Eighteen new oleaginous yeast species

Garay, Luis A.; Sitepu, Irnayuli R.; Cajka, Tomas; Chandra, Idelia; Shi, Sandy; Lin, Ting; German, J. Bruce; Fiehn, Oliver; Boundy-Mills, Kyria L.

doi:10.1007/s10295-016-1765-3

Eighteen new oleaginous yeast species

Journal Article · Fri Jul 01 00:00:00 EDT 2016 · Journal of Industrial Microbiology and Biotechnology

DOI:https://doi.org/10.1007/s10295-016-1765-3· OSTI ID:1773528

Garay, Luis A. ^[1]; Sitepu, Irnayuli R. ^[2]; Cajka, Tomas ^[3]; Chandra, Idelia ^[1]; Shi, Sandy ^[1]; Lin, Ting ^[1]; German, J. Bruce ^[4]; Fiehn, Oliver ^[5]; Boundy-Mills, Kyria L. ^[1]

grid.27860.3b 0000000419369684 Phaff Yeast Culture Collection, Department of Food Science and Technology University of California One Shields Ave 95616-8598 Davis CA USA
grid.27860.3b 0000000419369684 Phaff Yeast Culture Collection, Department of Food Science and Technology University of California One Shields Ave 95616-8598 Davis CA USA, grid.504251.7 Bioentrepreneurship Department Indonesia International Institute for Life Sciences Jalan Pulo Mas Barat Kav. 88 13210 East Jakarta DKI Jakarta Indonesia
grid.27860.3b 0000000419369684 Metabolomics, UC Davis Genome Center University of California Davis 451 Health Sciences Drive 95616 Davis CA USA
grid.27860.3b 0000000419369684 Department of Food Science and Technology University of California One Shields Ave 95616 Davis CA USA
grid.27860.3b 0000000419369684 Metabolomics, UC Davis Genome Center University of California Davis 451 Health Sciences Drive 95616 Davis CA USA, grid.412125.1 0000000106191117 Biochemistry Department, Faculty of Science King Abdulaziz University PO Box 80203 21589 Jeddah Saudi Arabia

Abstract

Of 1600 known species of yeasts, about 70 are known to be oleaginous, defined as being able to accumulate over 20 % intracellular lipids. These yeasts have value for fundamental and applied research. A survey of yeasts from the Phaff Yeast Culture Collection, University of California Davis was performed to identify additional oleaginous species within the Basidiomycota phylum. Fifty-nine strains belonging to 34 species were grown in lipid inducing media, and total cell mass, lipid yield and triacylglycerol profiles were determined. Thirty-two species accumulated at least 20 % lipid and 25 species accumulated over 40 % lipid by dry weight. Eighteen of these species were not previously reported to be oleaginous. Triacylglycerol profiles were suitable for biodiesel production. These results greatly expand the number of known oleaginous yeast species, and reveal the wealth of natural diversity of triacylglycerol profiles within wild-type oleaginous Basidiomycetes.

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Sponsoring Organization:: USDOE

OSTI ID:: 1773528

Journal Information:: Journal of Industrial Microbiology and Biotechnology, Journal Name: Journal of Industrial Microbiology and Biotechnology Journal Issue: 7 Vol. 43; ISSN 1367-5435

Publisher:: Oxford University PressCopyright Statement

Country of Publication:: Germany

Language:: English

References (60)

