Archives of Microbiology, Vol. 195, Issue 6 https://doi.org/10.1007/s00203-013-0888-4	journal	April 2013
Quinones in chlorosomes of green sulfur bacteria and their role in the redox-dependent fluorescence studied in chlorosome-like bacteriochlorophyll c aggregates Frigaard, N. -U.; Takaichi, Shinichi; Hirota, Masamitsu Archives of Microbiology, Vol. 167, Issue 6 https://doi.org/10.1007/s002030050453	journal	May 1997
Phototrophic Phylotypes Dominate Mesothermal Microbial Mats Associated with Hot Springs in Yellowstone National Park Ross, Kimberly A.; Feazel, Leah M.; Robertson, Charles E. Microbial Ecology, Vol. 64, Issue 1 https://doi.org/10.1007/s00248-012-0012-3	journal	February 2012
Bacterial community composition in thermophilic microbial mats from five hot springs in central Tibet Lau, Maggie C. Y.; Aitchison, Jonathan C.; Pointing, Stephen B. Extremophiles, Vol. 13, Issue 1 https://doi.org/10.1007/s00792-008-0205-3	journal	November 2008
High diversity of thermophilic cyanobacteria in Rupite hot spring identified by microscopy, cultivation, single-cell PCR and amplicon sequencing Strunecký, Otakar; Kopejtka, Karel; Goecke, Franz Extremophiles, Vol. 23, Issue 1 https://doi.org/10.1007/s00792-018-1058-z	journal	October 2018
Characterization of the FMO protein from the aerobic chlorophototroph, Candidatus Chloracidobacterium thermophilum Tsukatani, Yusuke; Wen, Jianzhong; Blankenship, Robert E. Photosynthesis Research, Vol. 104, Issue 2-3 https://doi.org/10.1007/s11120-009-9517-0	journal	January 2010
15N photo-CIDNP MAS NMR analysis of reaction centers of Chloracidobacterium thermophilum Zill, Jeremias C.; He, Zhihui; Tank, Marcus Photosynthesis Research, Vol. 137, Issue 2 https://doi.org/10.1007/s11120-018-0504-1	journal	March 2018
Reaction centers of the thermophilic microaerophile, Chloracidobacterium thermophilum (Acidobacteria) I: biochemical and biophysical characterization He, Zhihui; Ferlez, Bryan; Kurashov, Vasily Photosynthesis Research, Vol. 142, Issue 1 https://doi.org/10.1007/s11120-019-00650-9	journal	June 2019
Structural model and spectroscopic characteristics of the FMO antenna protein from the aerobic chlorophototroph, Candidatus Chloracidobacterium thermophilum Wen, Jianzhong; Tsukatani, Yusuke; Cui, Weidong Biochimica et Biophysica Acta (BBA) - Bioenergetics, Vol. 1807, Issue 1 https://doi.org/10.1016/j.bbabio.2010.09.008	journal	January 2011
Blastocatella fastidiosa gen. nov., sp. nov., isolated from semiarid savanna soil – The first described species of Acidobacteria subdivision 4 Foesel, Bärbel U.; Rohde, Manfred; Overmann, Jörg Systematic and Applied Microbiology, Vol. 36, Issue 2 https://doi.org/10.1016/j.syapm.2012.11.002	journal	March 2013
Population level functional diversity in a microbial community revealed by comparative genomic and metagenomic analyses Bhaya, Devaki; Grossman, Arthur R.; Steunou, Anne-Soisig The ISME Journal, Vol. 1, Issue 8 https://doi.org/10.1038/ismej.2007.46	journal	October 2007
Metatranscriptomic analyses of chlorophototrophs of a hot-spring microbial mat Liu, Zhenfeng; Klatt, Christian G.; Wood, Jason M. The ISME Journal, Vol. 5, Issue 8 https://doi.org/10.1038/ismej.2011.37	journal	June 2011
Community ecology of hot spring cyanobacterial mats: predominant populations and their functional potential Klatt, Christian G.; Wood, Jason M.; Rusch, Douglas B. The ISME Journal, Vol. 5, Issue 8 https://doi.org/10.1038/ismej.2011.73	journal	June 2011
