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Title: The Autocatalytic Cleavage Domain Is Not Required for the Activity of ScpC, a Virulence Protease fro

Journal Article · · Biochemistry-US
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Research Organization:
Argonne National Lab. (ANL), Argonne, IL (United States). Advanced Photon Source (APS)
Sponsoring Organization:
DOE - Office Of Science; National Institutes of Health (NIH)
OSTI ID:
1783893
Journal Information:
Biochemistry-US, Vol. 60, Issue (19)
Country of Publication:
United States
Language:
ENGLISH

References (21)

Practice Guidelines for the Diagnosis and Management of Skin and Soft-Tissue Infections journal November 2005
Disease Manifestations and Pathogenic Mechanisms of Group A Streptococcus journal April 2014
Uncovering the mysteries of invasive streptococcal diseases journal April 2005
The global burden of group A streptococcal diseases journal November 2005
Epidemiology of Invasive Group A Streptococcal Infections in the United States, 2005–2012 journal April 2016
Whole genome sequencing reveals extensive community-level transmission of group A Streptococcus in remote communities journal February 2016
Extensive Diversity of Streptococcus pyogenes in a Remote Human Population Reflects Global-Scale Transmission Rather than Localised Diversification journal September 2013
A Chemokine-Degrading Extracellular Protease Made by Group A Streptococcus Alters Pathogenesis by Enhancing Evasion of the Innate Immune Response journal January 2008
Identification of novel immunoreactive proteins of Streptococcus zooepidemicus with potential as vaccine components journal August 2013
Strategic development of the conserved region of the M protein and other candidates as vaccines to prevent infection with group A streptococci journal July 2015
The quest for GAS vaccine journal October 2015
A Synthetic M Protein Peptide Synergizes with a CXC Chemokine Protease To Induce Vaccine-Mediated Protection against Virulent Streptococcal Pyoderma and Bacteremia journal May 2015
Combinatorial Synthetic Peptide Vaccine Strategy Protects against Hypervirulent CovR/S Mutant Streptococci journal March 2016
Streptococcus pyogenes SpyCEP: a chemokine-inactivating protease with unique structural and biochemical features journal August 2010
A streptococcal protease that degrades CXC chemokines and impairs bacterial clearance from infected tissues journal September 2006
Effect of a bacterial pheromone peptide on host chemokine degradation in group A streptococcal necrotising soft-tissue infections journal February 2004
Chemokine-cleaving Streptococcus pyogenes protease SpyCEP is necessary and sufficient for bacterial dissemination within soft tissues and the respiratory tract: SpyCEP and S. pyogenes dissemination journal February 2010
The IL-8 Protease SpyCEP/ScpC of Group A Streptococcus Promotes Resistance to Neutrophil Killing journal August 2008
Multi High-Throughput Approach for Highly Selective Identification of Vaccine Candidates: the Group A Streptococcus Case journal June 2012
Structure of ScpC, a virulence protease from Streptococcus pyogenes, reveals the functional domains and maturation mechanism journal September 2018
The C X C Chemokine-degrading Protease SpyCep of Streptococcus pyogenes Promotes Its Uptake into Endothelial Cells journal June 2010

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