Medium optimization for lipid production through co-fermentation of glucose and xylose by the oleaginous yeastLipomyces starkeyi Zhao, Xin; Kong, Xiangli; Hua, Yanyan European Journal of Lipid Science and Technology, Vol. 110, Issue 5 https://doi.org/10.1002/ejlt.200700224	journal	May 2008
Lipids of oleaginous yeasts. Part II: Technology and potential applications Papanikolaou, Seraphim; Aggelis, George European Journal of Lipid Science and Technology, Vol. 113, Issue 8 https://doi.org/10.1002/ejlt.201100015	journal	June 2011
Fat Synthesis by Micro-Organisms and its Possible Applications in Industry Lundin, H. Journal of the Institute of Brewing, Vol. 56, Issue 1 https://doi.org/10.1002/j.2050-0416.1950.tb01516.x	journal	January 1950
Novel mutant strains of Rhodosporidium toruloides by plasma mutagenesis approach and their tolerance for inhibitors in lignocellulosic hydrolyzate: Novel mutant R. toruloides strains and their tolerance for hydrolyzate Qi, Feng; Kitahara, Yuki; Wang, Zitian Journal of Chemical Technology & Biotechnology, Vol. 89, Issue 5 https://doi.org/10.1002/jctb.4180	journal	August 2013
Comparative proteomic analysis of Rhodosporidium toruloides during lipid accumulation Liu, Hongwei; Zhao, Xin; Wang, Fangjun Yeast, Vol. 26, Issue 10 https://doi.org/10.1002/yea.1706	journal	October 2009
4 Genome Data Drives Change at Culture Collections McCluskey, Kevin; Wiest, Aric; Boundy-Mills, Kyria Fungal Genomics https://doi.org/10.1007/978-3-642-45218-5_4	book	January 2014
Lipid biotechnology: A wonderland for the microbial physiologist Ratledge, Colin Journal of the American Oil Chemists' Society, Vol. 64, Issue 12 https://doi.org/10.1007/BF02542498	journal	December 1987
Temperature shifts in regulation of lipids accumulated byLipomyces starkeyi Suutari, M.; Priha, P.; Laakso, S. Journal of the American Oil Chemists’ Society, Vol. 70, Issue 9 https://doi.org/10.1007/BF02545349	journal	September 1993
Consequences ofSporidiobolus pararoseus killer toxin action on sensitive cells Janderová, B.; Gášková, D.; Bendová, O. Folia Microbiologica, Vol. 40, Issue 2 https://doi.org/10.1007/BF02815416	journal	April 1995
Biotechnological production and applications of coenzyme Q10 Choi, Jin-Ho; Ryu, Yeon-Woo; Seo, Jin-Ho Applied Microbiology and Biotechnology, Vol. 68, Issue 1 https://doi.org/10.1007/s00253-005-1946-x	journal	March 2005
Biofuels from microbes Antoni, Dominik; Zverlov, Vladimir V.; Schwarz, Wolfgang H. Applied Microbiology and Biotechnology, Vol. 77, Issue 1 https://doi.org/10.1007/s00253-007-1163-x	journal	September 2007
Multi-copy expression and fed-batch production of Rhodotorula araucariae epoxide hydrolase in Yarrowia lipolytica Maharajh, Dheepak; Roth, Robyn; Lalloo, Rajesh Applied Microbiology and Biotechnology, Vol. 79, Issue 2 https://doi.org/10.1007/s00253-008-1420-7	journal	May 2008
Oily yeasts as oleaginous cell factories Ageitos, Jose Manuel; Vallejo, Juan Andres; Veiga-Crespo, Patricia Applied Microbiology and Biotechnology, Vol. 90, Issue 4 https://doi.org/10.1007/s00253-011-3200-z	journal	April 2011
Characterization of glyceraldehyde-3-phosphate dehydrogenase gene RtGPD1 and development of genetic transformation method by dominant selection in oleaginous yeast Rhodosporidium toruloides Liu, Yanbin; Koh, Chong Mei John; Sun, Longhua Applied Microbiology and Biotechnology, Vol. 97, Issue 2, p. 719-729 https://doi.org/10.1007/s00253-012-4223-9	journal	June 2012
Identification of oleaginous yeast strains able to accumulate high intracellular lipids when cultivated in alkaline pretreated corn stover Sitepu, Irnayuli R.; Jin, Mingjie; Fernandez, J. Enrique Applied Microbiology and Biotechnology, Vol. 98, Issue 17 https://doi.org/10.1007/s00253-014-5944-8	journal	July 2014