‘Candidatus Thermochlorobacter aerophilum:’ an aerobic chlorophotoheterotrophic member of the phylum Chlorobi defined by metagenomics and metatranscriptomics Liu, Zhenfeng; Klatt, Christian G.; Ludwig, Marcus The ISME Journal, Vol. 6, Issue 10 https://doi.org/10.1038/ismej.2012.24	journal	March 2012
Nonhybrid, finished microbial genome assemblies from long-read SMRT sequencing data Chin, Chen-Shan; Alexander, David H.; Marks, Patrick Nature Methods, Vol. 10, Issue 6 https://doi.org/10.1038/nmeth.2474	journal	May 2013
TYGS is an automated high-throughput platform for state-of-the-art genome-based taxonomy Meier-Kolthoff, Jan P.; Göker, Markus Nature Communications, Vol. 10, Issue 1 https://doi.org/10.1038/s41467-019-10210-3	journal	May 2019
RASTtk: A modular and extensible implementation of the RAST algorithm for building custom annotation pipelines and annotating batches of genomes Brettin, Thomas; Davis, James J.; Disz, Terry Scientific Reports, Vol. 5, Issue 1 https://doi.org/10.1038/srep08365	journal	February 2015
BPGA- an ultra-fast pan-genome analysis pipeline Chaudhari, Narendrakumar M.; Gupta, Vinod Kumar; Dutta, Chitra Scientific Reports, Vol. 6, Issue 1 https://doi.org/10.1038/srep24373	journal	April 2016
Two-dimensional ⁶⁷ Zn HYSCORE spectroscopy reveals that a Zn-bacteriochlorophyll a _P ′ dimer is the primary donor (P ₈₄₀ ) in the type-1 reaction centers of Chloracidobacterium thermophilum Charles, Philip; Kalendra, Vidmantas; He, Zhihui Physical Chemistry Chemical Physics, Vol. 22, Issue 11 https://doi.org/10.1039/c9cp06556c	journal	January 2020
Shifting the genomic gold standard for the prokaryotic species definition Richter, Michael; Rosselló-Móra, Ramon Proceedings of the National Academy of Sciences, Vol. 106, Issue 45 https://doi.org/10.1073/pnas.0906412106	journal	October 2009
Isolation and Characterization of Homodimeric Type-I Reaction Center Complex from Candidatus Chloracidobacterium thermophilum, an Aerobic Chlorophototroph Tsukatani, Yusuke; Romberger, Steven P.; Golbeck, John H. Journal of Biological Chemistry, Vol. 287, Issue 8 https://doi.org/10.1074/jbc.M111.323329	journal	December 2011
Estimating Phylogenetic Trees from Distance Matrices Farris, James S. The American Naturalist, Vol. 106, Issue 951 https://doi.org/10.1086/282802	journal	September 1972
How Many Bootstrap Replicates Are Necessary? Pattengale, Nicholas D.; Alipour, Masoud; Bininda-Emonds, Olaf R. P. Journal of Computational Biology, Vol. 17, Issue 3 https://doi.org/10.1089/cmb.2009.0179	journal	March 2010
RAxML version 8: a tool for phylogenetic analysis and post-analysis of large phylogenies Stamatakis, Alexandros Bioinformatics, Vol. 30, Issue 9 https://doi.org/10.1093/bioinformatics/btu033	journal	January 2014
JSpeciesWS: a web server for prokaryotic species circumscription based on pairwise genome comparison Richter, Michael; Rosselló-Móra, Ramon; Oliver Glöckner, Frank Bioinformatics, Vol. 32, Issue 6 https://doi.org/10.1093/bioinformatics/btv681	journal	November 2015
PhyD3: a phylogenetic tree viewer with extended phyloXML support for functional genomics data visualization Kreft, Łukasz; Botzki, Alexander; Coppens, Frederik Bioinformatics, Vol. 33, Issue 18 https://doi.org/10.1093/bioinformatics/btx324	journal	May 2017
FastME 2.0: A Comprehensive, Accurate, and Fast Distance-Based Phylogeny Inference Program: Table 1. Lefort, Vincent; Desper, Richard; Gascuel, Olivier Molecular Biology and Evolution, Vol. 32, Issue 10 https://doi.org/10.1093/molbev/msv150	journal	June 2015
