Polyelectrolyte Surface Diffusion in a Nanoslit Geometry

Morrin, Gregory T.; Kienle, Daniel F.; Weltz, James S.; Traeger, Jeremiah C.; Schwartz, Daniel K.

doi:10.1021/acs.macromol.9b02365

Polyelectrolyte Surface Diffusion in a Nanoslit Geometry

Journal Article · Wed May 13 00:00:00 EDT 2020 · Macromolecules

DOI:https://doi.org/10.1021/acs.macromol.9b02365· OSTI ID:1773872

^[1]; ^[2]; Weltz, James S. ^[2]; ^[2]; Schwartz, Daniel K. ^[2]

Univ. of Colorado, Boulder, CO (United States); University of Colorado Boulder
Univ. of Colorado, Boulder, CO (United States)

The surface diffusion of poly-l-lysine (PLL) in a planar nanoslit was studied using convex lens-induced confinement (CLiC) single-molecule tracking microscopy. Here, three surface chemistries were employed to understand the interplay of electrostatic and short-range interactions: an amine-functionalized silica surface, an oligo(ethylene oxide) (OEG)-modified surface, and a 1:1 mixture of the two ligands. Effective surface diffusion coefficients increased rapidly with slit height until saturating for slit heights <30 nm. While diffusion at a semi-infinite interface was significantly faster for OEG surfaces, the diffusion coefficient increased most rapidly with slit height for amine-functionalized surfaces, resulting in surface diffusion within very thin slits being nearly independent of surface chemistry. Intermittent random walks were simulated within a planar slit geometry, using experimentally measured parameters obtained from diffusion at a single interface to account for the characteristic short-range interactions between PLL and each surface chemistry, and were in good agreement with experimental measurements.

View Accepted Manuscript (DOE)

Research Organization:: Univ. of Colorado, Boulder, CO (United States)

Sponsoring Organization:: Defense Threat Reduction Agency (DTRA); National Institute of Standards and Technology (NIST); National Institutes of Health (NIH); National Science Foundation (NSF); USDOE Office of Science (SC), Basic Energy Sciences (BES)

Grant/Contract Number:: SC0001854

OSTI ID:: 1773872

Journal Information:: Macromolecules, Journal Name: Macromolecules Journal Issue: 10 Vol. 53; ISSN 0024-9297

Publisher:: American Chemical SocietyCopyright Statement

Country of Publication:: United States

Language:: English

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