Carbon source utilization and inhibitor tolerance of 45 oleaginous yeast species Sitepu, Irnayuli; Selby, Tylan; Lin, Ting Journal of Industrial Microbiology & Biotechnology, Vol. 41, Issue 7 https://doi.org/10.1007/s10295-014-1447-y	journal	May 2014
Single cell oils — have they a biotechnological future? Ratledge, Colin Trends in Biotechnology, Vol. 11, Issue 7 https://doi.org/10.1016/0167-7799(93)90015-2	journal	July 1993
Biosynthesis of lipids by Rhodosporidium toruloides ATCC 10788 Turcotte, G.; Kosaric, N. Journal of Biotechnology, Vol. 8, Issue 3 https://doi.org/10.1016/0168-1656(88)90004-1	journal	July 1988
Yeast Lipid Biotechnology Jacob, Z. Advances in Applied Microbiology https://doi.org/10.1016/S0065-2164(08)70596-3	book	January 1993
Novel microbial lipases: catalytic activity in reactions in organic media Cardenas, F.; de Castro, M. S.; Sanchez-Montero, J. M. Enzyme and Microbial Technology, Vol. 28, Issue 2-3 https://doi.org/10.1016/S0141-0229(00)00278-7	journal	February 2001
Taxonomic Distribution of Alkali-tolerant Yeasts Aono, Rikizo Systematic and Applied Microbiology, Vol. 13, Issue 4 https://doi.org/10.1016/S0723-2020(11)80239-0	journal	October 1990
PAT proteins, an ancient family of lipid droplet proteins that regulate cellular lipid stores Bickel, Perry E.; Tansey, John T.; Welte, Michael A. Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, Vol. 1791, Issue 6 https://doi.org/10.1016/j.bbalip.2009.04.002	journal	June 2009
Carotenoids production from a newly isolated Sporidiobolus pararoseus strain using agroindustrial substrates Valduga, Eunice; Rausch Ribeiro, Arthur Henrique; Cence, Karine Biocatalysis and Agricultural Biotechnology, Vol. 3, Issue 2 https://doi.org/10.1016/j.bcab.2013.10.001	journal	April 2014
Evaluation of Sporidiobolus pararoseus strain YCXT3 as biocontrol agent of Botrytis cinerea on post-harvest strawberry fruits Huang, R.; Che, H. J.; Zhang, J. Biological Control, Vol. 62, Issue 1 https://doi.org/10.1016/j.biocontrol.2012.02.010	journal	July 2012
Manipulation of culture conditions alters lipid content and fatty acid profiles of a wide variety of known and new oleaginous yeast species Sitepu, Irnayuli R.; Sestric, Ryan; Ignatia, Laura Bioresource Technology, Vol. 144 https://doi.org/10.1016/j.biortech.2013.06.047	journal	September 2013
Boosting accumulation of neutral lipids in Rhodosporidium kratochvilovae HIMPA1 grown on hemp (Cannabis sativa Linn) seed aqueous extract as feedstock for biodiesel production Patel, Alok; Pravez, Mohammad; Deeba, Farha Bioresource Technology, Vol. 165 https://doi.org/10.1016/j.biortech.2014.03.142	journal	August 2014
Oleaginous yeasts for biodiesel: Current and future trends in biology and production Sitepu, Irnayuli R.; Garay, Luis A.; Sestric, Ryan Biotechnology Advances, Vol. 32, Issue 7 https://doi.org/10.1016/j.biotechadv.2014.08.003	journal	November 2014
Frontiers of yeast metabolic engineering: diversifying beyond ethanol and Saccharomyces Liu, Leqian; Redden, Heidi; Alper, Hal S. Current Opinion in Biotechnology, Vol. 24, Issue 6 https://doi.org/10.1016/j.copbio.2013.03.005	journal	December 2013
Effects of pectinolytic yeast on the microbial composition and spoilage of olive fermentations Golomb, Benjamin L.; Morales, Vanessa; Jung, Alesia Food Microbiology, Vol. 33, Issue 1 https://doi.org/10.1016/j.fm.2012.09.004	journal	February 2013
Dependence of biodiesel fuel properties on the structure of fatty acid alkyl esters Knothe, Gerhard Fuel Processing Technology, Vol. 86, Issue 10 https://doi.org/10.1016/j.fuproc.2004.11.002	journal	June 2005