MUSCLE: multiple sequence alignment with high accuracy and high throughput Edgar, R. C. Nucleic Acids Research, Vol. 32, Issue 5, p. 1792-1797 https://doi.org/10.1093/nar/gkh340	journal	March 2004
The SEED and the Rapid Annotation of microbial genomes using Subsystems Technology (RAST) Overbeek, Ross; Olson, Robert; Pusch, Gordon D. Nucleic Acids Research, Vol. 42, Issue D1 https://doi.org/10.1093/nar/gkt1226	journal	November 2013
Chloracidobacterium thermophilum gen. nov., sp. nov.: an anoxygenic microaerophilic chlorophotoheterotrophic acidobacterium Tank, M.; Bryant, D. A. INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY, Vol. 65, Issue Pt 5 https://doi.org/10.1099/ijs.0.000113	journal	February 2015
Pyrinomonas methylaliphatogenes gen. nov., sp. nov., a novel group 4 thermophilic member of the phylum Acidobacteria from geothermal soils Crowe, M. A.; Power, J. F.; Morgan, X. C. INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY, Vol. 64, Issue Pt 1 https://doi.org/10.1099/ijs.0.055079-0	journal	September 2013
Streptobacillus notomytis sp. nov., isolated from a spinifex hopping mouse (Notomys alexis Thomas, 1922), and emended description of Streptobacillus Levaditi et al. 1925, Eisenberg et al. 2015 emend. Eisenberg, Tobias; Glaeser, Stefanie P.; Ewers, Christa International Journal of Systematic and Evolutionary Microbiology, Vol. 65, Issue Pt_12 https://doi.org/10.1099/ijsem.0.000654	journal	December 2015
Proposal of the suffix –ota to denote phyla. Addendum to ‘Proposal to include the rank of phylum in the International Code of Nomenclature of Prokaryotes’ Whitman, William B.; Oren, Aharon; Chuvochina, Maria International Journal of Systematic and Evolutionary Microbiology, Vol. 68, Issue 3 https://doi.org/10.1099/ijsem.0.002593	journal	March 2018
Refining the taxonomic structure of the phylum Acidobacteria Dedysh, Svetlana N.; Yilmaz, Pelin International Journal of Systematic and Evolutionary Microbiology, Vol. 68, Issue 12 https://doi.org/10.1099/ijsem.0.003062	journal	December 2018
Granulicella sibirica sp. nov., a psychrotolerant acidobacterium isolated from an organic soil layer in forested tundra, West Siberia Oshkin, Igor Y.; Kulichevskaya, Irina S.; Rijpstra, W. Irene C. International Journal of Systematic and Evolutionary Microbiology, Vol. 69, Issue 4 https://doi.org/10.1099/ijsem.0.003290	journal	April 2019
Caldichromatium japonicum gen. nov., sp. nov., a novel thermophilic phototrophic purple sulphur bacterium of the Chromatiaceae isolated from Nakabusa hot springs, Japan Saini, Mohit Kumar; ChihChe, Weng; Soulier, Nathan International Journal of Systematic and Evolutionary Microbiology, Vol. 70, Issue 11 https://doi.org/10.1099/ijsem.0.004465	journal	November 2020
CheckM: assessing the quality of microbial genomes recovered from isolates, single cells, and metagenomes Parks, Donovan H.; Imelfort, Michael; Skennerton, Connor T. Genome Research, Vol. 25, Issue 7 https://doi.org/10.1101/gr.186072.114	journal	May 2015
Canu: scalable and accurate long-read assembly via adaptive k -mer weighting and repeat separation Koren, Sergey; Walenz, Brian P.; Berlin, Konstantin Genome Research, Vol. 27, Issue 5 https://doi.org/10.1101/gr.215087.116	journal	March 2017
Mauve: Multiple Alignment of Conserved Genomic Sequence With Rearrangements Darling, A. C. E. Genome Research, Vol. 14, Issue 7 https://doi.org/10.1101/gr.2289704	journal	June 2004
Phylogeographic History of the land Snail Candidula Unifasciata (Helicellinae, Stylommatophora): Fragmentation, Corridor Migration, and Secondary Contact Pfenninger, Markus; Posada, David Evolution, Vol. 56, Issue 9 https://doi.org/10.1111/j.0014-3820.2002.tb00191.x	journal	September 2002
