Skip to main content
U.S. Department of Energy
Office of Scientific and Technical Information

How Cooperative Engagement Programs Strengthen Sequencing Capabilities for Biosurveillance and Outbreak Response

Journal Article · · Frontiers in Public Health

The threat of emerging and re-emerging infectious diseases continues to be a challenge to public and global health security. Cooperative biological engagement programs act to build partnerships and collaborations between scientists and health professionals to strengthen capabilities in biosurveillance. Biosurveillance is the systematic process of detecting, reporting, and responding to especially dangerous pathogens and pathogens of pandemic potential before they become outbreaks, epidemics, and pandemics. One important tool in biosurveillance is next generation sequencing. Expensive sequencing machines, reagents, and supplies make it difficult for countries to adopt this technology. Cooperative engagement programs help by providing funding for technical assistance to strengthen sequencing capabilities. Through workshops and training, countries are able to learn sequencing and bioinformatics, and implement these tools in their biosurveillance programs. Cooperative programs have an important role in building and sustaining collaborations among institutions and countries. One of the most important pieces in fostering these collaborations is trust. Trust provides the confidence that a successful collaboration will benefit all parties involved. With sequencing, this enables the sharing of pathogen samples and sequences. Obtaining global sequencing data helps to identify unknown etiological agents, track pathogen evolution and infer transmission networks throughout the duration of a pandemic. Having sequencing technology in place for biosurveillance generates the capacity to provide real-time data to understand and respond to pandemics. We highlight the need for these programs to continue to strengthen sequencing in biosurveillance. By working together to strengthen sequencing capabilities, trust can be formed, benefitting global health in the face of biological threats.

Research Organization:
Los Alamos National Laboratory (LANL), Los Alamos, NM (United States)
Sponsoring Organization:
USDOE
Grant/Contract Number:
89233218CNA000001
OSTI ID:
1783542
Report Number(s):
LA-UR--21-21158
Journal Information:
Frontiers in Public Health, Journal Name: Frontiers in Public Health Vol. 9; ISSN 2296-2565
Publisher:
Frontiers Research FoundationCopyright Statement
Country of Publication:
United States
Language:
English

References (32)

Learning from the Past: Possible Urgent Prevention and Treatment Options for Severe Acute Respiratory Infections Caused by 2019‐nCoV journal February 2020
The first two cases of 2019‐nCoV in Italy: Where they come from? journal February 2020
Genetic variants and source of introduction of SARS‐CoV‐2 in South America journal July 2020
Surveillance and Control of Zoonotic Agents Prior to Disease Detection in Humans: SURVEILLANCE AND CONTROL OF ZOONOTIC AGENTS
  • Childs, James E.; Gordon, Elizabeth R.
  • Mount Sinai Journal of Medicine: A Journal of Translational and Personalized Medicine, Vol. 76, Issue 5 https://doi.org/10.1002/msj.20133
journal September 2009
Insights from 20 years of bacterial genome sequencing journal February 2015
Enabling trade across borders and food security in Africa journal August 2020
Ecology of zoonoses: natural and unnatural histories journal December 2012
Tracking Changes in SARS-CoV-2 Spike: Evidence that D614G Increases Infectivity of the COVID-19 Virus journal August 2020
The economic impact of SARS: How does the reality match the predictions? journal October 2008
Global trends in emerging infectious diseases journal February 2008
SARS and MERS: recent insights into emerging coronaviruses journal June 2016
Functional assessment of cell entry and receptor usage for SARS-CoV-2 and other lineage B betacoronaviruses journal February 2020
A pneumonia outbreak associated with a new coronavirus of probable bat origin journal February 2020
Genomic recombination events may reveal the evolution of coronavirus and the origin of SARS-CoV-2 journal December 2020
A Novel Coronavirus from Patients with Pneumonia in China, 2019 journal February 2020
Biodiversity and Global Health: Intersection of Health, Security, and the Environment journal April 2021
A public website for the automated assessment and validation of SARS-CoV-2 diagnostic PCR assays journal August 2020
Nextstrain: real-time tracking of pathogen evolution journal May 2018
Enabling the democratization of the genomics revolution with a fully integrated web-based bioinformatics platform journal November 2016
Evolution in action: climate change, biodiversity dynamics and emerging infectious disease journal April 2015
Emerging Infectious Diseases of Wildlife-- Threats to Biodiversity and Human Health journal January 2000
Ecology and economics for pandemic prevention journal July 2020
Emerging Tick-Borne Diseases journal January 2020
Receptor Recognition by the Novel Coronavirus from Wuhan: an Analysis Based on Decade-Long Structural Studies of SARS Coronavirus journal January 2020
Public health surveillance and data collection: general principles and impact on hemophilia care journal April 2012
Next-Generation Sequencing for Biodefense: Biothreat Detection, Forensics, and the Clinic journal March 2019
An Up-to-Date Overview of Therapeutic Agents for the Treatment of COVID-19 Disease journal January 2020
GISAID: Global initiative on sharing all influenza data – from vision to reality journal March 2017
International Rickettsia Disease Surveillance: An Example of Cooperative Research to Increase Laboratory Capability and Capacity for Risk Assessment of Rickettsial Outbreaks Worldwide journal March 2021
Implementation of the International Health Regulations (2005) Through Cooperative Bioengagement journal October 2015
Applying Science: Opportunities to Inform Disease Management Policy with Cooperative Research within a One Health Framework journal January 2016
Editorial: Biological Engagement Programs: Reducing Threats and Strengthening Global Health Security Through Scientific Collaboration journal July 2017