An improved high-throughput Nile red fluorescence assay for estimating intracellular lipids in a variety of yeast species Sitepu, I. R.; Ignatia, L.; Franz, A. K. Journal of Microbiological Methods, Vol. 91, Issue 2 https://doi.org/10.1016/j.mimet.2012.09.001	journal	November 2012
Biofuels from microalgae—A review of technologies for production, processing, and extractions of biofuels and co-products Brennan, Liam; Owende, Philip Renewable and Sustainable Energy Reviews, Vol. 14, Issue 2, p. 557-577 https://doi.org/10.1016/j.rser.2009.10.009	journal	February 2010
Lipids from heterotrophic microbes: advances in metabolism research Kosa, Matyas; Ragauskas, Arthur J. Trends in Biotechnology, Vol. 29, Issue 2 https://doi.org/10.1016/j.tibtech.2010.11.002	journal	February 2011
Establishing a platform cell factory through engineering of yeast acetyl-CoA metabolism Chen, Yun; Daviet, Laurent; Schalk, Michel Metabolic Engineering, Vol. 15 https://doi.org/10.1016/j.ymben.2012.11.002	journal	January 2013
“Designer” Biodiesel: Optimizing Fatty Ester Composition to Improve Fuel Properties ^† Knothe, Gerhard Energy & Fuels, Vol. 22, Issue 2 https://doi.org/10.1021/ef700639e	journal	March 2008
Accumulation of High-Value Lipids in Single-Cell Microorganisms: A Mechanistic Approach and Future Perspectives Garay, Luis A.; Boundy-Mills, Kyria L.; German, J. Bruce Journal of Agricultural and Food Chemistry, Vol. 62, Issue 13 https://doi.org/10.1021/jf4042134	journal	March 2014
Enhancement of single cell oil production by Yarrowia lipolytica growing in the presence of Teucrium polium L. aqueous extract Aggelis, George; Komaitis, Michael Biotechnology Letters, Vol. 21, Issue 9, p. 747-749 https://doi.org/10.1023/A:1005591127592	journal	January 1999
Microbial production of fatty-acid-derived fuels and chemicals from plant biomass Steen, Eric J.; Kang, Yisheng; Bokinsky, Gregory Nature, Vol. 463, Issue 7280, p. 559-562 https://doi.org/10.1038/nature08721	journal	January 2010
A multi-omic map of the lipid-producing yeast Rhodosporidium toruloides Zhu, Zhiwei; Zhang, Sufang; Liu, Hongwei Nature Communications, Vol. 3, Issue 1 https://doi.org/10.1038/ncomms2112	journal	January 2012
LipidBlast in silico tandem mass spectrometry database for lipid identification Kind, Tobias; Liu, Kwang-Hyeon; Lee, Do Yup Nature Methods, Vol. 10, Issue 8 https://doi.org/10.1038/nmeth.2551	journal	June 2013
Engineering for biofuels: exploiting innate microbial capacity or importing biosynthetic potential? Alper, Hal; Stephanopoulos, Gregory Nature Reviews Microbiology, Vol. 7, Issue 10 https://doi.org/10.1038/nrmicro2186	journal	October 2009
Semi-synthetic artemisinin: a model for the use of synthetic biology in pharmaceutical development Paddon, Chris J.; Keasling, Jay D. Nature Reviews Microbiology, Vol. 12, Issue 5 https://doi.org/10.1038/nrmicro3240	journal	April 2014
Yeasts for lipid production Ratledge, Colin Biochemical Society Transactions, Vol. 16, Issue 6 https://doi.org/10.1042/bst0161088	journal	December 1988
Regulation of lipid accumulation in oleaginous micro-organisms Ratledge, C. Biochemical Society Transactions, Vol. 30, Issue 6, p. 1047-1050 https://doi.org/10.1042/bst0301047	journal	November 2002
The Metarhizium anisopliae Perilipin Homolog MPL1 Regulates Lipid Metabolism, Appressorial Turgor Pressure, and Virulence Wang, Chengshu; St. Leger, Raymond J. Journal of Biological Chemistry, Vol. 282, Issue 29 https://doi.org/10.1074/jbc.M609592200	journal	July 2007
Yeast tolerance to the ionic liquid 1-ethyl-3-methylimidazolium acetate Sitepu, Irnayuli R.; Shi, Shuang; Simmons, Blake A. FEMS Yeast Research, Vol. 14, Issue 8 https://doi.org/10.1111/1567-1364.12224	journal	November 2014