An empirical test of the midpoint rooting method: A TEST FOR THE MIDPOINT ROOTING METHOD Hess, Pablo N.; De Moraes Russo, Claudia A. Biological Journal of the Linnean Society, Vol. 92, Issue 4 https://doi.org/10.1111/j.1095-8312.2007.00864.x	journal	December 2007
TNT, a free program for phylogenetic analysis Goloboff, Pablo A.; Farris, James S.; Nixon, Kevin C. Cladistics, Vol. 24, Issue 5 https://doi.org/10.1111/j.1096-0031.2008.00217.x	journal	October 2008
Application of tetranucleotide frequencies for the assignment of genomic fragments Teeling, Hanno; Meyerdierks, Anke; Bauer, Margarete Environmental Microbiology, Vol. 6, Issue 9 https://doi.org/10.1111/j.1462-2920.2004.00624.x	journal	September 2004
Complete genome of Candidatus Chloracidobacterium thermophilum, a chlorophyll-based photoheterotroph belonging to the phylum Acidobacteria: Candidatus Chloracidobacterium thermophilum genome Garcia Costas, Amaya M.; Liu, Zhenfeng; Tomsho, Lynn P. Environmental Microbiology, Vol. 14, Issue 1 https://doi.org/10.1111/j.1462-2920.2011.02592.x	journal	September 2011
Highly diverse community structure in a remote central Tibetan geothermal spring does not display monotonic variation to thermal stress: Microbial diversity and thermal stress Yim, Lau Chui; Hongmei, Jing; Aitchison, Jonathan C. FEMS Microbiology Ecology, Vol. 57, Issue 1 https://doi.org/10.1111/j.1574-6941.2006.00104.x	journal	July 2006
Detection and in situ identification of representatives of a widely distributed new bacterial phylum Ludwig, Wolfgang; Bauer, Stephan H.; Bauer, Marc FEMS Microbiology Letters, Vol. 153, Issue 1 https://doi.org/10.1111/j.1574-6968.1997.tb10480.x	journal	August 1997
Candidatus Chloracidobacterium thermophilum: An Aerobic Phototrophic Acidobacterium Bryant, D. A.; Costas, A. M. G.; Maresca, J. A. Science, Vol. 317, Issue 5837 https://doi.org/10.1126/science.1143236	journal	July 2007
Bar-Coded Pyrosequencing Reveals Shared Bacterial Community Properties along the Temperature Gradients of Two Alkaline Hot Springs in Yellowstone National Park Miller, S. R.; Strong, A. L.; Jones, K. L. Applied and Environmental Microbiology, Vol. 75, Issue 13 https://doi.org/10.1128/AEM.02792-08	journal	May 2009
Ultrastructural Analysis and Identification of Envelope Proteins of "Candidatus Chloracidobacterium thermophilum" Chlorosomes Garcia Costas, A. M.; Tsukatani, Y.; Romberger, S. P. Journal of Bacteriology, Vol. 193, Issue 23 https://doi.org/10.1128/JB.06124-11	journal	September 2011
Identification of the Bacteriochlorophylls, Carotenoids, Quinones, Lipids, and Hopanoids of "Candidatus Chloracidobacterium thermophilum" Garcia Costas, A. M.; Tsukatani, Y.; Rijpstra, W. I. C. Journal of Bacteriology, Vol. 194, Issue 5 https://doi.org/10.1128/JB.06421-11	journal	December 2011
Draft Genome Sequence of the Deinococcus-Thermus Bacterium Meiothermus ruber Strain A Thiel, Vera; Tomsho, Lynn P.; Burhans, Richard Genome Announcements, Vol. 3, Issue 2 https://doi.org/10.1128/genomeA.00202-15	journal	March 2015
Draft Genome Sequence of Anoxybacillus ayderensis Strain MT-Cab ( Firmicutes ) Thiel, Vera; Tank, Marcus; Tomsho, Lynn P. Genome Announcements, Vol. 5, Issue 26 https://doi.org/10.1128/genomeA.00547-17	journal	June 2017
Draft Genome Sequence of Chloracidobacterium sp. CP2_5A, a Phototrophic Member of the Phylum Acidobacteria Recovered from a Japanese Hot Spring Ward, Lewis M.; McGlynn, Shawn E.; Fischer, Woodward W. Genome Announcements, Vol. 5, Issue 40 https://doi.org/10.1128/genomeA.00821-17	journal	October 2017