The proteome analysis of oleaginous yeast Lipomyces starkeyi: Comparative proteomic analysis of Lipomyces starkeyi Liu, Hongwei; Zhao, Xin; Wang, Fangjun FEMS Yeast Research, Vol. 11, Issue 1 https://doi.org/10.1111/j.1567-1364.2010.00687.x	journal	October 2010
A Novel β-Glucosidase from Sporidiobolus pararoseus: Characterization and Application in Winemaking Baffi, Milla A.; Tobal, Thaise; Henrique, João Journal of Food Science, Vol. 76, Issue 7 https://doi.org/10.1111/j.1750-3841.2011.02293.x	journal	August 2011
Caracterización e identificación de aislados de levaduras carotenogénicas de varias zonas naturales del Ecuador Guamán-Burneo, Cristina; Carvajal-Barriga, Javier Universitas Scientiarum, Vol. 14, Issue 2-3 https://doi.org/10.11144/javeriana.SC14-2-3.ceid	journal	June 2009
Associations of Yeasts with Spotted-Wing Drosophila (Drosophila suzukii; Diptera: Drosophilidae) in Cherries and Raspberries Hamby, Kelly A.; Hernández, Alejandro; Boundy-Mills, Kyria Applied and Environmental Microbiology, Vol. 78, Issue 14 https://doi.org/10.1128/AEM.00841-12	journal	May 2012
Control of Lipid Accumulation in the Yeast Yarrowia lipolytica Beopoulos, A.; Mrozova, Z.; Thevenieau, F. Applied and Environmental Microbiology, Vol. 74, Issue 24, p. 7779-7789 https://doi.org/10.1128/AEM.01412-08	journal	October 2008
Lipids of yeasts. Rattray, J. B.; Schibeci, A.; Kidby, D. K. Bacteriological Reviews, Vol. 39, Issue 3 https://doi.org/10.1128/BR.39.3.197-231.1975	journal	January 1975
Genome Sequence of the Oleaginous Red Yeast Rhodosporidium toruloides MTCC 457 Kumar, Shailesh; Kushwaha, Hariom; Bachhawat, Anand Kumar Eukaryotic Cell, Vol. 11, Issue 8 https://doi.org/10.1128/EC.00156-12	journal	August 2012
Oleaginous Yeasts form Uruguay and Antarctica as Renewable Raw Material for Biodiesel Production Pereyra, Virginia American Journal of BioScience, Vol. 2, Issue 6 https://doi.org/10.11648/j.ajbio.20140206.20	journal	January 2014
Meeting report: 2nd workshop of the United States culture collection network (May 19–21, 2014, State College, PA, USA) McCluskey, Kevin; Bates, Scott; Boundy-Mills, Kyria Standards in Genomic Sciences, Vol. 9, Issue 1 https://doi.org/10.1186/1944-3277-9-27	journal	December 2014
Evaluation of single cell oil (SCO) from a tropical marine yeast Yarrowia lipolytica NCIM 3589 as a potential feedstock for biodiesel Katre, Gouri; Joshi, Chirantan; Khot, Mahesh AMB Express, Vol. 2, Issue 1 https://doi.org/10.1186/2191-0855-2-36	journal	January 2012
Characterization of newly isolated oleaginous yeasts - Cryptococcus podzolicus, Trichosporon porosum and Pichia segobiensis Schulze, Ines; Hansen, Silla; Großhans, Steffen AMB Express, Vol. 4, Issue 1 https://doi.org/10.1186/s13568-014-0024-0	journal	March 2014
Cellular carbohydrate composition, DNA base composition, ubiquinone systems, and Diazonium Blue B color test in the genera Rhodosporidium, Leucosporidium, Rhodotorula and related basidiomycetous yeasts. Sugiyama, Junta; Fukagawa, Masao; Chiu, Siu-Wai The Journal of General and Applied Microbiology, Vol. 31, Issue 6 https://doi.org/10.2323/jgam.31.519	journal	January 1985
Isolation of Sporidiobolus ruineniae CO-3 and Characterization of Its Extracellular Protease Kim, Ji Yeon Journal of the Korean Society for Applied Biological Chemistry, Vol. 52, Issue 1 https://doi.org/10.3839/jksabc.2009.001	journal	February 2009
Single Cell Oils Cohen, Zvi; Ratledge, Colin Taylor francis.com https://doi.org/10.4324/9781003040101	reference-book	April 2005

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