Draft Genome Sequence of the Photoheterotrophic Chloracidobacterium thermophilum Strain OC1 Found in a Mat at Ojo Caliente Hallenbeck, Patrick C.; Grogger, Melanie; Mraz, Megan Genome Announcements, Vol. 4, Issue 1 https://doi.org/10.1128/genomeA.01570-15	journal	February 2016
Diversity of Chlorophototrophic Bacteria Revealed in the Omics Era Thiel, Vera; Tank, Marcus; Bryant, Donald A. Annual Review of Plant Biology, Vol. 69, Issue 1 https://doi.org/10.1146/annurev-arplant-042817-040500	journal	April 2018
Genome sequence-based species delimitation with confidence intervals and improved distance functions Meier-Kolthoff, Jan P.; Auch, Alexander F.; Klenk, Hans-Peter BMC Bioinformatics, Vol. 14, Issue 1 https://doi.org/10.1186/1471-2105-14-60	journal	January 2013
BLAST Ring Image Generator (BRIG): simple prokaryote genome comparisons Alikhan, Nabil-Fareed; Petty, Nicola K.; Ben Zakour, Nouri L. BMC Genomics, Vol. 12, Issue 1 https://doi.org/10.1186/1471-2164-12-402	journal	August 2011
The RAST Server: Rapid Annotations using Subsystems Technology Aziz, Ramy K.; Bartels, Daniela; Best, Aaron A. BMC Genomics, Vol. 9, Issue 1, Article No. 75 https://doi.org/10.1186/1471-2164-9-75	journal	January 2008
Complete genome sequence of DSM 30083T, the type strain (U5/41T) of Escherichia coli, and a proposal for delineating subspecies in microbial taxonomy Meier-Kolthoff, Jan P.; Hahnke, Richard L.; Petersen, Jörn Standards in Genomic Sciences, Vol. 9, Issue 1 https://doi.org/10.1186/1944-3277-9-2	journal	January 2014
Circlator: automated circularization of genome assemblies using long sequencing reads Hunt, Martin; Silva, Nishadi De; Otto, Thomas D. Genome Biology, Vol. 16, Issue 1 https://doi.org/10.1186/s13059-015-0849-0	journal	December 2015
Genomic diversity within the haloalkaliphilic genus Thioalkalivibrio Ahn, Anne-Catherine; Meier-Kolthoff, Jan P.; Overmars, Lex PLOS ONE, Vol. 12, Issue 3 https://doi.org/10.1371/journal.pone.0173517	journal	March 2017
Bacteriochlorophyll f: properties of chlorosomes containing the “forbidden chlorophyll” Vogl, Kajetan; Tank, Marcus; Orf, Gregory S. Frontiers in Microbiology, Vol. 3 https://doi.org/10.3389/fmicb.2012.00298	journal	August 2012
Nutrient requirements and growth physiology of the photoheterotrophic Acidobacterium, Chloracidobacterium thermophilum Tank, Marcus; Bryant, Donald A. Frontiers in Microbiology, Vol. 06 https://doi.org/10.3389/fmicb.2015.00226	journal	March 2015
Digital DNA-DNA hybridization for microbial species delineation by means of genome-to-genome sequence comparison Auch, Alexander F.; von Jan, Mathias; Klenk, Hans-Peter Standards in Genomic Sciences, Vol. 2, Issue 1 https://doi.org/10.4056/sigs.531120	journal	January 2010

Similar Records

Light Energy Transduction in Green Sulfur Bacteria

Technical Report · Mon Mar 27 00:00:00 EDT 2023 · OSTI ID:1781749

Nutrient requirements and growth physiology of the photoheterotrophic Acidobacterium, Chloracidobacterium thermophilum

Journal Article · Thu Mar 26 20:00:00 EDT 2015 · Frontiers in Microbiology · OSTI ID:1194070

Related Subjects

59 BASIC BIOLOGICAL SCIENCES
acidobacteriota
chloracidobacterium
chlorophototrophy
genome
microbiology
thermophile

Genomic and Phenotypic Characterization of Chloracidobacterium Isolates Provides Evidence for Multiple Species

Citation Formats

References (66)

Similar Records

Related Subjects